A5074538874- Head and Neck Cancer Studies
- Thyroid Cancer Diagnosis and Treatment
- Salivary Gland Tumors Diagnosis and Treatment
- Genetic factors in colorectal cancer
- Voice and Speech Disorders
- Lung Cancer Treatments and Mutations
- Head and Neck Surgical Oncology
- Tracheal and airway disorders
- Ear and Head Tumors
- Hippo pathway signaling and YAP/TAZ
- Thyroid and Parathyroid Surgery
- Dysphagia Assessment and Management
- Retinal Diseases and Treatments
- Cancer-related gene regulation
- Head and Neck Anomalies
- Oral and Maxillofacial Pathology
- Cancer Genomics and Diagnostics
- Gastric Cancer Management and Outcomes
- Radiomics and Machine Learning in Medical Imaging
- Cancer Diagnosis and Treatment
- Reconstructive Surgery and Microvascular Techniques
- Airway Management and Intubation Techniques
- Helicobacter pylori-related gastroenterology studies
- Mycobacterium research and diagnosis
- Retinal and Macular Surgery
Seoul National University Bundang Hospital
2016-2025
Seoul National University
2005-2025
Chungbuk National University
2025
Kyung Hee University
2022-2024
Chonnam National University Hospital
2024
Gyeongsang National University
2024
Inha University
2020-2023
Dong-A University
2009-2023
National University College
2013-2023
New Generation University College
2007-2023
This study explores the feasibility of creating a pneumatically driven soft gripper using Thermoplastic Polyurethane (TPU) through Direct Ink Writing (DIW) technology via heated syringe extrusion process. Unlike traditional DIW methods that do not involve heating, this approach allows for heat-sensitive materials like TPU, thereby broadening potential applications additive manufacturing. The was designed based on prior research, and key fabrication parameters—such as temperature, pneumatic...
Background: Active surveillance (AS) is an alternative to thyroidectomy for the management of low-risk papillary thyroid microcarcinoma (PTMC). However, prospective AS data collected from diverse populations are needed. Methods: This multicenter cohort study enrolled patients three referral hospitals in Korea. The participants were self-assigned into two groups, or immediate surgery. All underwent neck ultrasound every 6–12 months monitor disease progression. Progression under was evaluated...
Background: In this ongoing multicenter prospective cohort study on active surveillance (AS) in low-risk papillary thyroid microcarcinoma (PTMC), we aimed to compare the quality of life (QoL) participants based their choice treatment, that is, AS or immediate surgery (OP). Methods: QoL 203 who chose and 192 underwent OP was evaluated using a thyroid-specific questionnaire at diagnosis during follow-up (median 8 months). Results: The mean ages groups were 47.3 ± 11.7 45.6 10.5 years (p =...
IMPORTANCE Classically, surgery has been the mainstay of management for vocal fold (VF) polyps. However, a significant portion patients experience spontaneous regression and may not require surgery. OBJECTIVES To report results conservative VF polyps, identify with polyps that are more likely to resolve, describe time course resolution. DESIGN, SETTING, AND PARTICIPANTS In this case series 248 conducted presenting tertiary referral center, 94 were treated conservatively at least 3 months...
BACKGROUND “Atypia of undetermined significance” (AUS) in the Bethesda System for Reporting Thyroid Cytopathology is a heterogeneous category cases that cannot be easily classified into benign, suspicious, or malignant. This study evaluated whether cytomorphology‐based subcategorization could better predict malignancy risk designated as AUS, and how subcategories correlated with BRAF mutation status thyroid fine‐needle aspirates (FNA). METHODS Of 3589 FNA diagnosed at authors' institution...
Immune escape of a tumor from tumor-infiltrating lymphocytes (TILs) is induced by PD-L1, which suppressed miR-197. We investigated the clinicopathologic implications miR-197/PD-L1 axis and its effects on TILs features oral squamous cell carcinoma (OSCC). used RT-PCR immunohistochemistry in 68 OSCC patients to analyze correlations between tumoral expression miR-197 PD-L1 degree invasion (CD3+, CD4+, CD8+, PD-1+, FoxP3+, CD20+ lymphocytes). levels correlated inversely with but positively TILs....
The ongoing Multicenter Prospective Cohort Study of Active Surveillance on Papillary Thyroid Microcarcinoma (MAeSTro) aims to observe the natural course papillary thyroid microcarcinoma (PTMC), develop a protocol for active surveillance (AS), and compare long-term prognosis, quality life, medical costs between AS immediate surgery groups.This multicenter prospective cohort study PTMC started in June 2016. inclusion criteria were suspicious malignancy or based fine needle aspiration core...
