A5101429392- Veterinary Oncology Research
- Membrane Separation Technologies
- Neural dynamics and brain function
- Low-power high-performance VLSI design
- Orthodontics and Dentofacial Orthopedics
- Gastrointestinal Bleeding Diagnosis and Treatment
- VLSI and FPGA Design Techniques
- Abdominal Surgery and Complications
- Oral and Maxillofacial Pathology
- Membrane-based Ion Separation Techniques
- Neuroscience and Neural Engineering
- Parallel Computing and Optimization Techniques
- Soft tissue tumor case studies
- Extraction and Separation Processes
- Gastrointestinal disorders and treatments
- Facial Rejuvenation and Surgery Techniques
- Facial Nerve Paralysis Treatment and Research
- Electromagnetic Compatibility and Measurements
- Medical Imaging and Pathology Studies
- Trauma Management and Diagnosis
- Hemodynamic Monitoring and Therapy
- Antenna Design and Analysis
- Memory and Neural Mechanisms
- Bone Tumor Diagnosis and Treatments
- Cardiovascular Conditions and Treatments
Genome and Company (South Korea)
2024-2025
Korea Aerospace University
2024
Electronics and Telecommunications Research Institute
2023
Kyung Hee University
2018-2022
Bio-Medical Science (South Korea)
2022
Sungkyunkwan University
2014-2020
Samsung (South Korea)
2019
Office of Infectious Diseases
2018
Korea Institute of Civil Engineering and Building Technology
2017
Samsung Medical Center
2014
Bacterial cellulose nanofiber (BCNF) with high thermal stability produced by an ecofriendly process has emerged as a promising solution to realize safe and sustainable materials in the large-scale battery. However, understanding of actual behavior BCNF full-cell battery been lacking, yield is still limited for commercialization. Here, we report entire production manufacture. We systematically constructed strain highest (31.5%) increasing metabolic flux improved safety introducing Lewis base...
Abstract Immunotherapy has profoundly transformed the treatment of advanced cancers, leading to improved clinical outcomes. Despite these successes, many patients remain unresponsive immune checkpoint inhibitors (ICI). Consequently, there is an urgent need for novel treatments who fail respond ICI or develop resistance. We previously identified amyloid precursor protein (APP), a type I transmembrane present in T cells. APP interacts with contactin 4 (CNTN4), expressed tumor cells, and plays...
Abstract Introduction: Immune checkpoint inhibitors (ICIs) have significantly improved response rates and survival, becoming a cornerstone in the treatments for various cancers. ICIs are effective when their target immune checkpoints, most notably PD-L1, expressed tumor cells, less they not. CNTN4 is novel independently to previous targets of ICIs. GENA-104A16, humanized anti-CNTN4 IgG4 (S228P) antibody, binds on cells blocks its interaction with amyloid precursor protein (APP) T cells. This...
Abstract As a novel immune checkpoint, we previously confirmed that contactin 4 (CNTN4) expressed on tumors negatively regulates T cell activity by binding to amyloid precursor protein (APP) cells. Immunohistochemistry analysis revealed high expression of CNTN4 in various tumors, including gallbladder, pancreatic, gastric, endometrial, hepatic, prostatic, bladder cancers, melanoma, and others, while its remains low normal tissues, Based the tumor-specific profile CNTN4, have developed an...
Autonomous locomotion in gastrointestinal (GI) tracts is achieved with a paddling-based capsule endoscope. For this, miniaturized encoder module was developed utilizing MEMS fabrication technology to monitor the position of paddles. The integrated yielded high resolution 0.0025 mm linear motion In addition, PID control method implemented on DSP stroke paddles accurately. As result, average accuracy and standard deviation were measured be 0.037 0.025 by laser sensor for repetitive...
A 5-month-old female pomeranian dog (weighting 0.95 kg) with history of cyanosis, exercise intolerance and delayed growth was presented to Veterinary Teaching Hospital, Gyeongsang National University. Diagnostic imaging studies revealed a dextropositioned over-riding aorta, pulmonic stenosis, ventricular septal defect, right hypertrophy atrial defect. Based on the diagnostic findings, diagnosed as case tetralogy Fallot defect (pentalogy Fallot).
The miniature piezo motor based microdrive which is applicable to the neural signal recording in mice presented. manipulated by micromotion of mobile coupled generating flexural vibration within range 3.8 mm, with resolution 60nm. Advancement electrodes a mouse brain monitored an integrated MR (Magneto-Resistive) sensor. This has length 6.5mm, width 6.5 height 12 mm and total weight 1.63 g only, including PCB for recording. displacement microelectrode was evaluated verified as applying...
The position based feedback control system is proposed in order to improve the locomotive performance of paddling capsular microrobot moving gastrointestinal (GI) tracts. miniaturized optical encoder designed and fabricated for positional mobile microrobot, which results precise positioning with resolution 0.1 mm. Moreover, stroke optimized increase forwarding velocity microrobot. verified by comparing targeted displacement measured one under various loading conditions. evaluated according...
