A5062697720- Chronic Obstructive Pulmonary Disease (COPD) Research
- Respiratory Support and Mechanisms
- Asthma and respiratory diseases
- COVID-19 Clinical Research Studies
- Cystic Fibrosis Research Advances
- Inhalation and Respiratory Drug Delivery
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Respiratory and Cough-Related Research
- Neonatal Respiratory Health Research
- Sepsis Diagnosis and Treatment
- Tuberculosis Research and Epidemiology
- Emergency and Acute Care Studies
- Mycobacterium research and diagnosis
- Long-Term Effects of COVID-19
- Gastroesophageal reflux and treatments
- Pediatric health and respiratory diseases
- Esophageal and GI Pathology
- Palliative Care and End-of-Life Issues
- Lung Cancer Diagnosis and Treatment
- COVID-19 and healthcare impacts
- Tracheal and airway disorders
- Family and Patient Care in Intensive Care Units
- Helicobacter pylori-related gastroenterology studies
- Intensive Care Unit Cognitive Disorders
- Pulmonary Hypertension Research and Treatments
Konkuk University Medical Center
2008-2025
Konkuk University
2022-2024
Catholic University of Korea
2012-2023
Seoul St. Mary's Hospital
2023
Hallym University Sacred Heart Hospital
2022
Chuncheon Sacred Heart Hospital
2018-2021
Hallym University
2018-2021
Kyoto University
2021
Seoul National University Bundang Hospital
2017-2020
Hallym University Medical Center
2019
Pyrazinamide (PZA) is a common drug that causes serious adverse events (SAEs). The aim of this study was to determine the incidence and risk factors for SAEs due PZA during first-line anti-tuberculosis treatment.The medical records patients with tuberculosis (TB) treated PZA-containing regimens including drugs-ethambutol, rifampicin, isoniazid-from January 2003 June 2016 were reviewed. defined as side effects led discontinuation. causative determined based on disappearance upon withdrawal...
Abstract There are limited data regarding whether mortality is higher in patients with non cystic fibrosis bronchiectasis (bronchiectasis) than those without bronchiectasis. Using 2005–2015 from the Korean National Health Insurance Service, we evaluated hazard ratio (HR) for all-cause cohort relative to matched cohort. The effect of comorbidities over study period on was also assessed. All-cause significantly (2505/100,000 vs 2142/100,000 person-years, respectively; P < 0.001). Mortality...
Rationale: It remains unclear whether non-cystic fibrosis bronchiectasis increases the risk of lung cancer, because smoking history was not considered in previous studies. Objectives: To evaluate participants with have a higher incident cancer than those without information on status. Methods: This population-based cohort study 3,858,422 individuals who participated 2009 National Health Screening Program. We evaluated incidence (n = 65,305) and 3,793,117). followed up until date diagnosis,...
The prevalence of chronic obstructive pulmonary disease (COPD) increases with age, and aging is an important risk factor for COPD development. In the era global aging, demographic information about factors associated are to establish care plans. However, limited available in rapidly societies, including Korea.We conducted a cross-sectional observational study using Korea National Health Nutrition Examination Survey data from 2015-2019. We included 15,613 participants analyzed trends...
Despite the importance of comorbid ischemic heart disease (IHD) in prognosis asthma, long-term impact coronavirus 2019 (COVID-19) on IHD adults with asthma remains unclear. This study investigated effects COVID-19 risk individuals particularly regarding severity. Using Korean National Health Insurance Service claims database, we identified who had recovered from between October 8, 2020, and December 31, 2021 (n = 8,011) 1:1 propensity score-matched controls 8,011). The incidence were...
Computed tomography (CT) scans are used to assess emphysema, a significant phenotype of chronic obstructive pulmonary disease (COPD), but variability in CT protocols and devices across the hospitals may affect accuracy. This study aims perform kernel conversion among different settings evaluate differences correlation between emphysema index before after conversion, as well clinical measures COPD patients. The data were extracted from Korea Subgroup Study database, involving 484 patients...
Background Chronic obstructive pulmonary disease (COPD) is a risk factor for severe COVID-19. However, mortality after COVID-19 recovery in this population remains unclear. Methods We retrospectively enrolled individuals with COPD from the Korean National Health Insurance database. compared rate who recovered between 8 October 2020 and 31 December 2021 (COVID-19 cohort, n=2499) that 1:1 propensity score-matched controls (n=2499). The study was followed until either death or 30 September...
Coronavirus 2019 (COVID-19) vaccination appears to have potential benefits for patients with chronic obstructive pulmonary disease (COPD). However, limited information is available on whether COVID-19 reduces acute exacerbation of COPD (AECOPD). In the present study, 41,606 individuals were enrolled using Korean National Health Insurance System-severe respiratory syndrome coronavirus 2 (NHIS SARS-CoV-2) database from 2020-2021. A total 3,602 included in analytical cohort through 1:1...
Abstract Background Chronic obstructive pulmonary disease (COPD) is associated with severe Coronavirus 2019 (COVID-19) outcomes. However, it uncertain whether the risk of acute exacerbation COPD (AECOPD) increases after recovering from COVID-19. Methods This study included 2,118 individuals Korea National Health Insurance Service database who were also diagnosed Matched controls chosen using 1:1 propensity score (PS) matching. We compared AECOPD COVID-19 recovery between cohort and matched...
