A5033517259- Chronic Obstructive Pulmonary Disease (COPD) Research
- Asthma and respiratory diseases
- Respiratory Support and Mechanisms
- Pediatric health and respiratory diseases
- Respiratory and Cough-Related Research
- Health and Wellbeing Research
- Inhalation and Respiratory Drug Delivery
- Respiratory viral infections research
- Pneumonia and Respiratory Infections
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Diverse Approaches in Healthcare and Education Studies
- Delphi Technique in Research
- Chronic Disease Management Strategies
- COVID-19 Clinical Research Studies
- Air Quality and Health Impacts
- Tuberculosis Research and Epidemiology
- Emergency and Acute Care Studies
- Cystic Fibrosis Research Advances
- Health Promotion and Cardiovascular Prevention
- Lung Cancer Diagnosis and Treatment
- Pleural and Pulmonary Diseases
- Mycobacterium research and diagnosis
- Allergic Rhinitis and Sensitization
- IL-33, ST2, and ILC Pathways
- Neonatal Respiratory Health Research
Konkuk University
2016-2025
Konkuk University Medical Center
2016-2025
Catholic University of Korea
2013-2023
Seoul St. Mary's Hospital
2016-2023
Ulsan University Hospital
2023
University of Ulsan
2023
Ulsan College
2023
Hallym University Sacred Heart Hospital
2015-2022
Hallym University
2022
Boehringer Ingelheim (South Korea)
2022
Introduction: A low body mass index (BMI) is associated with increased mortality and health-related quality of life in patients COPD. The Asia-Pacific classification BMI has a lower cutoff for overweight obese categories compared to the World Health Organization (WHO) classification. present study assessed COPD among different according two systems: WHO Asia-Pacific. Patients methods: aged 40 years or older from Korean Subtype Study cohort were selected evaluation. We enrolled 1,462...
ABSTRACT Background and objective: Because the mortality social burden associated with COPD is increasing, repeated surveys of prevalence have been used to assess risk factors, detect potential patients, establish early diagnoses management protocols. We report spirometrically detected in Korea 2008, using data from fourth Korean National Health Nutrition Survey. Methods: Using nationwide stratified random sampling, based on Statistical Office census, 6840 subjects aged ≥19 years underwent...
Background: Little information is available regarding medical utilization and cost in patients with overlap syndrome of chronic obstructive pulmonary disease (COPD) asthma. The purpose this study to analyze compare them COPD without Methods: Using the 2009 Korean National Health Insurance (NHI) database, were identified. Medical costs also analyzed. Results: Of a total 185,147 identified COPD, 101,004 classified asthma 84,143 In 2009, percentages emergency room visits, admissions, intensive...
Abstract Background Gastroesophageal reflux disease (GERD) is one of the most common causes chronic cough and a potential risk factor for exacerbation obstructive pulmonary (COPD). The aim this study was to investigate prevalence factors GERD in patients with COPD association between exacerbation. Methods Data were collected from National Health Insurance Database Korea. subjects 40 years old older, who had as primary or secondary diagnosis codes utilized health care resource receive...
There has been limited evidence for the association between chronic obstructive pulmonary disease (COPD) and incidence of lung cancer among never smokers. We aimed to estimate risk in smokers with COPD, compare it associated smoking. This cohort study involved 338 548 subjects, 40 84 years age no history at baseline, enrolled National Health Insurance Service Sample Cohort. During 2 355 005 person-years follow-up (median 7.0 years), 1834 participants developed cancer. Compared without...
Abstract Background Phlegm is prevalent symptom in patients with chronic obstructive pulmonary disease (COPD). Few studies have investigated the effectiveness of N-acetylcysteine (NAC) nebulizer therapy COPD patients. We evaluated effect nebulized NAC on improvement phlegm Methods This was a 12-week, prospective, single-arm, open-label, phase IV multi-center trial (NCT05102305, Registration Date: 20-October-2021). enrolled aged ≥ 40 years post bronchodilator forced expiratory volume one...
Background Chronic obstructive pulmonary disease (COPD) is a risk factor for severe COVID-19. However, mortality after COVID-19 recovery in this population remains unclear. Methods We retrospectively enrolled individuals with COPD from the Korean National Health Insurance database. compared rate who recovered between 8 October 2020 and 31 December 2021 (COVID-19 cohort, n=2499) that 1:1 propensity score-matched controls (n=2499). The study was followed until either death or 30 September...
Multicentre study.To define the clinical characteristics of patients with tuberculosis (TB) destroyed lung due to past TB.We reviewed TB-destroyed between May 2005 and June 2011.A total 595 from 21 hospitals were enrolled. The mean age was 65.63 ± 0.47 (mean standard error); 60.5% male. number lobes involved 2.59 0.05. Pleural thickening observed in 54.1% patients. Mean forced vital capacity (FVC), expiratory volume 1 s (FEV(1)), FEV(1)/FVC, bronchodilator response exacerbations per year...
Background The ratio of neutrophils to lymphocytes (NLR) is a widely available marker inflammation. Several types inflammatory cells and mediators have been found be involved in the progression chronic obstructive pulmonary disease (COPD). We sought evaluate association NLR with severity airflow limitation exacerbations COPD population. Methods analyzed 885 patients from Korean Subtype Study cohort that recruited subjects 44 referral hospitals. determined relationship levels lung function...
