A5021000774- Tuberculosis Research and Epidemiology
- Pneumocystis jirovecii pneumonia detection and treatment
- Mycobacterium research and diagnosis
- Pneumonia and Respiratory Infections
- Diagnosis and treatment of tuberculosis
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Respiratory Support and Mechanisms
- Respiratory and Cough-Related Research
- COVID-19 Clinical Research Studies
- Asthma and respiratory diseases
- Pediatric health and respiratory diseases
- Remote Sensing and Land Use
- Sepsis Diagnosis and Treatment
- Health and Wellbeing Research
- Nosocomial Infections in ICU
- SARS-CoV-2 and COVID-19 Research
- Nutrition and Health in Aging
- Remote-Sensing Image Classification
- Tracheal and airway disorders
- Acute Kidney Injury Research
- Geochemistry and Geologic Mapping
- Spacecraft and Cryogenic Technologies
- Soil and Land Suitability Analysis
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Trauma, Hemostasis, Coagulopathy, Resuscitation
Inje University Ilsan Paik Hospital
2015-2025
Inje University
2008-2023
Catholic University of Korea
2020
Chungnam National University Hospital
2020
National University College
2020
Chungbuk National University
2020
New Generation University College
2020
Pulmonary and Critical Care Associates
2017
Korea Institute of Geoscience and Mineral Resources
2011-2016
Inje University Seoul Paik Hospital
2012
Rationale: Few large-scale studies have investigated multidrug-resistant tuberculosis (MDR-TB) treatment outcomes relative to drug-resistance patterns.Objectives: To assess the impact of additional drug resistances on and long-term survival in a large HIV-negative MDR-TB cohort.Methods: Treatment patients with newly diagnosed or retreated 2000 2002 were retrospectively analyzed based patterns after 5–8 years follow-up.Measurements Main Results: Of 1,407 MDR-TB, 75 (5.3%) had extensively...
Hand grip strength (HGS) is a simple way of predicting the risk cardiovascular disease and all-cause mortality in general population. However, practical significance patients with COPD uncertain. The aim this study was to compare HGS between subjects without evaluate its clinical relevance by using national survey.Data were collected from Korean National Health Nutrition Examination Survey. included 421 adults 2,542 controls who completed questionnaires, spirometry, test. compared COPD,...
Abstract Background Screening patients with asymptomatic active tuberculosis (TB) is crucial as they can transmit the disease. Identifying risk factors for transmission essential targeted screening. Understanding how infectiousness of TB affects disease outcomes developing strategies to control spread. Methods We analyzed national Korean cohort data determine associated and clinical in pulmonary TB. The primary outcome was a factor transmission, while secondary mortality stratified by risk....
Rationale: The insulin-like growth factor-I (IGF-I) pathway is an important determinant of survival and proliferation in many cells. However, little known about the role IGF-I lung injury. We previously showed elevated levels bronchoalveolar lavage fluid from patients with acute respiratory distress syndrome. Furthermore, immunodepletion IGF syndrome increased fibroblast apoptosis.Objectives: examined effect blockade type 1 tyrosine kinase receptor (IGF-IR) a murine model bleomycin-induced...
Abstract Disparities exist between sexes regarding tuberculosis (TB) incidence, as well disease severity and outcome. Using a nationwide TB registry database, we explored the impact of sex age on extrapulmonary (EPTB) among all enrolled patients by (1) calculating female proportion for every category according to TB-affected locations, (2) proportions EPTB stratified age, (3) conducting multivariable analysis examine likelihood, (4) assessing odds compared male reference in category....
To determine the impact of sarcopenia and obesity on pulmonary function quality life (QOL) in chronic obstructive disease (COPD) patients.Data were obtained from Korea National Health Nutrition Examination Survey, including data health interviews, examinations, nutritional questionnaires, laboratory findings. Laboratory included assessment dual energy X-ray absorptiometry results. Sarcopenia was measured by absorptiometry, defined body mass index. Male COPD patients then classified into 4...
The national Public-Private Mix (PPM) tuberculosis (TB) control project provides for the comprehensive management of TB patients at private hospitals in South Korea. Surveillance and monitoring under PPM are essential toward achieving elimination goals.TB is a nationally notifiable disease Korea monitored using surveillance system. Centers Disease Control Prevention quarterly generates indicators management, used to evaluate activities by central steering committee project. Based on...
Background Chronic obstructive pulmonary disease (COPD), is a chronic inflammatory disorder. We evaluated whether white blood cell (WBC) count, associated with the severity of COPD, independent other conditions, such as metabolic syndrome. Methods The WBC counts were compared between 1227 COPD patients and 8679 non-COPD adults older than 40. relationships lung function, symptoms score in patients, determined, using general linear regression analyses. Results count was negatively forced vital...
BACKGROUND: The coronavirus disease 2019 (COVID-19) pandemic caused disruptions to healthcare systems and endangered the control prevention of tuberculosis (TB). We investigated nationwide effects COVID-19 on national Public-Private Mix (PPM) TB project in Korea, using monitoring indicators from Korean PPM database. METHODS: database includes data patients registered at hospitals throughout country. Data six for active cases updated between July June 2020 were collected. each cohort country...
