- Anesthesia and Pain Management
- Anesthesia and Neurotoxicity Research
- Nausea and vomiting management
- Cancer, Stress, Anesthesia, and Immune Response
- Anesthesia and Sedative Agents
- Barrier Structure and Function Studies
- Proteoglycans and glycosaminoglycans research
- Pain Mechanisms and Treatments
- Trigeminal Neuralgia and Treatments
- Pain Management and Opioid Use
- Nanoplatforms for cancer theranostics
- Gut microbiota and health
- Cardiac, Anesthesia and Surgical Outcomes
- Fibroblast Growth Factor Research
- Acupuncture Treatment Research Studies
- Otolaryngology and Infectious Diseases
- Pain Management and Treatment
- Intracranial Aneurysms: Treatment and Complications
- Migraine and Headache Studies
- Vibrio bacteria research studies
- Infant Nutrition and Health
- Antimicrobial Peptides and Activities
- Traumatic Brain Injury and Neurovascular Disturbances
- Ultrasound in Clinical Applications
- Oropharyngeal Anatomy and Pathologies
Chungnam National University
2017-2021
Cleveland Clinic
2016-2020
Chungnam National University Hospital
2019
National University College
2019
New Generation University College
2019
Case Western Reserve University
2017
Cleveland Clinic Lerner College of Medicine
2014-2015
Kangbuk Samsung Hospital
2010
Sungkyunkwan University
2010
In this study, we demonstrate that hyphal differentiation is induced by the subtoxic concentration of exogenous H(2)O(2) in Candida albicans. This finding confirmed changing intracellular H(2)O(2). order to induce same level differentiation, low concentrations are required for null mutants thiol-specific antioxidant and catalase, while higher needed cells treated with ascorbic acid, an chemical.
Background and objectives: There are several studies that sevoflurane could enhance proliferation of cancer cells, while others suggest no effect on clinical outcome. We conducted in vivo vitro experiments to investigate the effects sevoflurane, a volatile anesthetic, outcomes Lewis lung carcinoma (LLC) cells. Materials Methods: A total 37 mice were injected with LLC cells compare tumor size survival exposed group (sevo group) control group. The sevo was 2% 4 L/min oxygen for 1 h per day 3...
Abstract Background Intravenous anesthesia has been reported to have a favorable effect on the prognosis of cancer patients. This study was performed analyze data regarding relation between anesthetics and patients in our hospital. Methods The medical records who underwent surgical resection for gastric, lung, liver, colon, breast January 2006 December 2009 were reviewed. Depending type anesthetic, it divided into total intravenous (TIVA) or volatile inhaled (VIA) group. 5-year overall...
The addition of the adjuvant dexmedetomidine to a nerve block improves quality and reduces perioperative opioid consumption. aim this study was assess effect as an for thoracic paravertebral (TPVB) in postoperative pain control after video-assisted thoracoscopic surgery (VATS).Sixty-six males, aged 15⁻40 years, with spontaneous pneumothorax scheduled VATS wedge resection were enrolled. Following surgery, ultrasound-guided TPVB performed on T3 T5 levels 30 mL 0.5% ropivacaine, plus 50 μg or...
Nuclear factor of activated T cells (NFAT5) is a well-known transcription that regulates the expression genes involved in osmotic stress. However, role NFAT5 inflammatory pain remains unknown. Here, we studied function using NFAT5-heterozygous (Het) mice. To study pain, injected 10 µL 2% formalin into right hind paws mice and monitored behaviors, such as licking, lifting, flinching, for 60 min. After first 15 min (phase I), there were no significant differences behaviors between wild-type...
Objective Although opioids may induce nausea and vomiting, they possess sedative effects can reduce intraoperative vomiting (IONV). This study assessed the effect of adding fentanyl to midazolam on sedation levels IONV during cesarean section under spinal anesthesia. Methods Eighty parturients scheduled for elective were enrolled in study. Following fetal delivery, patients administered 0.05 mg/kg plus 0.03 mL/kg normal saline (M group) or 1.5 μg/kg (MF group). The primary outcome was...
Although the loop electrosurgical excision procedure (LEEP) is a brief procedure, it can cause severe pain and discomfort to patients in absence of adequate sedation. An admixture ketamine with propofol (ketofol), may reduce patient movement due insufficient sedation while providing hemodynamic respiratory stability. This study evaluated ability two ratios propofol-ketamine combination, compared alone, during procedural for LEEPs.One hundred twenty women scheduled LEEP were randomly assigned...
