A5055836983- Metabolism, Diabetes, and Cancer
- Diabetes Treatment and Management
- Nutrition and Health in Aging
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Diabetes Management and Education
- Diet and metabolism studies
- Liver Disease Diagnosis and Treatment
- Pancreatic function and diabetes
- Cardiovascular Disease and Adiposity
- Adipokines, Inflammation, and Metabolic Diseases
- Nutritional Studies and Diet
- Diabetes Management and Research
- Cardiovascular Health and Disease Prevention
- Diabetes and associated disorders
- Health and Wellbeing Research
- Adipose Tissue and Metabolism
- Nutrition, Health and Food Behavior
- Folate and B Vitamins Research
- Bone health and osteoporosis research
- Bariatric Surgery and Outcomes
- Chronic Disease Management Strategies
- Lipoproteins and Cardiovascular Health
- Health Literacy and Information Accessibility
- Peroxisome Proliferator-Activated Receptors
- Neuroblastoma Research and Treatments
Inha University
2016-2025
Inha University Hospital
2008-2024
Incheon Medical Center
2018-2024
Seoul Medical Center
2023
Yonsei University
2003-2008
Catholic Kwandong University
2005
Seoul National University
2005
Korea Institute of Brain Science
2003
Abstract Objective: The objective of this study was to investigate the association among adiposity, insulin resistance, and inflammatory markers [high‐sensitivity C‐reactive protein (hs‐CRP), interleukin (IL)‐6, tumor necrosis factor (TNF)‐α] adiponectin effects exercise training on obese male Korean adolescents. Research Methods Procedures: Twenty‐six 14 lean age‐matched adolescents were studied. We divided subjects into two groups: group ( N = 14) control 12). underwent 6 weeks jump rope...
Abstract The effect of diabetes distress on glycemic control and its association with complications is still poorly understood. We aimed to study the clinical features patients high distress, focusing changes in risk diabetic complications. From Korean National Diabetes Program data, we investigated 1862 individuals type 2 mellitus (T2DM) who completed complication studies version Problem Areas Survey (PAID-K). A total score PAID-K ≥ 40 was considered indicative distress. Individuals (n =...
Summary Objective Chemerin, a recently identified adipokine, has been linked to adiposity, insulin resistance, metabolic syndrome risk factors and inflammation. Here, we evaluated whether 12‐week lifestyle intervention in overweight obese adults with type 2 diabetes could significantly affect the average blood glucose serum chemerin levels over time. Design Thirty‐five or subjects were randomized receive intensive modification including supervised exercise sessions usual care for 12 weeks....
OBJECTIVE—The aim of this study was to assess the incidence posttransplantation diabetes mellitus (PTDM) in renal allograft recipients and investigate factors contributing onset progression PTDM its underlying pathogenic mechanism(s). RESEARCH DESIGN AND METHODS—A total 77 patients with normal glucose tolerance (NGT) were enrolled study. An oral test performed 1 week before transplantation repeated at 7 years after transplantation. RESULTS—The overall 39% year 35.1% posttransplantation. The...
Abstract Type 2 diabetes mellitus (T2DM) significantly impacts on human health and patient numbers are predicted to rise. Discovering novel drugs targets for treating T2DM is a research priority. In this study, we investigated targeting of the glycolysis enzyme, enolase, using small molecule ENOblock, which binds enolase modulates its non-glycolytic ‘moonlighting’ functions. insulin-responsive cells ENOblock induced nuclear translocation, where enzyme acts as transcriptional repressor....
Nonalcoholic fatty liver disease (NAFLD) is associated with chronic kidney (CKD). However, the causal relationship between NAFLD and CKD uncertain, particularly in patients type 2 diabetes mellitus (T2DM). We aimed to investigate association presence severity of incident T2DM.In this longitudinal cohort study T2DM, 3,188 preserved renal function were followed up for occurrence CKD. was defined as hepatic steatosis on ultrasonography, without any other causes disease. Advanced fibrosis a...
