A5101534581- Blood Pressure and Hypertension Studies
- Cardiovascular Disease and Adiposity
- Diabetes Treatment and Management
- Medication Adherence and Compliance
- Cardiovascular Health and Disease Prevention
- Birth, Development, and Health
- Coronary Interventions and Diagnostics
- Cardiovascular Syncope and Autonomic Disorders
- Hepatitis B Virus Studies
- Peripheral Artery Disease Management
- Diet and metabolism studies
- Health Systems, Economic Evaluations, Quality of Life
- Tryptophan and brain disorders
- Pharmaceutical Economics and Policy
- Cardiac Imaging and Diagnostics
- Liver Disease Diagnosis and Treatment
- Cardiac Arrhythmias and Treatments
- Bone health and osteoporosis research
- Cerebrovascular and Carotid Artery Diseases
- Biomarkers in Disease Mechanisms
- Sodium Intake and Health
- Immunotherapy and Immune Responses
- Cardiovascular Function and Risk Factors
- Microbial Natural Products and Biosynthesis
- RNA Interference and Gene Delivery
Gyeongsang National University
2024
Amway (United States)
2023
Gachon University
2021-2022
Yonsei University
2021
Deleted Institution
2011-2012
Inha University
2006
Accumulating evidence indicates that microbial communities in the human body crucially affect health through production of chemical messengers. However, relationship between microbiota and cancer has been underexplored. As a result biochemical investigation commensal oral microbe, Corynebacterium durum, we identified non-enzymatic transformation tryptamine into an anticancer compound, durumamide A (1). The structure 1 was determined using LC-MS NMR data analysis as bis(indolyl)glyoxylamide,...
Abstract Background In this prospective, multicenter, non-comparative observational study, the effectiveness and safety of triple single-pill combination (SPC) olmesartan/amlodipine/hydrochlorothiazide (OM/AML/HCTZ) were evaluated in a real clinical practice setting Korean patients with essential hypertension. Methods A total 3752 enrolled followed for 12 months after administration OM/AML/HCTZ. Primary endpoint was change from baseline to month 6 mean systolic blood pressure (SBP)....
Height declines with age, and its degree differs among individuals. Despite epidemiologic evidence for the inverse relationship between adult height cardiovascular disease (CVD) incidence, clinical significance of loss in CVD remains to be elucidated. Therefore, this study investigated association incidence.In total, 127,573 Korean participants were enrolled; their heights monitored from 2002 2011. The annual (cm/year) was difference first last measurements within observation period divided...
The relationship of blood pressure (BP) with cardio-renal events and all-cause mortality in type 2 diabetes mellitus (T2DM) is still controversial.To investigate the optimal BP target Korean individuals T2DM.Using National Health Insurance System database, data T2DM who underwent regular health checks from January 1, 2007, to December 31, were extracted (N = 1 800 073). Among them, a total 326 593 included final study. study population was divided into 7 groups according their observed...
This study aimed to investigate the long-term effects of diabetes drug costs on cardiovascular (CV) events and death.This retrospective observational used data from 2009 2018 National Health Insurance in Korea. Among patients with type 2 diabetes, those taking antidiabetic drugs who did not have CV until were included. Patients divided into quartiles (Q1 [lowest]-4 [highest]) according cost. In addition, 10-year incidences (non-fatal myocardial infarction, stroke, hospitalization for heart...
Abstract Background Epidemiologic research has confirmed the inverse relationship between adult height and incidence of cardiovascular disease (CVD). Height declines with age its degree differs from person to person. Aim To investigate association loss CVD incidence. Methods In total, 127 573 ethnically Korean patients were enrolled, their (cm) was monitored 2002 2011. The annual (cm/year) calculated as difference first last measurement within observation period divided by number years....
Abstract Question: What is the association between height loss and cardio-/cerebrovascular disease (CVD) incidence? Method: The data we obtained a sample cohort provided by NHIS from 2002 to 2015. chi-square test Kruskal-Wallis were used see group differences in demographic characteristics. To compute primary secondary outcomes, Cox proportional-hazard model, Kaplan-Meier survival curve, logistic regression. Results: cumulative MACCE incidence rate was 3.6 % for Group 1, 4.5 2, 5.2 3. 3 had...
Abstract Background : We aimed to investigate the long-term effects of diabetes drug costs on cardiovascular (CV) events and death. Methods This retrospective observational study used 2009–2018 National Health Insurance data in Korea. Among patients with type 2 diabetes, those who were taking antidiabetic drugs did not have CV before 2009 included. Data annual cost each collected. The 10-year incidence (cardiac death, non-fatal myocardial infarction, stroke, hospitalization for heart...