A5045382716- Diabetes Treatment and Management
- Liver Disease Diagnosis and Treatment
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Metabolism, Diabetes, and Cancer
- Nutrition and Health in Aging
- Lipoproteins and Cardiovascular Health
- Diet, Metabolism, and Disease
- Diabetes Management and Research
- Cardiovascular Disease and Adiposity
- Pancreatitis Pathology and Treatment
- Diabetes Management and Education
- Cancer, Lipids, and Metabolism
- Pancreatic function and diabetes
- Bone health and osteoporosis research
- Diet and metabolism studies
- Hepatitis C virus research
- Thyroid Cancer Diagnosis and Treatment
- Parkinson's Disease Mechanisms and Treatments
- Folate and B Vitamins Research
- Diabetes and associated disorders
- Renal Transplantation Outcomes and Treatments
- Nutritional Studies and Diet
- Liver Diseases and Immunity
- Bariatric Surgery and Outcomes
- Thyroid Disorders and Treatments
Inha University
2018-2025
Yonsei University
2010-2024
Inha University Hospital
2020-2024
University School
2023
Korea University
2023
Ajou University
2023
Incheon Medical Center
2020-2021
Weatherford College
2020
Yong In University
2019
Daegu University
2018
This report presents the recent prevalence and comorbidities related to diabetes in Korea by analyzing nationally representative data.Using data from National Health Nutrition Examination Survey for 2013 2014, percentages total number of subjects over age 30 years with prediabetes were estimated applied Population Census 2014. Diagnosis was based on fasting plasma glucose (≥126 mg/dL), current taking antidiabetic medication, history previous diabetes, or glycosylated hemoglobin (HbA1c)...
Background This study aimed to investigate the recent prevalence, management, and comorbidities of diabetes among Korean adults aged ≥30 years by analyzing nationally representative data. Methods used data from Korea National Health Nutrition Examination Survey 2016 2018, percentage total number people age with impaired fasting glucose (IFG) were estimated. Results In 13.8% had diabetes, ≥65 showed a prevalence rate 28%. The IFG was 26.9% in years. From 35% subjects not aware their...
Abstract Background The effect of ezetimibe, Niemann-Pick C1-like 1 inhibitor, on liver fat is not clearly elucidated. Our primary objective was to evaluate the efficacy ezetimibe plus rosuvastatin versus monotherapy reduce using magnetic resonance imaging-derived proton density fraction (MRI-PDFF) in patients with non-alcoholic fatty disease (NAFLD). Methods A randomized controlled, open-label trial 70 participants NAFLD confirmed by ultrasound who were assigned receive either 10 mg 5 daily...
Abstract The effect of diabetes distress on glycemic control and its association with complications is still poorly understood. We aimed to study the clinical features patients high distress, focusing changes in risk diabetic complications. From Korean National Diabetes Program data, we investigated 1862 individuals type 2 mellitus (T2DM) who completed complication studies version Problem Areas Survey (PAID-K). A total score PAID-K ≥ 40 was considered indicative distress. Individuals (n =...
OBJECTIVE Dipeptidyl peptidase 4 inhibitors (DPP-4i) are useful incretin-based antidiabetes drugs. However, there is a concern that DPP-4i may adversely impact the exocrine pancreas, owing to their pleiotropic effects. In this study, we investigated whether associated with pancreatitis and pancreatic cancer using nationwide population-based cohort study. RESEARCH DESIGN AND METHODS We included patients newly diagnosed type 2 diabetes who were treated drugs (n = 33,208) from 2007 2013. The...
Nonalcoholic fatty liver disease (NAFLD) is associated with chronic kidney (CKD). However, the causal relationship between NAFLD and CKD uncertain, particularly in patients type 2 diabetes mellitus (T2DM). We aimed to investigate association presence severity of incident T2DM.In this longitudinal cohort study T2DM, 3,188 preserved renal function were followed up for occurrence CKD. was defined as hepatic steatosis on ultrasonography, without any other causes disease. Advanced fibrosis a...
Abstract Background There is increasing concern regarding cardiovascular risk in individuals with non-alcoholic fatty liver disease. This study was conducted to evaluate whether hepatic steatosis or without fibrosis associated the progression of carotid atherosclerosis patients type 2 diabetes. Methods From a longitudinal cohort, we enrolled 1120 diabetes who underwent repeated artery ultrasonography every 1–2 years. Ultrasonographic findings at baseline and after 6–8 years were compared....
