A5101400281- Ovarian cancer diagnosis and treatment
- Endometriosis Research and Treatment
- Endometrial and Cervical Cancer Treatments
- Cervical Cancer and HPV Research
- Uterine Myomas and Treatments
- Reproductive System and Pregnancy
- Intraperitoneal and Appendiceal Malignancies
- Health and Wellbeing Research
- Pregnancy and preeclampsia studies
- Ectopic Pregnancy Diagnosis and Management
- Mesenchymal stem cell research
- Healthcare Education and Workforce Issues
- Intimate Partner and Family Violence
- Prenatal Screening and Diagnostics
- Maternal and fetal healthcare
- Maternal and Perinatal Health Interventions
- Ovarian function and disorders
- Tissue Engineering and Regenerative Medicine
- Urinary and Genital Oncology Studies
- Healthcare and Venom Research
- Diverse Approaches in Healthcare and Education Studies
- Health Systems, Economic Evaluations, Quality of Life
- Sexual Assault and Victimization Studies
- Pharmaceutical studies and practices
- Organ and Tissue Transplantation Research
Boramae Medical Center
2010-2024
Seoul National University
2013-2024
Seoul Metropolitan Government
2010-2024
Albert Einstein College of Medicine
2021
Korea University Medical Center
2016
Seoul National University Hospital
2009-2010
Hanyang University
2002-2007
Wharton’s jelly is not only one of the most promising tissue sources for mesenchymal stem cells (MSCs) but also a source natural growth factors. To prove that we can get both factors and MSCs from jelly, compared cellular characteristics level basic fibroblast factor (bFGF) samples using explant culture method to those derived traditional enzymatic method. The levels bFGF were<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"...
This study aimed to identify the candidate miRNAs in carcinogenesis of endometrial carcinoma, and explore whether FFPE material would be suitable for miRNA profiling. We identified differences between expression profiles using human microarray endometrioid adenocarcinomas (EECs) normal endometria. Of those tested, miR-200a*, miR-200b*, miR-141, miR-182, miR-205 were greatly enriched. The expressions these five validated quantitative real-time reverse transcription-PCR (qRT-PCR). then...
To determine the success rate of "intended conservative management strategy" ruptured ovarian cysts with hemoperitoneum and risk factors for surgical interventions in healthy women reproductive age.Patients who visited emergency department abdominal pain were diagnosed a cyst between August 2008 June 2013 included this retrospective study. The diagnosis was based on clinical symptoms, physical examination ultrasound CT imaging. intervention determined.A total 78 hemoperitoneum. Most patients...
Endometriosis is a major cause of infertility, and considering its pathophysiology, it expected to affect pregnancy outcomes as well. This study aimed evaluate whether endometriosis associated with adverse after successful conception. Data from singleton deliveries between January 2014 October 2019 were obtained the Korean Health Insurance Review Assessment Service database. We compared clinical characteristics women without endometriosis. A total 1,251,597 pregnant enrolled; these, 32,951...
Objective: To evaluate the determinant pretreatment CT findings that can predict surgical intervention for patients suffering from corpus luteal cyst rupture with hemoperitoneum.Materials and Methods: From January 2009 to December 2014, a total of 106 female (mean age, 26.1 years; range, 17-44 years) who visited emergency room our institute acute abdominal pain were subsequently diagnosed ruptured hemoperitoneum included in retrospective study.The analysis size, shape, sentinel clot sign,...
Vulvar hematomas are uncommon outside of the obstetric population and may be result trauma to perineum. most often present with low abdominal pain urologic neurologic symptoms. The vulva has rich vascularization that is supplied by pudendal artery, a branch anterior division internal iliac artery. We describe rare case 15-cm-sized vulvar hematoma suggested rupture pseudoaneurysm left artery without injury. A 14-year-old girl presented sudden swelling in her labium was successfully treated...
Objective The purpose of our study was to assess computed tomographic (CT) findings adnexal torsion through a matched case-control analysis. Materials and methods This retrospective, single-institution included 43 women with age- ovarian mass-matched control women. CT images were evaluated independently by two readers for the following: prominent peripheral follicles, uterine deviation, thickened pedicles, whirl sign, navel sign. Comparisons performed using Chi square test receiver operating...
The aim of this study was to investigate the effect insulin sensitizing agents on hormonal and metabolic parameters as well menstrual patterns in women with polycystic ovary syndrome (PCOS).One hundred twenty-three patients PCOS were included. Metformin administered at 1,500 mg or 1,700 daily for 3 months. If had no improvement cycle metformin-related adverse effects developed, changed medication a dose either 15 pioglitazone up 45 mg. Then resumption regular recovery ovulation evaluated....
Pregnancy is a major risk factor of thromboembolism, and the patients with preeclampsia (PE) are known to have higher thromboembolic complications than normal pregnant women. D-dimer well-established laboratory marker for screening venous thromboembolism (VTE), but concentrations d-dimer tend increase physiologically in women throughout gestational age. We performed this study evaluate clinical significance hypertensive disorders (GHD) according severity.Retrospective cohort was one...
