A5100668096- Asthma and respiratory diseases
- Allergic Rhinitis and Sensitization
- Dermatology and Skin Diseases
- Immune Response and Inflammation
- Pediatric health and respiratory diseases
- Contact Dermatitis and Allergies
- Immunotherapy and Immune Responses
- Ocular Surface and Contact Lens
- Respiratory and Cough-Related Research
- Adrenal and Paraganglionic Tumors
- Periodontal Regeneration and Treatments
- Osteoarthritis Treatment and Mechanisms
- Antimicrobial Peptides and Activities
- Growth Hormone and Insulin-like Growth Factors
- Pituitary Gland Disorders and Treatments
- Proteoglycans and glycosaminoglycans research
Seoul National University
2009-2021
Seoul National University Hospital
2013
Sensory (United States)
2012
New Generation University College
2012
The University of Tokyo
2009
The eye is protected by the ocular immunosurveillance system. We show that tear duct-associated lymphoid tissue (TALT) located in mouse lacrimal sac and shares immunological characteristics with mucosa-associated tissues (MALTs), including presence of M cells immunocompetent for antigen uptake subsequent generation mucosal immune responses against ocularly encountered antigens bacteria such as Pseudomonas aeruginosa. Initiation TALT genesis began postnatally; it occurred even germ-free...
children.The application of limited number allergens could be possible for patients since the rate sensitization to some is quite low and differs based on age.This an important concept when epidemiologic study required.Knowledge composition minimally required SPT panel difference dependent age essential factor a reliable survey.A recent Global Allergy Asthma European Network demonstrated patterns different
It remains unknown whether local inhibition of Nuclear factor-kappa B (NF-κB) could have therapeutic value in the treatment allergic rhinitis (AR). This study aimed to evaluate effect selective NF-κB using decoy oligodeoxynucleotides (ODNs) for AR ovalbumin (OVA)-sensitized wild-type mice. BALB/c mice were sensitized with OVA and alum, then challenged intranasally OVA. ODNs given group, scrambled sham group. Allergic symptom scores, eosinophil infiltration, cytokine levels nasal mucosa,...
This study investigated the long-term efficacy, safety, and compliance associated with sublingual immunotherapy (SLIT) in Korean patients allergic rhinitis sensitized to house dust mites.This is a retrospective cohort study. A total of 164 who were Dermatophagoides pteronyssinus farinae received SLIT enrolled between November 2007 January 2010. Each patient was followed up using diary card, on which symptom score, rescue medication adverse events (AEs) recorded.All symptoms improved after 3...
Although long-term dopamine agonist (DA) therapy is recommended as a first-line treatment for prolactinoma, some patients may prefer surgical because of the potential adverse effects medication, or desire to become pregnant. This study aimed determine whether prolactinomas could be an alternative DA therapy.In this retrospective study, 96 consecutive (74 female, 22 male) underwent primary pituitary surgery without at single institution from 1990 2010. All in microscopic transsphenoidal...
Conclusion: The results of this study suggest that staphylococcal enterotoxin B (SEB) enhances inflammation in allergic rhinitis (AR) and interleukin (IL)-17 may play a significant role regulation the inflammatory process induced by SEB. Objectives: Exposure to SEB is associated with severe symptoms AR patients. However, how influences has not been elucidated so far. aim was identify IL-17 AR. Methods: BALB/c IL-17-deficient mice were divided into three groups: control, OVA, groups. control...
Background Bilateral mucoperichondrial flap elevation is often needed to properly correct the septal deformity although it has been discouraged because of possible complications. This study investigated effect unilateral versus bilateral on morphological and histological changes cartilage in a rabbit model. Methods Eighteen mature New Zealand white rabbits were categorized into three groups (six animals for each) according procedures they received: no elevation. In each group, one-half...