A5072621728- Gout, Hyperuricemia, Uric Acid
- Gastric Cancer Management and Outcomes
- Nutrition and Health in Aging
- Pancreatitis Pathology and Treatment
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Diabetes Treatment and Management
- Pregnancy and preeclampsia studies
- Lung Cancer Treatments and Mutations
- Helicobacter pylori-related gastroenterology studies
- Hemophilia Treatment and Research
- Tuberculosis Research and Epidemiology
- Thyroid and Parathyroid Surgery
- Dementia and Cognitive Impairment Research
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Ectopic Pregnancy Diagnosis and Management
- Music Therapy and Health
- Trauma and Emergency Care Studies
- COVID-19 Clinical Research Studies
- Healthcare and Venom Research
- Gestational Diabetes Research and Management
- Traumatic Brain Injury Research
- Cancer survivorship and care
- Remote Sensing in Agriculture
- Body Composition Measurement Techniques
- Pregnancy and Medication Impact
Boramae Medical Center
2021-2024
Biomedical Research Institute
2024
Seoul Metropolitan Government
2022-2023
Seoul National University
2022-2023
Yonsei University
2016-2023
National Cancer Center
2023
Seoul National University Hospital
2023
Jilin Agricultural University
2023
Jilin University
2023
Sungkyunkwan University
2015-2019
This prospective study sought to investigate serum levels of trace elements (cobalt, copper, zinc, and selenium) assess their effects on pregnancy neonatal outcomes. Serum in 245 Korean pregnant women (median gestational age at delivery was 39 + 4 weeks interquartile range 38 4-40 1 weeks) were compared with those 527 general adults previous studies other ethnic groups. Pregnancy outcomes including diabetes, preeclampsia, birth weight, congenital abnormalities assessed. The median element...
The SARS-CoV-2 variants of concern exhibit distinct features in terms transmissibility and virulence. This study compared the clinical characteristics COVID-19 children during pre-Delta, Delta Omicron waves.Medical records 1163 <19 years age with admitted to a designated hospital Seoul, South Korea, were analyzed. Clinical laboratory findings pre-Delta (March 1, 2020, June 30, 2021; 330 children), (July 2021, December 31, 527 children) (January 2022, May 10, 2022; 306 waves compared.Children...
Purpose We investigated whether thymidylate synthase (TS) expression is a predictive marker for the clinical outcome of pemetrexed/cisplatin in patients with nonsquamous non–small-cell lung cancer. Patients and Methods Eligible were tested TS by immunohistochemistry stratified into either TS-negative or TS-positive group. After stratification, each group randomly assigned (1:1 ratio) to receive gemcitabine/cisplatin maximum six cycles until disease progression. The primary end point was...
recent studies suggest that handgrip strength is linked with cognitive impairment at older ages. However, it remains unclear as to whether muscular influences subsequent performance, or lower levels of function increase the likelihood muscle decline. investigate directional relationship between and using longitudinal data among adults. repeated measures were collected in a sample 5,995 participants Korean Longitudinal Study Aging (KLoSA) over period 8 years. Time-lagged general estimating...
OBJECTIVE Dipeptidyl peptidase 4 inhibitors (DPP-4i) are useful incretin-based antidiabetes drugs. However, there is a concern that DPP-4i may adversely impact the exocrine pancreas, owing to their pleiotropic effects. In this study, we investigated whether associated with pancreatitis and pancreatic cancer using nationwide population-based cohort study. RESEARCH DESIGN AND METHODS We included patients newly diagnosed type 2 diabetes who were treated drugs (n = 33,208) from 2007 2013. The...
Objective To examine whether reduced handgrip strength, as a marker of muscle weakness, is linked with the risk cardiovascular, cancer and all-cause mortality among older adults. Design We used data from 2006 to 2014 Korean longitudinal study ageing study. Estimates strength were collected using handheld dynamometer. Cox proportional hazard models time-varying covariates estimate HRs their 95% CIs for mortality. The cause-specific hazards regression analysis was also model cardiovascular...
Abstract Background The clinical relevance and general applicability of the 8th American Joint Committee on Cancer TNM gastric cancer staging system vs 7th version have not been examined using datasets from both East West. Methods Patients (n = 29 984) treated for adenocarcinoma at two high‐volume centers (Severance Hospital [SH] Gangnam Severance [GSH]) in Korea data Surveillance, Epidemiology, End Results (SEER) database were retrospectively analyzed. Survival curves, performance tumor...
Although improvements in acute care for traumatic brain injury (TBI) have increased the patient survival rate, many survivors often suffer from neuropsychiatric sequelae such as depression. This study investigated influence of TBI on risk depression using South Korean nationwide data. Data were extracted National Health Insurance Service database patients who experienced 2010 to 2017 (n = 1,141,593) and 1:1 matched controls without 1,141,593). Patients under 18 years old or with a history...