This research presents a comprehensive comparative analysis of SLAM algorithms and Deep Neural Network (DNN)-based Behavior Cloning (BC) navigation in outdoor agricultural environments. The study categorizes into laser-based vision-based approaches, addressing the specific challenges posed by uneven terrain similarity between aisles an orchard farm. DNN-based BC technique proves efficient, exhibiting reduced human intervention providing viable alternative for navigation. Despite approach...
BackgroundActive surveillance (AS) has emerged as a viable management strategy for low-risk papillary thyroid microcarcinoma (PTMC), following pioneering trials at Kuma Hospital and the Cancer Institute in Japan. Numerous prospective cohort studies have since validated AS option PTMC, leading to its inclusion cancer guidelines across various countries. From 2016 2020, Multicenter Prospective Cohort Study of Active Surveillance on Papillary Thyroid Microcarcinoma (MAeSTro) enrolled 1,177...
Wearable electronics require stretchable displays that can withstand large and repeated mechanical deformation without failure. Intrinsically organic light-emitting diodes (ISOLEDs) operate under DC voltage provide promising candidates for wearable display applications. However, the lack of sophisticated materials processing techniques suitable ISOLEDs results in a significant deficit efficiency state-of-the-art compared to industrial standards. The design conducting semiconducting poses...
In this study, we demonstrate that hyphal differentiation is induced by the subtoxic concentration of exogenous H(2)O(2) in Candida albicans. This finding confirmed changing intracellular H(2)O(2). order to induce same level differentiation, low concentrations are required for null mutants thiol-specific antioxidant and catalase, while higher needed cells treated with ascorbic acid, an chemical.
Carcinoma ex pleomorphic adenoma (CXPA) arises from the primary or recurrent benign adenoma. The purpose of this study was to evaluate clinical features that could be referenced in differentiation. medical records 221 patients with and 15 CXPA were retrospectively reviewed. Clinical characteristics, computed tomography magnetic resonance imaging findings, surgical pathology analyzed. Patients older (55.1 vs 42.3; P < .01). observed at higher rates minor salivary glands (24.9% 2.7%)...
Abstract Context The long-term quality of life (QoL) in patients with low-risk papillary thyroid microcarcinoma (PTMC) underwent active surveillance (AS) and immediate surgery is unclear. Objective aim this study was to investigate the effect initial treatment choice on 2-year QoL PTMC Design, Setting, Participants We analyzed 2652 surveys from 1055 subjects enrolled ongoing multicenter prospective cohort PTMC, which median follow-up duration 24.4 months. Major Outcome Measure evaluated...
The increased mitochondrial DNA damage leads to altered functional capacities of retinal pigment epithelial (RPE) cells. A previous study showed the autophagy in RPE cells caused by low concentrations rotenone, a selective inhibitor complex I. However, mechanism which regulates cell death is still unclear. In present study, we examined underlying regulation through inhibition We report herein that rotenone induced mitotic catastrophe (MC) further observed an level undergoing MC (RPE-MC...
Background: Altered microRNA expression is associated with cancer progression. This study investigated the prognostic significance of microRNA-155-5p (miR-155-5p), a well-known oncomiR, in oral squamous cell carcinoma (OSCC). Materials and Methods: miR-155-5p was assessed using quantitative reverse-transcription polymerase chain reaction 68 formalin-fixed, paraffin-embedded OSCC specimens. E-Cadherin immunohistochemistry conducted to correlate epithelial–mesenchymal transition (EMT)...
Abstract Background Distant metastasis of adenoid cystic carcinoma (ACC) is most commonly identified in the lung, but risk factors are still on debate. Methods Risk for lung were evaluated by using Cox proportional hazards model and Kaplan–Meier curves. Results Of 112 patients, 48% had distant metastasis; 94.4% whom metastasis. Univariable analysis revealed sublingual or minor salivary gland, tumor size ≥2.5 cm, perineural invasion as (hazard ratio [HR]: 1.99 [1.02–3.91], 2.57 [1.19–5.58],...
Abstract Temporalis muscle thickness (TMT) on brain magnetic resonance imaging (MRI) is correlated with sarcopenia and can be a predictive marker for survival in patients tumors, but the association of TMT head neck computed tomography (CT) squamous cell carcinoma (HNSCC) remains unclear. We investigated whether CT could predict progression-free (PFS) HNSCC. A total 106 newly diagnosed HNSCC were included this retrospective study. The underwent baseline and/or MRI between July, 2008 August,...
Background: Active surveillance (AS) is offered as a choice to patients with low-risk papillary thyroid microcarcinoma (PTMC). This study aimed identify patient and physician factors associated the of AS. Methods: We conducted cross-sectional survey PTMC who were enrolled in prospective comparing outcomes following AS surgery. Patients completed questionnaire assess their prior knowledge disease, considerations decision-making process, reasons for choosing treatment. also surveyed 19...