Purpose:The Asia-Pacific Burden of Respiratory Diseases (APBORD) study is a cross-sectional, observational one which has used standard protocol to examine the disease and economic burden allergic rhinitis (AR), asthma, chronic obstructive pulmonary disorder (COPD), rhinosinusitis across region.Here, we report on symptoms, healthcare resource use, work impairment, associated costs in Korea.Methods: Consecutive participants aged ≥18 years with primary diagnosis AR, COPD, or were...
The Korea Chronic Obstructive Pulmonary Disorders Subgroup Study Team (Korea COPD team, KOCOSS) is a multicenter observational study that includes 956 patients (mean age 69.9 ± 7.8 years) who were enrolled from 45 tertiary and university-affiliated hospitals December 2011 to October 2014. initial evaluation for all included pulmonary function tests (PFT), 6-minute walk distance (6MWD), Assessment Test (CAT), modified Medical Research Council (mMRC) dyspnea scale, the COPD-specific version of...
The prevalence of chronic obstructive pulmonary disease (COPD) increases with age, and aging is an important risk factor for COPD development. In the era global aging, demographic information about factors associated are to establish care plans. However, limited available in rapidly societies, including Korea.We conducted a cross-sectional observational study using Korea National Health Nutrition Examination Survey data from 2015-2019. We included 15,613 participants analyzed trends...
BACKGROUND Effectiveness of biologics has neither been established in patients with high oral corticosteroid exposure (HOCS), nor compared to effectiveness continuing HOCS alone. OBJECTIVE To examine the initiating a large, real-world cohort adult severe asthma and HOCS. METHODS This was propensity-score-matched, prospective study using data from International Severe Asthma Registry (http://isaregistries.org/). Between January 2015 February 2021, (long-term OCS ≥1 year or ≥4 courses rescue...
Rationale: Levofloxacin (LFX) and moxifloxacin (MXF) are the two most frequently recommended fluoroquinolones for treatment of patients with multidrug-resistant tuberculosis (MDR-TB). However, studies comparing effectiveness LFX MXF among MDR-TB lacking.Objectives: To compare in terms culture conversion after 3 months MDR-TB.Methods: In this prospective multicenter randomized open label trial, we randomly assigned 182 (sensitive to MXF) receive either (750 mg/day; 90 patients) or (400 92 a...
The prevalence and economic burden of chronic obstructive pulmonary disease (COPD) are increasing worldwide. However, little information is available concerning COPD-associated health care use costs in Korea.To analyse 1) use, medical medication 2009, 2) changes over 5 years (2006-2010).Using the database Korean Health Insurance Review Assessment Service, COPD patients were identified by searching on both ICD-10 codes medication. RESULTS A total 192,496 2009. Total per person US$2803 ± 3865;...
The Prognostic Value of Residual Volume/Total Lung Capacity in Patients with Chronic Obstructive Pulmonary DiseaseThe prognostic role resting pulmonary hyperinflation as measured by residual volume (RV)/total lung capacity (TLC) chronic obstructive disease (COPD) remains poorly understood.Therefore, this study aimed to identify the factors related COPD and determine whether is a factor COPD.In total, 353 patients Korean Disease cohort recruited from 16 hospitals were enrolled.Resting was...
Preserved ratio impaired spirometry (PRISm) is an incompletely understood respiratory condition. We investigated the incidence and significant predictive factors of chronic obstructive pulmonary disease (COPD) in PRISm patients.From 11,922 subjects registered Korea National Health Nutrition Examination Survey, never or light smokers, young subjects, those already medically diagnosed with COPD (defined by ICD-10 code prescribed medication) were excluded. The 2666 remaining categorized into...
Abstract Preventing exacerbation in chronic obstructive pulmonary disease (COPD) patients is crucial, but requires identification of the exacerbating factors. To date, no integrated analysis patient-derived and external factors has been reported. identify associated with COPD exacerbation, we collected data, including smoking status, lung function, assessment test scores, from 594 Korean subgroup study (KOCOSS), merged these data patients’ Health Insurance Review Assessment Service for...
Purpose: Although mild to moderate asthma is much more common, the morbidity and mortality of severe are higher.This study was performed identify analyze clinical characteristics in Korea.Methods: We registered patients with refractory into Severe Asthma Registry supported by Work Group Korean Academy Asthma, Allergy Clinical Immunology.Patients were enrolled since 2010 from 15 university hospitals nationwide Korea.Severe defined according modified European Respiratory Society/American...
ABSTRACT Background and objective The global burden of chronic obstructive pulmonary disease (COPD) is increasing COPD patients are at higher risk for all‐cause mortality. We aimed to evaluate the impact on specific‐cause mortality using national data. Methods This was nationwide retrospective cohort study 340, 767 adults aged 40–84 years who lacked diagnosis baseline between 1 January 2003 31 December 2013. Incident defined by reference claim codes prescription medication least twice...
Purpose: Asthma is a common disease that expensive and burdensome for patients.Inhaled corticosteroids (ICS) are the most important drugs asthma treatment often prescribed long-term.However, use of ICS has been reported to increase pneumonia, though this remains controversial.We evaluated whether increases risk pneumonia in asthmatic patients using Health Insurance Review Assessment Service (HIRA) database Korea.Methods: The Management Adequacy was performed by HIRA Korea.Patients with...