[Purpose] The objective of this study was to investigate the effects mirror therapy combined with exercise tasks on function upper limbs and activities daily living. [Subjects Methods] Twenty-five stroke patients who were receiving physical at K Hospital in Gyeonggi-do, South Korea, classified into a group (n=12) conventional (n=13). therapies applied for 30 minutes per day, five times week, total four weeks. Upper limb measured Action Research Arm test, Fugl-Meyer Assessment, Box Block...
To evaluate the effect of a part-time rapid response system on occurrence rate cardiopulmonary arrest by comparing times operation versus nonoperation.Retrospective cohort study.A 1,360-bed tertiary care hospital.Adult patients admitted to general ward were screened. Data collected over 36 months from implementation (October 2012 September 2015) and more than 45 before (January 2009 2012).None.The operates 7 AM 10 PM weekdays 12 Saturdays. Primary outcomes difference incidence between...
Introduction Despite the significant disease burden of bronchiectasis in Korea, no large-scale, representative prospective cohort studies have been conducted to evaluate clinical characteristics Korean patients with bronchiectasis, indicating an urgent need for on bronchiectasis. Methods and analysis The Multicenter Bronchiectasis Audit Research Collaboration (KMBARC) is a prospective, non-interventional observational study Korea. inclusion criteria this registry are as follows: (1) adult...
Background: Comorbidities of chronic obstructive pulmonary disease (COPD) influence clinical characteristics and prognosis. Objectives: This study compared the exacerbation rate COPD according to presence depression or anxiety. Design: used data from The Korea Subgroup Study (KOCOSS) cohort, a nationwide prospective cohort 54 medical centers, between April 2012 2019. Methods: Depression anxiety were diagnosed with Beck Inventory Anxiety Inventory. Negative binomial regression analysis was...
Few studies have directly compared the incidence of pneumonia in patients on common chronic obstructive pulmonary disease (COPD) treatments such as long-acting muscarinic antagonists (LAMA) with those inhaled corticosteroids and β2-agonist (ICS/LABA). Moreover, risk factors for COPD are still unclear. We aimed to compare LAMA ICS/LABA explored associated pneumonia. This nationwide cohort study used Korean National Health Insurance claim data from January 2002 April 2016. Patients who...
Conventional hard or dynamic wedge systems are commonly applied to reduce the dose inhomogeneity associated with whole breast irradiation. We evaluated dosimetric benefits of field-in-field (FIF) technique by comparing it electronic compensator (EC), Varian enhanced (EW) and conventional (HW) techniques. Data were obtained from 12 patients who had undergone breast-conserving surgery (six left-sided six right-sided). For these patients, average planning target volume (PTV) was 447.4 cm(3)...
Efforts to detect patient deterioration early have led the development of warning score (EWS) models. However, these models are disease-nonspecific and shown variable accuracy in predicting unexpected critical events. Here, we propose a simpler more accurate method for risk respiratory ward patients. This retrospective study analyzed adult patients who were admitted detected using rapid response system (RRS). Study outcomes included transfer intensive care unit (ICU) within 24 hours after...
Air trapping is a predictive index for decline in lung function and mortality patients with chronic obstructive pulmonary disease (COPD). However, the role of air COPD exacerbation has rarely been studied. Therefore, this study aimed to investigate impact as continuous parameter on exacerbation.To evaluate trapping, we identified ratio residual volume (RV) total capacity (TLC) from Korean Subgroup Study (KOCOSS) cohort, which multicenter-based, prospective, consecutive cohort Korea. The...
Although family satisfaction is an important indicator for quality improvement of intensive care units (ICUs), few studies have translated data into in Asia. A prospective multicenter study was conducted to evaluate regarding the patients and their family.The ICU (FS-ICU) questionnaire administered from January 2015 February 2016 at ICUs 3 tertiary teaching hospitals South Korea. Family members adult patients, staying ≥48 hours, were included. Key factors affecting identified using...
Abstract With the increasing use of computed tomography, bronchiectasis has become a common finding in patients with chronic obstructive pulmonary disease (COPD). However, clinical aspects and medical utilization COPD (BE) remain unclear. We aimed to investigate BE effect on prognosis COPD. Among 263,747 patients, we excluded lacking chest X-ray, CT, or function test codes classified 2583 GOLD-C/D matched according age, sex, aid as having COPD-BE (447 [17.3%]) without (2136 [82.7%])....
BackgroundDifferent progressions or prognoses of chronic obstructive pulmonary disease (COPD) have been reported according to structural abnormalities based on chest computed tomography (CT). This study aimed investigate whether different independently affect annual lung function changes and clinical prognosis in patients with COPD.MethodsThis longitudinal multicenter observational was conducted using the KOCOSS cohort (NCT02800499) database Korea from January 2012 December 2019. For COPD CT...
A suboptimal peak inspiratory flow rate (PIFR) in dry-powder inhaler (DPI) users can lead to insufficient therapeutic effects the treatment of chronic obstructive pulmonary disease (COPD). However, few data on prevalence and factors associated with PIFR Korean patients COPD are available.
Candidates for preoperative or intraoperative nodal assessment among patients with non-small cell lung cancer (NSCLC) manifesting as a subsolid tumor are not established. The present study was conducted to demonstrate the distribution of metastasis rate according newly proposed T categories tumors, and we further aimed identify radiologic parameters that can be predictive metastasis. We retrospectively reviewed cases NSCLC in computed tomography scans university-affiliated tertiary hospital...