Hyun Chul Lee

ORCID: 0000-0002-8838-4752
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About
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Research Areas
  • Pituitary Gland Disorders and Treatments
  • Catalytic Processes in Materials Science
  • Growth Hormone and Insulin-like Growth Factors
  • Catalysis and Oxidation Reactions
  • Diabetes, Cardiovascular Risks, and Lipoproteins
  • Diabetes Management and Research
  • Diabetes Treatment and Management
  • Metabolism, Diabetes, and Cancer
  • Cardiovascular Disease and Adiposity
  • Catalysts for Methane Reforming
  • Cardiovascular Health and Disease Prevention
  • Zeolite Catalysis and Synthesis
  • Mesoporous Materials and Catalysis
  • Atmospheric chemistry and aerosols
  • Thyroid Disorders and Treatments
  • Adrenal and Paraganglionic Tumors
  • Diet and metabolism studies
  • Liver Disease Diagnosis and Treatment
  • Air Quality and Health Impacts
  • Electrocatalysts for Energy Conversion
  • Atmospheric aerosols and clouds
  • Carbon Dioxide Capture Technologies
  • Pancreatic function and diabetes
  • Cardiovascular Function and Risk Factors
  • Cancer Treatment and Pharmacology

Samsung (South Korea)
2014-2024

Yonsei University
2007-2024

Harvard University Press
2022

Corning (United States)
2022

Severance Hospital
2010-2015

Chonnam National University Hospital
2015

Chonnam National University
2008-2012

Konkuk University Medical Center
2012

Konkuk University
2012

Pohang University of Science and Technology
2000-2007

Surface ozone is a severe air pollution problem in the North China Plain, which home to 300 million people. Ozone concentrations are highest summer, driven by fast photochemical production of hydrogen oxide radicals (HO

10.1073/pnas.2015797118 article EN cc-by-nc-nd Proceedings of the National Academy of Sciences 2021-03-01

Abstract Severe events of wintertime particulate air pollution in Beijing (winter haze) are associated with high relative humidity (RH) and fast production sulfate from the oxidation sulfur dioxide (SO 2 ) emitted by coal combustion. There has been considerable debate regarding mechanism for SO oxidation. Here we show evidence field observations a haze event that rapid nitrogen (NO nitrous acid (HONO) takes place, latter producing oxide (N O). Sulfate shifts to larger particle sizes during...

10.1038/s41467-020-16683-x article EN cc-by Nature Communications 2020-06-05

Conventional studies on photocatalytic oxidation reaction have focused primarily hydroxyl radical (•OH) as a major reactive oxygen species (ROS). This perspective may not be suitable for gaseous HCHO photodegradation due to the short lifetime and diffusion length of •OH. Identification divergent ROS understanding their characteristics gas-phase are further required. Here, we report BiOI/TiO2 p-n junction photocatalyst, which uses mobile singlet (1O2) main photooxidation. The introduction...

10.1016/j.apcatb.2023.122463 article EN cc-by-nc-nd Applied Catalysis B Environment and Energy 2023-02-14

Betatrophin/angiopoietin-like protein 8 (ANGPTL8) is a liver-secreted recently identified as potent stimulator of beta cell proliferation in mice. However, it unclear how betatrophin regulated humans with non-alcoholic fatty liver disease (NAFLD). We investigated the role mice and without NAFLD. Serum levels were examined by ELISA 164 subjects, including 96 patients Levels significantly elevated subjects NAFLD compared controls (1.301 ± 0.617 vs. 0.900 0.574 μg/L, P < 0.001), even after...

10.1038/srep24013 article EN cc-by Scientific Reports 2016-04-05

Bacterial cellulose nanofiber (BCNF) with high thermal stability produced by an ecofriendly process has emerged as a promising solution to realize safe and sustainable materials in the large-scale battery. However, understanding of actual behavior BCNF full-cell battery been lacking, yield is still limited for commercialization. Here, we report entire production manufacture. We systematically constructed strain highest (31.5%) increasing metabolic flux improved safety introducing Lewis base...

