A5100382168- Bone health and osteoporosis research
- Bone health and treatments
- Bone Metabolism and Diseases
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Growth Hormone and Insulin-like Growth Factors
- Pituitary Gland Disorders and Treatments
- Bone and Joint Diseases
- Advanced Glycation End Products research
- Genetic Syndromes and Imprinting
- Genomics, phytochemicals, and oxidative stress
- Peripheral Artery Disease Management
- Diabetes Treatment and Management
- Acute Ischemic Stroke Management
- Diabetes Management and Research
- Antiplatelet Therapy and Cardiovascular Diseases
- Ophthalmology and Eye Disorders
- Pharmacological Effects of Natural Compounds
- Curcumin's Biomedical Applications
- Lipoproteins and Cardiovascular Health
- Toxic Organic Pollutants Impact
- Computational Physics and Python Applications
- Metabolism, Diabetes, and Cancer
- Hip and Femur Fractures
- Medical and Biological Sciences
- Adrenal and Paraganglionic Tumors
Kyung Hee University
2016-2025
Korea University
2024
National Institute of Biological Resources
2024
Kyung Hee University Dental Hospital
2019-2023
Bridge University
2021
Yonsei University
2021
University Research Co (United States)
2021
Kyung Hee University Medical Center
2020
Cheil General Hospital and Women's Healthcare Center
2009-2016
Dankook University
2016
The socioeconomic burdens of osteoporosis and related fractures have increased in parallel with population aging. Korea Society Bone Mineral Research published fact sheets on these topics 2017, 2018, 2019. This study provides complied epidemiological data based for understanding current status Korea.
We developed for the first time a smartphone application designed diabetes self-management in Korea and registered patent relevant algorithm. also investigated user satisfaction with change related self-care activities after using application.We conducted questionnaire survey on volunteers who were application. Ninety subjects responded to between June 2012 March 2013. A modified version of Summary Diabetes Self-Care Activities (SDSCA) was used this study.The results exhibited mean subject...
Prolactin is a hormone secreted from lactotroph cells in the anterior pituitary gland to induce lactation after birth. Hyperprolactinemia unrelated common cause of amenorrhea women childbearing age, and consequent decrease gonadotropin-releasing (GnRH) by high prolactin level can result decreased bone mineral density. Osteoporosis skeletal disorder characterized density (BMD) quality, which results strength. In patients with hyperprolactinemia, changes BMD be induced indirectly inhibition...
There is little knowledge of the effect inflammatory markers on prognoses hematoma expansion (HE) in patients with intracranial hemorrhage (ICH). We evaluated impact neutrophil-lymphocyte ratio (NLR) and platelet-lymphocyte (PLR) HE worse outcomes after acute ICH. This study included 520 consecutive ICH from registry database enrolled over 80 months. Patients' whole blood samples were collected upon arrival emergency department. Brain computed tomography scans performed during...
Risk of fragility fractures increases in patients with diabetes mellitus, independent bone mineral density. In the present study, effects advanced glycation end products (AGEs) on differentiation and function osteoblasts osteoclasts were investigated.AGEs 25 mM glucose administered to marrow-derived macrophages MCT3T3-E1 cells. The AGEs osteoclast was investigated using tartrate-resistant acid phosphatase (TRAP) assay. osteoblast alkaline (ALP) activity nodule formation assays. Expression...
Abstract Objective Diagnosing parathyroid carcinoma (PC) is complicated and controversial that early diagnosis intervention are often difficult. Therefore, we aimed to elucidate the protein signatures of PC through quantitative proteomic analyses aid in accurate PC. Design We conducted a retrospective cohort study. Methods performed liquid chromatography with tandem mass spectrometry using formalin-fixed paraffin-embedded samples. For analyses, 23 15 adenoma (PA) tissues were collected from...
Acromegaly is a rare, slowly progressive disease. Its mechanism not fully understood, and epidemiological research on Korean patients with acromegaly scarce. The purpose of this study was to determine the incidence prevalence assess comorbidities survival benefits based treatment options.This nationwide population-based cohort conducted using data Health Insurance Review Assessment claims database evaluate newly diagnosed cases during 2013-2017.During 5-year period, 1,093 were acromegaly....