Background: Thoracic interfascial plane block is useful as a component of multimodal analgesia in patients undergoing mastectomy. However, tends not to be provided during lumpectomy it one the less aggressive procedures among breast cancer surgeries. Therefore, we investigated effects thoracic more effective after lumpectomy. Methods: Forty six (20-80 years old, female) with scheduled undergo were randomly assigned two groups. Postoperative pain control group consisted only intravenous...
Iatrogenic vascular injury during lumbar disc surgery is a rare but serious complication. This paper reports patient who sustained an to the iliac artery while undergoing intervertebral at region. He suffered from massive bleeding and shock. An urgent laparatomy was performed under cardiopulmonary bypass, injuries were repaired successfully. case shows that rapid diagnosis immediate intervention can result in favorable outcome. Keywords: Discectomy; Iatrogenic; Vascular injury.
Opioid-sparing effects of nefopam during patient-controlled analgesia (PCA) are well demonstrated. We hypothesized that postoperative pain control with an opioid-equivalent dose as a single analgesic agent for PCA would not be inferior to fentanyl in laparoscopic gynecologic surgery. In total, 135 patients were randomly assigned the N (nefopam 200 mg), NF (fentanyl 500 mcg + 100 and F 1000 mcg) groups (n = 45 per group). The primary outcome was numerical rating scale (NRS) score at rest 6 h...
Diaphragmatic eventration is a rare anomaly. When patients with this condition undergo general anesthesia, anesthetic management should be performed particular care owing to the risk of diaphragmatic rupture. Such rupture can perioperatively diagnosed using multiple tools including lung ultrasonography. This case report describes male infant osteochondroma in distal ulna, presenting on right side.
Background: Pediatric patients awakening from general anesthesia may experience emergence delirium (ED), often due to inadequate pain control. Nerve block completely inhibits innervation of the surgical site and is superior systemic analgesics. This study assessed whether control through nerve relieves ED after anesthesia. Methods: Fifty aged 2-7 years with humerus condyle fractures were randomly assigned receive ultrasound guided supraclavicular brachial plexus (BPB group) or intravenous...
Abstract Background Intravenous anesthesia has been reported to have a favorable effect on the prognosis of cancer patients. This study was performed analyze data regarding relation between anesthetics and patients in our hospital. Methods The medical records who underwent surgical resection for gastric, lung, liver, colon, breast January 2006 December 2009 were reviewed. Depending type anesthetic, it divided into total intravenous (TIVA) or volatile inhaled (VIA) group. 5-year overall...
Human milk glycans play an important role in protecting infants from bacterial infections by providing antimicrobial molecules and promoting development of beneficial microbiota. We have shown that hyaluronan human (milk HA), a glycan polymer, induces the expression beta defensin 2 (HBD2), peptide vitro mouse orthologue vivo, through Toll‐like receptor 4 (TLR4) CD44 dependent manner . Importantly, HA reduces Salmonella infection intestinal epithelial cells hypothesized addition to HBD2,...
Given the possibility of profound bradycardia, asystole, or even death when evoked, it is important to be aware trigeminocardiac reflex during surgical stimulation mandibular divisions trigeminal nerve, in particular TMJ.
Crowned dens syndrome (CDS) is a cause of neck pain characterized by calcium deposition in the periodontoid tissues. Clinical features are acute onset and headache with fever. Computed tomographic imaging necessary for diagnosis. The prognosis CDS excellent. Symptoms disappear within several weeks calcifications may be absorbed. We report case severe pain, facial pharyngeal provoked swallowing. Keywords: Calcification; Facial pain; Fever; Headache; Neck Odontoid process
Background: The trigeminocardiac reflex (TCR), which occurs after stimulation of the territory trigeminal nerve, is very rarely reported to be caused by mandibular branch. We report a case TCR in open reduction for temporomandibular joint (TMJ) dislocation. Case: A 74-year-old female presented TMJ During under general anesthesia, severe bradycardia (15 beats/min) occurred. Immediately 0.5 mg atropine was administered intravenously, and surgical manipulation stopped. After 30 seconds, heart...
Abstract Background: Intravenous anesthesia has been reported to have a favorable effect on the prognosis of cancer patients. This study was performed analyze data regarding relation between anesthetics and patients in our hospital. Methods: The medical records who underwent surgical resection for gastric, lung, liver, colon, breast January 2006 December 2009 were reviewed. Depending type anesthetic, it divided into total intravenous (TIVA) or volatile inhaled (VIA) group. 5-year overall...