10.1073/pnas.1905527116 article EN Proceedings of the National Academy of Sciences 2019-09-09

Particulate matter (PM) and volatile organic compounds (VOCs) are recognised as hazardous air pollutants threatening human health. Disposable filters generally used for purification despite frequent replacement waste generation problems. However, the development of a novel regenerable robust filter long-term use is huge challenge. Here, we report on new class facile water-washing ceramic catalyst (CCFs), developed to simultaneously remove PM (>95%) VOCs (>82%) in single-pass maximized space...

10.1038/s41467-023-36050-w article EN cc-by Nature Communications 2023-02-15

Alumina nanotubes, nanofibers, and nanorods were synthesized through a new method based on surfactant-driven hydrothermal process, but without adding any organic solvent. Our procedure provides single-step, low-temperature route to different alumina nanostructures with thermal stability by varying the nature of surfactants.

10.1021/ja029494l article EN Journal of the American Chemical Society 2003-02-13

Highly active bimetallic catalysts, Pt–Co nanoparticles supported on yttriastabilized zirconia (YSZ; see picture) can be prepared in a single step by co-impregnation. This system shows high catalytic activity for the selective oxidation of CO presence excess hydrogen, especially at temperatures below 423 K. Supporting information this article is available WWW under http://www.wiley-vch.de/contents/jc_2002/2007/z603144_s.pdf or from author. Please note: The publisher not responsible content...

10.1002/anie.200603144 article EN Angewandte Chemie International Edition 2006-12-08

Background: Since cancer cells are normally over-expressed cathepsin B, we synthesized dendrimer-methoxy poly(ethylene glycol) (MPEG)-doxorubicin (DOX) conjugates using a B-cleavable peptide for anticancer drug targeting. Methods: Gly-Phe-Leu-Gly was conjugated with the carboxylic acid end groups of dendrimer, which then MPEG amine and doxorubicin by aid carbodiimide chemistry (abbreviated as DendGDP). Dendrimer-MPEG-DOX without linkage also comparison (DendDP). Nanoparticles were prepared...

10.2147/ijn.s87145 article EN cc-by-nc International Journal of Nanomedicine 2015-08-01

Abstract. Geostationary satellite measurements of aerosol optical depth (AOD) over East Asia from the Ocean Color Imager (GOCI) and Advanced Himawari (AHI) instruments can augment surface monitoring fine particulate matter (PM2.5) air quality, but this requires better understanding AOD–PM2.5 relationship. Here we use GEOS-Chem chemical transport model to analyze critical variables determining relationship by simulation observations satellite, aircraft, ground-based datasets. This includes...

10.5194/acp-21-16775-2021 article EN cc-by Atmospheric chemistry and physics 2021-11-18

Growth hormone (GH) can induce an accelerated lipolysis. Impaired secretion of GH in obesity results the consequent loss lipolytic effect GH. Dietary restriction as a basic treatment for is complicated by poor compliance, protein catabolism, and slow rates or weight loss. has anabolic increasing insulin-like growth factor (IGF)-I. We investigated effects dietary on actions, well changes insulin obesity. 24 obese subjects (22 women 2 men; 22–46 years old) were fed diet 25 kcal/kg ideal body...

10.1159/000023319 article EN Hormone Research in Paediatrics 1999-01-01

The systemic treatment with angiogenesis inhibitor has been shown to result in weight reduction and adipose tissue loss various models of obesity. To verify the mechanism CKD-732 (TNP-470 analog) against obesity, we evaluated CKD-732’s peripheral central anti-obesity effects. was injected subcutaneously (s.c.) for 7 days animal intracerebroventricularly (i.c.v.) arcuate nucleus (ARC) lesion mice, ob / normal littermates. Modulation hypothalamic neuropeptide mRNAs after i.c.v. injection ARC...

10.1677/jme.1.02165 article EN Journal of Molecular Endocrinology 2007-04-01

Background: The aim of the present study was to investigate serum levels endothelial progenitor cells (EPCs) in type 2 diabetic patients without documented ischemic disease and association between EPCs atherosclerotic plaque formation carotid artery. Methods Results: A clinic-based, prospective conducted. total 73 subjects were enrolled this after cardiac magnetic resonance imaging ankle-brachial index measurements exclude with disease. Plaque artery measured on ultrasonography. Circulating...

10.1253/circj.cj-11-1499 article EN Circulation Journal 2012-01-01
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