A5072143509- Liver Disease Diagnosis and Treatment
- Liver Disease and Transplantation
- Diet, Metabolism, and Disease
- Helicobacter pylori-related gastroenterology studies
- Galectins and Cancer Biology
- Eosinophilic Esophagitis
- Liver Diseases and Immunity
- Lipid metabolism and disorders
- Cardiovascular Disease and Adiposity
- Cardiovascular Function and Risk Factors
- Nutrition and Health in Aging
- Folate and B Vitamins Research
- Alcohol Consumption and Health Effects
- Gastroesophageal reflux and treatments
- Thyroid Disorders and Treatments
- Pancreatitis Pathology and Treatment
- Endometriosis Research and Treatment
- Veterinary medicine and infectious diseases
- Pregnancy and preeclampsia studies
- Microscopic Colitis
- Cannabis and Cannabinoid Research
- Viral Infections and Immunology Research
- Health and Well-being Studies
- Cancer Risks and Factors
- Frailty in Older Adults
Seoul National University Hospital
2014-2024
Ewha Womans University
1996-1997
Abstract Background The aim of this study was to evaluate the time trend seropositivity Helicobacter pylori ( H . ) over period 13 years in an asymptomatic Korean population, and investigate associated risk factors. Methods This cross-sectional nationwide multicentre surveyed anti- IgG antibodies 19,272 health check-up subjects (aged [greater than equal to]16 years) 2011. Risk factors for infection were investigated using logistic regression. Seropositivity without eradication compared...
Abstract Background: Helicobacter pylori ‐associated gastrointestinal diseases have been widely recognized. The aims of this study were to investigate the interval change seropositivity H. between 1998 and 2005 in Korean adult population find factors related infection. Methods: Between January December 2005, a total 15,916 health check‐up subjects (aged ≥ 16 years) from all parts South Korea responded questionnaire, prevalence was investigated by measuring anti‐ H IgG antibodies....
Summary Background Non‐alcoholic fatty liver disease ( NAFLD ) is known to be associated with polycystic ovary syndrome PCOS ). However, most studies investigated the prevalence of in obese patients. Aim To compare non‐obese women or without , and assess an independent association between a Asian cohort. Methods This was case–control study using prospective After subjects other potential causes chronic were excluded, 275 892 controls enrolled. determined by hepatic ultrasonography. Main...
The aims of this study were to demonstrate the trends in seropositivity and eradication therapy rate for Helicobacter pylori (H. pylori) over an 18-year period asymptomatic Korean population explore factors associated with H. its therapy. In total, 23,770 subjects (aged 17–97 years) from a health examination center participated cross-sectional January 2016 June 2017. Questionnaires that included questions about participants’ history collected, anti-H. IgG antibodies measured. Among eligible...
Abstract Background & Aims Testosterone plays a role in predisposing individuals to cardiovascular and metabolic diseases, but its effects differ between men women. We investigated the association serum total testosterone non‐alcoholic fatty liver disease adults US . Methods A cross‐sectional analysis of data from participants 2011‐2012 National Health Nutrition Examination Survey was performed. Subjects with significant alcohol consumption those viral hepatitis were excluded. used...
The development of nonalcoholic fatty liver disease (NAFLD) is associated with multiple genetic and environmental factors.We performed a genome-wide association study to identify the factors related NAFLD in Korean population-based sample 1,593 subjects 2,816 controls. We replicated data another that included 744 patients 1,137 investigated single-nucleotide polymorphisms (SNPs) were NAFLD.After adjusting for age, sex body mass index, rs738409, rs12483959 rs2281135, located PNPLA3 gene,...
The association between nonalcoholic fatty liver disease (NAFLD) and sarcopenia has been suggested. We investigated the NAFLD independent of visceral adiposity searched for clinical characteristics that affect this association.We performed a retrospective study including 5,989 subjects (mean age, 53.2 years; men, 57.3%) who underwent bioelectrical impedance analysis (BIA) abdominal ultrasonography in 2012. appendicular skeletal muscle mass (ASM) was assessed by BIA method. Sarcopenia defined...