PURPOSE To determine whether the prognostic impact of lymph node ratio (LNR), defined as between number positive nodes and removed nodes, differs open minimally invasive surgical approaches for radical hysterectomy (RH) in node-positive, early-stage cervical cancer. MATERIALS AND METHODS We retrospectively identified 2009 International Federation Gynecology Obstetrics stage IB1-IIA2 patients who underwent primary type C RH 2010 2018. Among them, only those with pathologically proven...
Gestational Age-specific Cut-off Values Are Needed for Diagnosis of Subclinical Hypothyroidism in Early PregnancyDuring the first trimester pregnancy, thyroid-stimulating hormone (TSH) > 2.5 mIU/L has been suggested as universal criterion subclinical hypothyroidism.However, TSH levels change continuously during even trimester.Therefore use a fixed cut-off value may result different diagnosis rate hypothyroidism according to gestational age.The objective this study was obtain normal reference...
Purpose: The purpose of this study was to try understand the essence experience early turnover new nurse by applying phenomenological method and provide basic data for a community-based management program. Method: Phenomenological approach used identify subjects experience. Subjects were five nurses, with less than one year clinical in practice. This in-depth interview. Results: there 104 meaningful sentences or phrases, 41 generally comprehensive thema. Finally, thema classified into 12...
Objective We evaluated the incidence of newly diagnosed gestational diabetes mellitus (GDM) during 3rd trimester in women with suspected large for age (LGA) fetuses on ultrasound and assessed their perinatal outcomes. Methods A retrospective cohort study was performed. Singleton pregnant LGA whose results GDM screening at midpregnancy had been normal were enrolled. All participants retested 100-g oral glucose tolerance test (OGTT) within 2 days after diagnosis LGA. compared outcomes between...
This study aimed to investigate the impact of adjuvant radiotherapy (RT) on survival outcomes in patients with intermediate-risk, early-stage cervical cancer who underwent radical hysterectomy (RH). From cohorts two tertiary hospitals, 2009 FIGO stage IB-IIA primary RH between 2010 and 2018 were identified. Patients intermediate-risk factors that met Sedlis criteria included. Survival compared received RT (study group; n = 53) those did not receive treatment (control 30). Compared control...
Laparoscopy-assisted vaginal hysterectomy is one of the definite methods for treatment symptomatic uterine fibroids with lesser intraoperative bleeding and shorter hospitalization compared abdominal hysterectomy. However, laparoscopy-assisted cannot preserve uterus can show postoperative complications by change pelvic structure. Thus, laparoscopic artery ligation has been introduced relieving symptoms caused in place The current study was designed to compare quality life between...
Problem Dendritic cells ( DC s) play an important role in maintaining pregnancy by inducing tolerance toward the fetus. Such immunologic change mother should be restored to normal after delivery, but few studies have reported postpartum maternal immune recovery, terms of types circulating s. Method study The level each subtype and HLA ‐ DR ‐positive immunoreactivity blood from 29 pregnant women with uncomplicated labor was serially analyzed flowcytometry at delivery 1.5, 6, 12 months...
Abstract Background To determine whether additional chemotherapy after concurrent chemoradiation (CCRT) improves survival outcomes in patients with early cervical cancer who undergo radical hysterectomy (RH). Methods We included high- or intermediate-risk from two institutions, 2009 FIGO stage IB–IIA, underwent primary RH and pelvic lymphadenectomy between January 2007 June 2020, had completed adjuvant CCRT. Survival were compared received (study group) those did not (control group). Results...
Malignant melanomas of the uterus, either primary or metastatic, are extremely rare. They can be mistaken as other tumors, such uterine sarcomas during diagnosis. We describe here first case a metastatic melanoma uterus with peritoneal seeding in young woman. It was diagnosed sarcoma from frozen-section biopsy.
Pathogenesis of the endometriosis is complex and etiology still unclear. The objective this study was to examine that endometrial gene expression in late secretory phase endometrium differs between patients with without endometriosis. Five proven advanced-stage 5 controls underwent biopsy phase. Analysis eutopic performed using Affymetrix arrays differentially expressed genes were assigned ontology groups based on overrepresented analysis Database for Annotation, Visualization, Integrated...
<h3>Introduction/Background</h3> Hyperthermic intraperitoneal chemotherapy (HIPEC) during cytoreductive surgery has emerged to achieve a higher concentration of chemotherapeutic agents and treat micro-metastases on peritoneal surfaces. At advanced staged ovarian cancer treated with neoadjuvant chemotherapy, HIPEC interval cisplatin 75–100mg/m2 increases progression-free survival overall (OVHIPEC-01 KOVHIPEC-01). In chemotherapy-naïve patients, benefit is not identified (KOVHIPEC-01). And the...
TPS5635 Background: Hyperthermic intraperitoneal chemotherapy (HIPEC) during cytoreductive surgery has emerged to achieve a higher concentration of chemotherapeutic agents and treat micro-metastases on peritoneal surfaces. At advanced staged ovarian cancer treated with neoadjuvant chemotherapy, HIPEC interval cisplatin 75-100mg/m 2 increases progression-free survival overall (OV-HIPEC-01 KOV-HIPEC-01). In chemotherapy-naïve patients, benefit is not identified (KOV-HIPEC-01). And the...