The detection of small amounts free peritoneal gas in the canine patient can pose a diagnostic dilemma. objective this study was to determine how much could be detected ultrasonographically. Ultrasound examinations were carried out after increments (0.1 ml) air intraperitoneally injected. Via ultrasonography, 0.4 ml reliably detected. authors concluded that ultrasonography is very sensitive modality for (above ml).
Recently, many works have shown that adjustable delay buffer (ADB) whose is dynamically can effectively solve the clock skew variation problem in designs with multiple power modes. However, all previous of ADB allocation inherently entail two critical limitations, which are adjusted delays by always increments and low cost sizing has never been or not primarily taken into account. To demonstrate how much overcoming limitations effective resolving constraint, we characterize types ADBs called...
함치성 낭종은 미맹출치의 치관을 둘러싸는 퇴축법랑상피로부터 기원한다. 대부분의 낭은 적출술 또는 조대술로 치료된다. 조대술을 통해 낭 내부의 압력이 감소하고 골의 재생이 일어나면서 낭벽은 정상적인 점막으로 변하게 된다. 조대술은 적출술에 비해 인접 주요 구조물을 보호할 수 있다는 장점이 있다. 본 증례는 5세와 11세 남아의 상악 정중 과잉치와 치수 치료된 하악 유구치 부위에서 발견된 각각의 낭종을 치료한 증례로 모두 낭의 크기가 2개 이상의 영구치의 변위를 발생시킬 정도로 매우 컸다. 환자의 나이가 어리고 커서 이용하여 치료하였고 그 결과 변위된 맹출 방향이 개선되고 방사선투과상의 점점 감소하는 것으로 관찰되었다. 증례와 같이 큰 경우에서 치료할 경우 위치가 변이된 인접치아를 보존하고 자연 맹출을 유도할 있는 양호한 결과가 예상되기에 보고하는 바이다. Dentigerous cyst is the most common developmental odontogenic of jaw...
Abstract As a novel immune checkpoint, we previously confirmed that contactin 4 (CNTN4) regulates T cell activity negatively by binding to amyloid precursor protein (APP) on cells. CNTN4 is highly expressed in various types of tumors, including gallbladder, pancreas, stomach, endometrium, liver, prostate, bladder cancer, melanoma, and other with positive rates over 70% through immunohistochemistry analysis contrast low-level expression normal tissues. Based the tumor-specific profile CNTN4,...
Recently, many works have shown that adjustable delay buffer (ADB) whose is dynamically can effectively solve the clock skew variation problem in designs with multiple power modes. However, all previous of ADB allocation inherently entail two critical limitations, which are adjusted delays by always increments and low cost sizing has never been or not primarily taken into account. To demonstrate how much overcoming limitations effective resolving constraint, we characterize types ADBs called...
This study was conducted to derive a quality factor for the evaluation of an enclosure with metallic wire mesh. The electrical characteristics metal mesh surface can be determined through equivalent impedance conversion; thus, manufactured after analyzing scattering parameters surface. derived simply by measuring single standard antenna bonded 1-port. To verify effectiveness 1-port time domain derivation method, numerical simulation performed using Finite Integration Technique (FIT)...
A precise and implantable micromanipulator is presented for automatically advancing electrodes during single unit recordings in freely-behaving animals. The modular design enhanced clamping mechanism with simple mechanical components are designed to provide reliable linear motion using a piezo motor stroke of 3 mm. To be specific, closed loop control system, based on the position feedback from magnetoresistive (MR) sensor, was implemented overcome non-linear characteristics locate precisely...
In this paper, we tried to derive the membrane fouling characteristics of Chlorella, green algae, under various operating conditions by using a ceramic membrane.To end, study examined effects on membranes according flux and coagulant Chlorella attached surface due backwash (B/W) in filtering membranes.Therefore, relationship between B/W control analyzing phenomenon through filtration resistance analysis each operation condition.When algal-rich water, selection coagulants is an important...
본 ì°êµ¬ì 목ì ì 3ê¸ ë¶ì êµí© íììì facemask를 ì´ì©í ì ì íì¹ë£ ì, ê³ ìì¼ë¡ ì¬ì©í기 ìí´ ì¥ì°©ëë êµ¬ë´ ì¥ì¹ì ì¢ ë¥ì ë°ë¥¸ í¨ê³¼ë¥¼ ë¹êµíë ê²ì´ë¤. íì 18ëª ì ëìì¼ë¡ íì¹ë£ë¥¼ íê· 12ê°ì ëì ìííìì¼ë©°, ì´ ì¤ 9ëª ì ì¥ì¹ë¡ bonded expander를, Hyrax를 ì¬ì©íìë¤. ì¹ë£ ìì , ê·¸ë¦¬ê³ ì§íì 측면ëë¶ë°©ì¬ì ì¬ì§ì ì´¬ìíì¬ ë¹êµ ë¶ìíìë¤. ëí ì ìì¤...