Endometriosis is a major cause of infertility, and considering its pathophysiology, it expected to affect pregnancy outcomes as well. This study aimed evaluate whether endometriosis associated with adverse after successful conception. Data from singleton deliveries between January 2014 October 2019 were obtained the Korean Health Insurance Review Assessment Service database. We compared clinical characteristics women without endometriosis. A total 1,251,597 pregnant enrolled; these, 32,951...
Recent studies have shown that gestational diabetes mellitus (GDM) is associated with an increased risk for cardiovascular disease. GDM has also been to be a factor type 2 (T2DM) after pregnancy. However, there limited evidence regarding the role of intercurrent T2DM on relationship between and future CVD. Thus, we investigated risks incident events among women during pregnancy compared without whether CVD dependent development T2DM. We conducted population-based retrospective cohort study...
Spinal sarcopenia is a multifactorial disorder associated with atrophy and fatty changes in paraspinal muscles. Interventional studies for spinal are limited. We aimed to evaluate the effectiveness of combined exercise nutrition intervention treatment sarcopenia.35 community-dwelling older women diagnosed previous cohort study were included. The 12-week consisted back extensor strengthening exercises protein supplementation. following outcomes measured at baseline (week 0), after 12),...
This study examined maternal and pregnancy risk factors for haemolytic nonhaemolytic neonatal jaundice in a large population-based cohort study.We conducted of 1 019 220 singleton live births from the Swedish medical birth register 1987 to 2002, using information on characteristics. Diagnoses gestational hypertensive disorders were obtained by linkage national inpatient register. Multivariate logistic regression analysis provided odds ratios both forms jaundice.A total 6057 (0.6%) affected...
A safe, effective vaccine for breastfeeding infants born to HIV-1-positive mothers could complement antiretroviral therapy (ART) prevention of mother-to-child transmission HIV-1. To date, only a few HIV-1 candidates have been tested in infants. phase I/II randomized controlled trial PedVacc 002 was conducted determine the safety and immunogenicity single, low dose MVA.HIVA delivered intramuscularly healthy 20-week-old Nairobi, Kenya. Pregnant women 2nd/3rd trimester gestation were enrolled,...
ABSTRACT Introduction Reports on patients’ satisfaction and preferred characteristics for treatments would be worthwhile when choosing an optimal treatment reflecting perspectives. Aim To identify the patterns of patients with haemophilia A, or their caregivers, in Korea explore patient preferences treatment. Methods This cross‐sectional, multicentre, observational study was conducted from April 2018 to September 2019 at six nationwide hospitals three Hemophilia Foundation clinics. Patients...
In South Korea, public-private mix (PPM) was launched in 2011. This retrospective cohort study sought to determine the rate of loss follow-up (LTFU) among drug-susceptible tuberculosis (DS-TB) patients all nationwide PPM institutions, and risk factors for LTFU. National notification data DS-TB diagnosed between August 2011 July 2014 institutions were analysed. Determination LTFU included detection instances where transferred out, but when they did not attend at other TB centres following two...
Introduction Low-dose radiation therapy (LDRT) for osteoarthritis (OA) has been performed several decades. However, supporting evidence from randomised studies using modern methodologies is lacking, and a recently published study failed to show the significant benefit of LDRT. The presented trial aims evaluate efficacy safety LDRT patients with knee OA. Methods analysis This prospective, multicentre, will be conducted in Republic Korea. A total 114 participants randomly assigned (1:1:1)...
18 Background: Recently, the 8th AJCC TNM staging system for estimating prognosis patients with gastric cancer was revised new subgroups. There are little number of studies have shown its validation other datasets. We aimed to validate by using various datasets large gastrectomies. Methods: retrospectively reviewed data 17160, 11324 and 1500 treated in Yonsei University Severance Hospital (SH), The Surveillance, Epidemiology, End Results (SEER) Gangnam (GSH), respectively. Survival curves...
Abstract Background As significant advances in the field of treatment for rheumatoid arthritis (RA), there is a great need to identify healthcare outcomes such as satisfaction and health-related quality life (HRQoL) patients with various options. This study aims difference HRQoL RA using different options, by comparing treated tofacitinib adalimumab real-world settings Korea, propensity score methods. Methods In this non-interventional, multicenter, cross-sectional (NCT03703817), total 410...
21 Background: Current TNM staging system for gastric cancer has controversies regarding N classification. We aimed to develop a simple and novel by re-grouping Methods: retrospectively reviewed 14260 patients treated cancer. To combinations of with similar weighted value between T classification, classification was restructured different cutoffs. The optimal cutoffs the number metastatic lymph node which maximize x 2 statistic log-rank test survival differences among were selected....