Carotid artery intima medial thickness (IMT), brachial-ankle pulse wave velocity (baPWV), and ankle-brachial index (ABI) are commonly used surrogate markers of subclinical atherosclerosis in patients with type 2 diabetes mellitus (T2DM). The cardio-ankle vascular (CAVI) is a complement to the baPWV, which affected by blood pressure. However, it unclear marker most sensitive predictor atherosclerotic cardiovascular disease (ASCVD).This was retrospective non-interventional study that enrolled...
The health problem of postmenopausal women is emerging as an important due to the increased aging population. This study investigated association between dietary inflammatory index (DII) and bone markers in women.A cross-sectional was conducted on 132 aged 45-70 years. DII score calculated using 3-day food records divided into tertiles according score. lifestyle factors that could affect mineral density (BMD) were included EuroQol- 5 Dimension (EQ-5D), physical activity, eating habits....
Adequate vitamin D status is essential for bone health. New randomized controlled trials investigating the effect of supplementation on health have recently been published. This position statement updates and expands previous 2015 Korean Society Bone Mineral Research adequate healthy older adults (age ≥ 70 years) those at high risk osteoporosis fracture (adults medications) to maintain serum 25-hydroxy-vitamin (25[OH]D) levels 20 ng/mL but < 50 ng/mL. A 25(OH)D level 30 may be beneficial...
Abstract Context Low-density lipoprotein cholesterol (LDL-C)-lowering therapy is considerably important in preventing cardiovascular disease (CVD) among patients with diabetes. Studies comparing CVD, stroke, and mortality outcomes of low- or moderate-intensity statins ezetimibe combination high-intensity statin monotherapy diabetes remain lacking. Objective This study compared the primary prevention effect myocardial infarction (MI), all-cause death between using Korean National Health...
Abstract The screening rate of diabetic retinopathy (DR) is low despite the importance early diagnosis. We investigated predictive value dietary glutamic acid and aspartic for diagnosis DR using Korea National Diabetes Program cohort study. 2067 patients with type 2 diabetes without were included. baseline intakes energy, assessed a 3-day food records. risk incidence based on intake was analyzed. group older, had higher HbA1c, longer DM duration, lower education level income than non-DR (all...
Objective To develop guidelines and recommendations to prevent treat glucocorticoid-induced osteoporosis (GIOP) in Korea. Methods The Korean Society for Bone Mineral Research the College of Rheumatology developed this guideline based on Guidance Development Clinical Practice Guidelines version 1.0 established by National Evidence-Based Healthcare Collaborating Agency. This was adapting previously-published guidelines, a systematic review quality assessment were conducted. Results applies...
Background: There have been equivocal results in studies of the effects dipeptidyl peptidase-4 inhibitors (DPP-4i) on fractures.In this study, we analyzed effect DPP-4i bone fracture risk a Korean population.Methods: We extracted subjects (n = 11,164) aged 50 years or older from National Health Insurance Service-National Sample Cohort 2.0 2009 to 2014.Our control group included without diabetes 5,582), and our treatment groups with users 1,410) non-users 4,172).The primary endpoint was...
Classifying patients with osteoporosis according to fracture risk and establishing adequate treatment strategies is crucial effectively treat osteoporosis. The Korean Society for Bone Mineral Research has issued a position statement regarding appropriate postmenopausal According previous fragility history, bone mineral density (BMD) test results, assessment tool, several clinical factors, groups are classified into low, moderate, high, very-high-risk groups. In high-risk groups,...
Abstract 2,3,7,8‐Tetrachlorodibenzo‐p‐dioxin (TCDD) has various toxicological effects in adipose tissue. Evidence is accumulating that glabridin, a flavonoid extracted from licorice, beneficial on the regulation of glucose homeostasis. In this study, we investigated whether glabridin suppresses TCDD‐induced loss adipogenic action using 3T3‐L1 adipocytes as cell culture model wasting syndrome. Glabridin effectively suppressed lipid accumulation model. Pretreating cells with increased gene...
Sarpogrelate, a selective 5-HT2 receptor antagonist, is known to have significant effect on antiplatelet action. This study was double-blinded, randomized, paralleled multicenter trial compare the effects of sarpogrelate and aspirin preventing macrovascular complications in patients with type 2 diabetes. The subjects were randomly assigned either sarpogrelateor group. baseline parameters for complications, such as intima media thickness (IMT), ankle-brachial index (ABI), IL-6, serotonin,...
This study is the first report to characterize