Fully vaccinated people remain at risk of Coronavirus Disease 2019 (COVID-19). We examined association between prior vaccination and clinical outcomes in patients with COVID-19. Overall, 387 mild-to-severe COVID-19 were enrolled. Patients considered fully least 14, 7, 14 days after receiving the second dose ChAdOx1 nCoV-19 or mRNA-1273, BNT162b2, single Ad26.COV2.S, respectively. The primary (risk pneumonia, requirement supplemental oxygen, progression to respiratory failure) compared...
The aim of this study is to extract landslide-related factors from remote-sensing data, such as Advanced Spaceborne Thermal Emission and Reflection Radiometer (ASTER) satellite imagery, examine their applicability landslide susceptibility near Boun, Korea, using a geographic information system (GIS). Landslide was mapped interpretation aerial photographs field surveying. Factors that influence occurrence were extracted ASTER imagery. slope, aspect curvature calculated the digital elevation...
Although the incidence of tuberculosis (TB) has decreased in South Korea, mortality rate remains high. TB is a key indicator for control interventions. The purpose this study was to assess early and TB-related during anti-TB treatment describe associated clinical characteristics.A multicenter cross-sectional performed across Korea. Patients with pulmonary who died whose records were submitted national surveillance system between 2015 2017 enrolled. All deaths categorized based on cause...
The coronavirus disease 2019 (COVID-19) pandemic caused disruptions to healthcare systems, consequently endangering tuberculosis (TB) control. We investigated delays in TB treatment among notified patients during the first wave of COVID-19 Korea.We systemically collected and analyzed data from Korea cohort database January May 2020. Groups were categorized as 'before-pandemic' 'during-pandemic' based on notification period. Presentation delay was defined period between initial onset symptoms...
The Government of South Korea launched a national preemptive latent tuberculosis infection (LTBI) screening program in 2016, including more than 1. 6 million population congregate settings. objective this study was to analyze LTBI prevalence and its risk factors each setting. Additionally, the proportion pool covered by current strategy investigated. Database for results interferon gamma release assay (IGRA), X-ray, baseline demographic information linked with National Health Information...
Pulmonary rehabilitation is a multidisciplinary program of care for patients with chronic respiratory impairment that individually tailored and designed to optimize physical social performance autonomy. It can reduce symptoms, decrease disability, increase participation in activities, improve the overall quality life individuals disease. consists exercise training, patient family education, psychosocial behavioral intervention. The training should be performed at least five times per week 30...
Abstract Background Subclinical tuberculosis (TB) is a potential target for public health intervention because its early identification may reduce TB transmission. We aimed to describe the clinical and laboratory findings of subclinical disease among pulmonary patients compared treatment outcomes active diseases. Methods In this prospective cohort study, we enrolled adult aged ≥ 19 years with between 2016 2018. was defined as radiographic or microbiologic test results consistent without...
Background Chronic cough is a heterogeneous disease with various aetiologies that are difficult to determine. Our study aimed categorise the phenotypes of chronic cough. Methods Adult patients were assessed based on characteristics and severity their using COugh Assessment Test (COAT) Korean version Leicester Cough Questionnaire. A cluster analysis was performed K-prototype, variables be included determined correlation network. Results In total, 255 participants in analysis. Based network,...
Assessing the illness perception of patients with tuberculosis (TB) could improve our understanding their beliefs about disease and help address problems in health-seeking behavior.We assessed pulmonary TB association patients' demographic, socioeconomic, clinical features.Adult who were newly diagnosed at three tertiary hospitals South Korea included from November 2016 September 2018. Participants' was using Brief Illness Perception Questionnaire (BIPQ) start anti-TB treatment.In total, 390...
Abstract Tuberculosis (TB) has a heterogeneous phenotype, which makes it challenging to diagnose. Our study aimed identify TB phenotypes through cluster analysis and compare their initial symptomatic, microbiological radiographic characteristics. We systemically collected data of notified patients in Korea constructed prospective, observational cohort database. Cluster was performed using K-means clustering, the variables be included were determined by correlation network. A total 4,370...
In South Korea, public-private mix (PPM) was launched in 2011. This retrospective cohort study sought to determine the rate of loss follow-up (LTFU) among drug-susceptible tuberculosis (DS-TB) patients all nationwide PPM institutions, and risk factors for LTFU. National notification data DS-TB diagnosed between August 2011 July 2014 institutions were analysed. Determination LTFU included detection instances where transferred out, but when they did not attend at other TB centres following two...
We aimed to develop integrative machine-learning models using quantitative computed tomography (CT) parameters in addition initial clinical features predict the respiratory outcomes of coronavirus disease 2019 (COVID-19).This was a retrospective study involving 387 patients with COVID-19. Demographic, laboratory, and CT findings were used predictive outcomes. High-attenuation area (HAA) (%) consolidation defined as quantified percentages Hounsfield units between -600 -250 -100 0,...
Hospital-acquired pneumonia (HAP) and ventilator-associated (VAP) are significant public health issues in the world, but epidemiological data pertaining to HAP/VAP is limited Korea. The objective of this study was investigate characteristics, management, clinical outcomes This a multicenter retrospective cohort study. In total, 206,372 adult patients, who were hospitalized at one 13 participating tertiary hospitals Korea, screened for eligibility during six-month period. Among them, we...