A5103244978- Allergic Rhinitis and Sensitization
- Asthma and respiratory diseases
- Food Allergy and Anaphylaxis Research
- Contact Dermatitis and Allergies
- Analytical Methods in Pharmaceuticals
- Drug-Induced Adverse Reactions
- Dermatology and Skin Diseases
- Occupational exposure and asthma
- Pharmacogenetics and Drug Metabolism
- Antibiotics Pharmacokinetics and Efficacy
- Respiratory and Cough-Related Research
- Pharmacological Effects and Toxicity Studies
- Estrogen and related hormone effects
- Diabetes Treatment and Management
- Cancer Treatment and Pharmacology
- Blood Pressure and Hypertension Studies
- Travel-related health issues
- Lipoproteins and Cardiovascular Health
- Biosimilars and Bioanalytical Methods
- Indoor Air Quality and Microbial Exposure
- Hepatitis C virus research
- Pediatric health and respiratory diseases
- Pharmacovigilance and Adverse Drug Reactions
- Computational Drug Discovery Methods
- Sexual function and dysfunction studies
Inha University Hospital
2013-2023
Seoul National University
2011-2021
Seoul National University Hospital
2011-2021
New Generation University College
2001-2018
Cohen Children's Medical Center
2018
National University College
2014
Inha University
2014
Republic of Korea Army
2012
University of Ulsan
2009-2012
Asan Medical Center
2009-2012
Purpose:The Asia-Pacific Burden of Respiratory Diseases (APBORD) study is a cross-sectional, observational one which has used standard protocol to examine the disease and economic burden allergic rhinitis (AR), asthma, chronic obstructive pulmonary disorder (COPD), rhinosinusitis across region.Here, we report on symptoms, healthcare resource use, work impairment, associated costs in Korea.Methods: Consecutive participants aged ≥18 years with primary diagnosis AR, COPD, or were...
Some western countries recently have shown a slowdown in the incidence of allergic diseases after worldwide increasing trends, but there are few data from Asian populations concerning changing trend diseases. We evaluated recent trends prevalence asthma and other Korea.From database Korean National Health Insurance, nationwide diagnostic 2009 to 2014 were extracted national was analyzed.The per 1000 people atopic dermatitis, rhinitis, 19.0, 133.1, 36.3, respectively. The three highest age...
ABSTRACT Background and objective: Reactivation of hepatitis B virus (HBV) is thought to be associated with immunosuppressive treatments, but insufficient information available on the effect corticosteroids. The aim this study was evaluate risk HBV reactivation in surface antigen‐seropositive patients asthma or COPD, who were treated systemic corticosteroids (SCS) addition inhaled (ICS). Methods: Patients COPD ( n = 198), had been ICS, identified retrospectively. To additional effects SCS,...
sal congestion, the most common symptom, and long-term use can lead to weight gain in some patients.Thus, patients who do not want receive such medication often seek complementary alternative therapies effects of which have yet been verified.Ginseng has long used as an herbal throughout East Asia, including Korea, is a member scientific family Araliaceae, genus Panax.Of species ginseng,
Purpose: Evogliptin (DA-1229) is a novel, potent, and selective dipeptidyl peptidase IV (DPP-IV) inhibitor in clinical development for the treatment of type 2 diabetes mellitus. This study aimed to investigate pharmacokinetic pharmacodynamic profiles tolerability evogliptin after repeated oral administration healthy subjects. Patients methods: A block-randomized, double-blind, placebo-controlled, multiple-dose, dose-escalation was performed total 30 Repeated once-daily doses 5, 10, or 20 mg...
children.The application of limited number allergens could be possible for patients since the rate sensitization to some is quite low and differs based on age.This an important concept when epidemiologic study required.Knowledge composition minimally required SPT panel difference dependent age essential factor a reliable survey.A recent Global Allergy Asthma European Network demonstrated patterns different
Objective The effects of various polymorphisms in cytochrome P450 (CYP) enzyme and transporter genes on the pharmacokinetics (PK) simvastatin were evaluated healthy Korean men. Methods Plasma concentration data for acid pooled from four phase I studies comprising 133 participants. CYP2D6*4, CYP2D6*5, CYP2D6*14, CYP2D6*41, CYP3A5*3, CYP2C19*2, CYP2C19*3, CYP2A6*7, CYP2A6*9; SLCO1B1 rs4149056, rs2306283, rs4149015; ABCB1 rs1128503, rs2032582, rs1045642; ABCG2 rs2231142 each participant....