This study evaluated the efficacy and safety of enavogliflozin, a novel sodium-glucose cotransporter 2 inhibitor, versus dapagliflozin in Korean patients with type diabetes mellitus (T2DM) inadequately controlled metformin gemigliptin.In this multicenter, double-blind, randomized study, inadequate response to (≥ 1000 mg/day) plus gemigliptin (50 were receive enavogliflozin 0.3 mg/day (n = 134) or 10 136) addition therapy. The primary endpoint was change HbA1c from baseline week 24.Both...
Many older patients with COVID-19 likely have co-morbid osteoporosis. We investigated the clinical outcomes of This was a retrospective cohort study using national claims data from Korea encoded in common model. Patients aged ≥ 50 years diagnosed infection between January 2020 and April 2022 were included stratified into two groups according to history Clinical analyzed logistic regression analysis after large-scale propensity score stratification. Of 597,011 study, 105,172 had In...
Objective To comprehensively assess the relationship between nerve conduction study (NCS), sympathetic skin response (SSR), and demographic factors in patients with diabetic neuropathy, exploring potential risk mechanisms. Methods A retrospective (N=184) included diagnosed type 2 diabetes mellitus undergoing NCS SSR. Demographic, clinical, laboratory data were analyzed. Patients categorized by peripheral neuropathy (DPN) SSR stages for comparative analysis. Results HbA1c levels correlated...
Summary Objective We examined the individual pharmacological effects of addition rosiglitazone and metformin to glimepiride on inflammatory markers adipokines in patients with type 2 diabetes mellitus. analysed relationships between these variables, measurements insulin sensitivity β‐cell function treated plus glimepiride. Design One hundred twenty (120) mellitus were randomized or for 12 weeks. The plasma concentrations measured at baseline after Measurements Markers determined by...
Background: Metformin is considered the first choice oral treatment for type 2 diabetes patients in absence of contraindications.Rarely, life-threatening complications associated with metformin are seen some underlying diseases.The aim this study was to further investigate clinical profiles and risk factors metformin-associated lactic acidosis (MALA) modalities according survival.Methods: To identify MALA, we performed a retrospective seven diabetic who were taking had been diagnosed at Inha...
This study aimed to investigate the association between low muscle mass or sarcopenic obesity and risk of incident chronic kidney disease (CKD) in patients with type 2 diabetes mellitus (T2DM).A total 3123 T2DM preserved renal function were followed up for CKD. Skeletal was estimated from bioelectrical impedance analysis. CKD defined as glomerular filtration rate < 60 mL/min/1.73 m2 . Sarcopenic coexistence sarcopenia abdominal obesity.During 8.9 years follow-up, 530 (17.0%) developed When...
Background: We aimed to evaluate whether non-alcoholic fatty liver disease (NAFLD) with or without sarcopenia is associated progression of carotid atherosclerosis in patients type 2 diabetes mellitus (T2DM).Methods: investigated 852 T2DM who underwent abdominal ultrasonography, bioelectrical impedance analysis, and artery ultrasonography at baseline repeated after 6 8 years. NAFLD was confirmed by defined as a sex-specific skeletal muscle mass index (SMI) value <2 standard deviations...
Untreated hyperthyroidism and high-dose thyroid hormone are associated with osteoporosis, increased bone mineral density (BMD) has been demonstrated in postmenopausal females hypoparathyroidism.Studies on the effect of suppressive levothyroxine (LT4) therapy BMD metabolism after total thyroidectomy patients differentiated carcinoma have presented conflicting results, few studies relation to status hypoparathyroidism studied.One hundred women 24 premenopausal LT4 suppression were included...
Background The aim of the study was to assess impact socioeconomic status (SES) on health behaviors, metabolic control, and chronic complications in people with type 2 diabetes mellitus (T2DM) from South Korea, a country universal insurance coverage that has experienced rapid economic social transition. Methods A total 3,294 Korean men women T2DM aged 30 65 years, participating National Diabetes Program (KNDP) cohort who reported their SES had baseline clinical evaluation were included...