This study aimed to investigate the association between low muscle mass or sarcopenic obesity and risk of incident chronic kidney disease (CKD) in patients with type 2 diabetes mellitus (T2DM).A total 3123 T2DM preserved renal function were followed up for CKD. Skeletal was estimated from bioelectrical impedance analysis. CKD defined as glomerular filtration rate < 60 mL/min/1.73 m2 . Sarcopenic coexistence sarcopenia abdominal obesity.During 8.9 years follow-up, 530 (17.0%) developed When...
Background: We aimed to evaluate whether non-alcoholic fatty liver disease (NAFLD) with or without sarcopenia is associated progression of carotid atherosclerosis in patients type 2 diabetes mellitus (T2DM).Methods: investigated 852 T2DM who underwent abdominal ultrasonography, bioelectrical impedance analysis, and artery ultrasonography at baseline repeated after 6 8 years. NAFLD was confirmed by defined as a sex-specific skeletal muscle mass index (SMI) value <2 standard deviations...
Many older patients with COVID-19 likely have co-morbid osteoporosis. We investigated the clinical outcomes of This was a retrospective cohort study using national claims data from Korea encoded in common model. Patients aged ≥ 50 years diagnosed infection between January 2020 and April 2022 were included stratified into two groups according to history Clinical analyzed logistic regression analysis after large-scale propensity score stratification. Of 597,011 study, 105,172 had In...
Sodium glucose cotransporter 2 (SGLT2) inhibitors improve clinical outcomes in several populations including type diabetes (T2D), chronic renal insufficiency, and heart failure (HF). However, limited data exist on their effects atrial fibrillation (AF). We conducted a retrospective cohort study using the National Health Insurance Service database. A total of 4,771 patients with T2D AF who were newly prescribed SGLT2 or DPP4 selected matched 1:2 ratio by propensity score 37 confounding...
Abstract Statins have been reported to prevent the development of hepatocellular carcinoma (HCC). We examined whether statin therapy is associated with decreased HCC recurrence in patients who underwent liver transplantation for HCC. Three hundred forty-seven ≥ 20 years old from 2006 2016 were enrolled this study. Statin was defined as administration statins more than 30 days after transplantation. One twelve (32.3%) treated over group, and remaining 235 (67.7%) non-statin group. Several...
We evaluated the effects of two dipeptidyl peptidase-4 (DPP-4) inhibitors, sitagliptin and vildagliptin, on metabolic parameters in patients with type 2 diabetes mellitus.A total 170 treated or vildagliptin for more than 24 weeks were selected. The separated into groups, (100 mg once daily, n=93) (50 twice n=77). compared effect each DPP-4 inhibitor parameters, including fasting plasma glucose (FPG), postprandial (PPG), glycated hemoglobin (HbA1c), albumin (GA) levels, lipid at baseline...
: Type 2 diabetes mellitus (T2DM) is a major contributor to cognitive decline and dementia in older adults; however, the role of age onset T2DM younger patients remains uncertain. We explored association between risk its subtypes relation at diagnosis.
New-onset diabetes after transplantation (NODAT) and dyslipidemia are important metabolic complications liver (LT) that can adversely affect both allograft patient survival. Statins used as first-line therapies for because of their effectiveness safety profile. However, it has recently been reported statin therapy is associated with new-onset in the nontransplant population. The aim this study was to investigate association between development NODAT LT recipients. Three hundred sixty-four...
Background: This study compared the glycemic effectiveness of three metformin-based dual therapies according to baseline hemoglobin A1c (HbA1c) evaluate appropriateness guideline enforced by National Health Insurance Corporation Korea for initial medication type 2 diabetes (T2D).Methods: prospective observational was conducted across 24 weeks drug-naïve Korean T2D patients with HbA1c greater than 7.5%.Subjects were first divided into groups based on agent combined metformin (group 1,...
Despite numerous studies, the effects of ezetimibe on glucose metabolism are poorly understood. Here, we aimed to investigate and expression inflammatory markers. Thirteen rats were randomly assigned an (n = 6) or control group 7). The received a high fat diet (HFD; 60 Kcal%), whereas HFD (60 Kcal%) containing 160 mg/kg ezetimibe. After 14 weeks, adipose liver tissues, along with plasma, collected comparatively analyzed. combination therapy statins investigated over 1-year period using data...
Background We investigated the predictive markers for therapeutic efficacy and best combination of sodium-glucose co-transporter 2 (SGLT2) inhibitors (empagliflozin, dapagliflozin, ipragliflozin) therapy in patients with type diabetes mellitus (T2DM). Methods A total 804 T2DM who had taken SGLT2 inhibitor as monotherapy or an add-on were analyzed. Multivariate regression analyses performed to identify predictors response including classes baseline anti-diabetic medications. Results After...