A5011507351- Thyroid Cancer Diagnosis and Treatment
- Effects and risks of endocrine disrupting chemicals
- Thyroid and Parathyroid Surgery
- Animal Genetics and Reproduction
- Reproductive Biology and Fertility
- Pancreatic function and diabetes
- Head and Neck Anomalies
- Thyroid Disorders and Treatments
- Nutrition and Health in Aging
- Radiomics and Machine Learning in Medical Imaging
- Food Quality and Safety Studies
- Adrenal and Paraganglionic Tumors
- Heavy Metal Exposure and Toxicity
- Pituitary Gland Disorders and Treatments
- Metabolism, Diabetes, and Cancer
- Bone health and osteoporosis research
- Meat and Animal Product Quality
- Diabetes and associated disorders
- Toxic Organic Pollutants Impact
- Neuroendocrine Tumor Research Advances
- Nutrition, Health and Food Behavior
- Growth Hormone and Insulin-like Growth Factors
- Liver Disease Diagnosis and Treatment
- Vitamin D Research Studies
- Cancer, Lipids, and Metabolism
Seoul National University Bundang Hospital
2012-2025
Seoul National University Hospital
2013-2025
Seoul National University
2015-2024
Asan Medical Center
2012-2024
Ulsan College
2012-2024
University of Ulsan
2012-2024
Hanyang University
2024
New Generation University College
2011-2024
Changwon National University
2023
Vanderbilt University
2023
Bisphenol A (BPA) has been reported to possess hepatic toxicity.We investigated the hypothesis that BPA, below no observed adverse effect level (NOAEL), can induce damage and mitochondrial dysfunction by increasing oxidative stress in liver.Two doses of 0.05 1.2 mg/kg body weight/day, were administered intraperitoneally for 5 days mice.Both treatments impaired structure mitochondria, although oxygen consumption rate expression respiratory complex decreased only at higher dose.The levels...
Phthalates and bisphenol A (BPA) have been suspected as risk factors for obesity diabetes mellitus (DM) among humans. However, associations between phthalates environmental phenols are often inconsistent across different populations. In this study, we recruited the adult population (n = 3782) of Korean National Environmental Health Survey (KoNEHS) 2015-2017 (Cycle 3) assessed urinary biomarkers phthalate, BPA, paraben exposure with DM. potential collider issue use creatinine (Cr) or specific...
Environmental pollutants have been known to increase the risks of not only respiratory and cardiovascular disease but also metabolic diseases such as obesity diabetes mellitus (DM). Polycyclic aromatic hydrocarbons (PAHs) volatile organic compounds (VOCs) benzene toluene are major constituents environmental pollution. In present study, we employed population Korean National Health Survey (KoNEHS) Cycle 3 conducted between 2015 2017, assessed associations urinary biomarkers for PAHs VOCs...
Background: Active surveillance (AS) is an alternative to thyroidectomy for the management of low-risk papillary thyroid microcarcinoma (PTMC). However, prospective AS data collected from diverse populations are needed. Methods: This multicenter cohort study enrolled patients three referral hospitals in Korea. The participants were self-assigned into two groups, or immediate surgery. All underwent neck ultrasound every 6–12 months monitor disease progression. Progression under was evaluated...
Background: In this ongoing multicenter prospective cohort study on active surveillance (AS) in low-risk papillary thyroid microcarcinoma (PTMC), we aimed to compare the quality of life (QoL) participants based their choice treatment, that is, AS or immediate surgery (OP). Methods: QoL 203 who chose and 192 underwent OP was evaluated using a thyroid-specific questionnaire at diagnosis during follow-up (median 8 months). Results: The mean ages groups were 47.3 ± 11.7 45.6 10.5 years (p =...
Abstract Although various chemokines have pro-tumorigenic actions in cancers, the effects of CXCL16 remain controversial. The aim this study was to investigate molecular characteristics CXCL16-expressing papillary thyroid cancers (PTCs). expressions were significantly higher PTCs than benign or normal tissues. In TCGA dataset for PTCs, a expression associated with M2 macrophage- and angiogenesis-related genes poor prognostic factors including TNM staging BRAF V600E mutation. 3-gene panel ,...
Background: Among follicular variant papillary thyroid carcinomas (FVPTCs), the noninvasive encapsulated subtype has an excellent prognosis. For this reason, reclassification of FVPTC (EFVPTC) as a new entity called "noninvasive neoplasm with papillary-like nuclear features" (NIFTP) been proposed, but controversy remains. To characterize EFVPTC in Asian population, clinicopathologic features each were compared Korean population. Methods: patients (n = 142) who underwent thyroidectomy between...
The association between nonalcoholic fatty liver disease (NAFLD) and sarcopenia has been suggested. We investigated the NAFLD independent of visceral adiposity searched for clinical characteristics that affect this association.We performed a retrospective study including 5,989 subjects (mean age, 53.2 years; men, 57.3%) who underwent bioelectrical impedance analysis (BIA) abdominal ultrasonography in 2012. appendicular skeletal muscle mass (ASM) was assessed by BIA method. Sarcopenia defined...
The ongoing Multicenter Prospective Cohort Study of Active Surveillance on Papillary Thyroid Microcarcinoma (MAeSTro) aims to observe the natural course papillary thyroid microcarcinoma (PTMC), develop a protocol for active surveillance (AS), and compare long-term prognosis, quality life, medical costs between AS immediate surgery groups.This multicenter prospective cohort study PTMC started in June 2016. inclusion criteria were suspicious malignancy or based fine needle aspiration core...
Exposure to consumer chemicals such as phthalates and phenolic compounds has been associated with thyroid hormone disruption in humans. However, information related factors that may influence associations, e.g., transport activation of the hormones, autoimmunity status, is limited. In present study, we employed a subpopulation adults (n = 1,254) who participated Korean National Environmental Health Survey (KoNEHS) 2015-2017, urinary concentrations major phthalate metabolites, bisphenol A...
Metabolic (dysfunction)-associated fatty liver disease (MAFLD) emphasizes the metabolic dysfunction in nonalcoholic (NAFLD). Although relationship between low muscle mass and NAFLD has been suggested, effect of MAFLD on is yet to be investigated. In this study, we examined an asymptomatic Korean population.Examinees who underwent FibroScan® bioelectrical impedance analyses same day during period June 2017 December 2019 were included. Hepatic steatosis was diagnosed using controlled...