The cardio-ankle vascular index (CAVI) reflects overall arterial stiffness from the aorta to ankle, independent of blood pressure. Cerebral small vessel diseases (SVDs), including white matter lesions (WML), silent lacunar infarction (SLI) and cerebral microbleeds (CMB), are considered increase risk stroke cognitive impairment further. We aimed investigate association SVD with CAVI in asymptomatic young middle-aged subjects.Asymptomatic Korean individuals aged 30 59 years old without...
Oral allergy syndrome (OAS) is a type of allergic reaction that mainly occurs on oral contact with raw fruit, vegetables, or nuts. The most common OAS birch pollen-related food allergy. Although in adults, only few epidemiologic studies have been reported Korea. Here we investigate the prevalence and triggers allergy.We conducted retrospective chart review 1,427 patients who underwent skin prick test for inhalant allergens at Asthma Allergy Clinic Seoul National University Bundang Hospital...
Background: Although airway hyperresponsiveness (AHR) is a characteristic feature of asthma, it also frequently present in allergic rhinitis (AR). However, the pathogenesis AHR unclear and roles cytokines have not been well established AR. We sought to compare cytokine mRNA levels sputum AR patients with or without those asthma patients, evaluate whether differences are associated development an abnormal response absence respiratory symptoms AHR. Methods: Airway cells were obtained by...
Objective Tissue eosinophilia is a hallmark of nasal polyposis. However, there no universally accepted definition for eosinophilic polyp. The aims this study were to histologically analyze the inflammatory cell population in polyp and propose concept allergic (EAP), simple objective that would be clinically practically valuable. Study Design A cohort with histological analysis tissue sections chart review. Setting tertiary university hospital. Subjects Methods Nasal tissues harvested during...
Food-dependent exercise-induced anaphylaxis (FDEIA) is a type of associated with postprandial exercise. We describe 19-year-old man FDEIA. Our patient complained urticaria, angioedema, dizziness and hypotension exercise after ingestion walnut-containing foods in warm environment. Skin prick test to were positive for walnut antigen. The attack didn't occur by free running outside 10 min 2 h taking walnuts, the temperature was about -2°C. Food-exercise done again environment based on prior...
Childhood allergies are a serious problem, as they may lead to lifetime chronic disease. Determination of total and specific IgE levels is known be diagnostic tool for allergic sensitization; however, affected by various factors, such age, sex, ethnicity, geographic area. Thus, we evaluated the distribution serum against seven inhalant allergens in preschool children examined their association with diseases Seoul, Korea. Total/specific determination skin prick tests common were performed on...
they have no asthmatic symptoms. 6,7rior studies reported an association between the specific aeroallergen sensitization and development of asthma or AHR.Sensitization to house dust mite mold was associated with increasing asthma. 8Cockroach allergy also has been as important cause 9There a trend in AHR increased cat allergen exposure. 10However, pollen not significantly presence symptoms AHR. 11revious generally focused on prevalence
High doses of vancomycin increase the risk nephrotoxicity, but quantitative relationship between exposure and nephrotoxicity is still controversial. This study evaluated trough concentration factors for in patients undergoing therapeutic drug monitoring.A total 1269 cases from who underwent monitoring were collected 2006 to 2010. Receiver operating characteristic curve analysis was used evaluate incidence nephrotoxicity. Logistic regression using generalized Least Absolute Shrinkage...