Metabolic (dysfunction)-associated fatty liver disease (MAFLD) emphasizes the metabolic dysfunction in nonalcoholic (NAFLD). Although relationship between low muscle mass and NAFLD has been suggested, effect of MAFLD on is yet to be investigated. In this study, we examined an asymptomatic Korean population.Examinees who underwent FibroScan® bioelectrical impedance analyses same day during period June 2017 December 2019 were included. Hepatic steatosis was diagnosed using controlled...
BackgroundStudies have reported a significant association between pregravid weight gain and the subsequent development of gestational diabetes mellitus (GDM) in various populations. The current study aims to investigate this relationship using data from Korean National Health Insurance Service database. MethodsWe conducted retrospective nationwide population-based cohort study, involving 159,798 women who gave birth 2015 2017 had undergone two national health screening examinations: 1 year...
This study aimed to evaluate the efficacy of a new polyclonal enzyme immunoassay for detection Helicobacter pylori (H. pylori) antigen in stool by determination optimal cut-off value screening population.A consecutive 515 patients undergoing routine health check-up were prospectively enrolled. H. infection was defined if at least two four tests (histology, rapid urease test, (13)C-urea breath and serology) positive. A test (EZ-STEP performed pylori. The determined receiver-operator...
Helicobacter pylori causes numerous extragastric manifestations, including coronary heart disease. The artery calcification (CAC) score, measured using computed tomography (CT) has been used as a screening test for atherosclerosis. This study investigated the association between H. seropositivity and CAC scores in population.Patients who underwent health checkup October 2003 July 2007 did not have history of ischemic disease were enrolled study. Subjects screened with multidetector CT scan...
Su Jin Chung, Seon Hee Lim, Jeongmin Choi, Donghee Kim, Young Sun Min Jeong Park, Yoon Yim, Joo Sung Sang-Heon Cho, Hyun Chae Jung and In Song. J Neurogastroenterol Motil 2011;17:267-73. https://doi.org/10.5056/jnm.2011.17.3.267
Background: An association between sarcopenic obesity and cardiovascular disease has been suggested. We investigated the relationship sarcopenia coronary atherosclerosis, taking into account presence or absence of in a health check-up population. Methods: Data were reviewed for subjects who underwent bioelectrical impedance analysis (BIA) calcium scoring (CAC) computed tomography January 2017 December 2018. Appendicular skeletal muscle mass (ASM) was assessed using BIA. Sarcopenia defined as...
Background & aims The impact of marijuana on nonalcoholic fatty liver disease (NAFLD) is largely unknown. We studied the association between and NAFLD utilizing cross-sectional data from National Health Nutrition Examination Survey (NHANES) 2005–2014 NHANES III (1988–1994). Methods Suspected was diagnosed if serum alanine aminotransferase (ALT) > 30 IU/L for men 19 women in absence other diseases (NHANES 2005–2014). In cohort, defined based ultrasonography. Results Of 14,080 2005–2014) 8,286...
Gastroesophageal reflux is a commonly encountered condition, but detailed data on symptoms in Asian countries are lacking.To evaluate the prevalence and to document clinical spectrum of endoscopic esophagitis (RE).A total 25,536 subjects underwent an upper gastrointestinal examination as part health check, completed gastroesophageal questionnaire. Endoscopic findings classified according Los Angeles (LA) classification from questionnaire were analyzed.On basis findings, 2019 (7.91%) found...
Chronic elevations in alanine aminotransferase (ALT) levels are associated with body composition. The aim of this study was to evaluate the relationship between elevated liver enzyme and visceral tissue area subjects without nonalcoholic fatty disease (NAFLD). An observational cohort conducted undergoing general health examinations. To subcutaneous abdominal adipose area, a computed tomography scan performed. NAFLD diagnosed if person demonstrated on ultrasonography history significant...
In patients with diabetes, studies investigating the association between nonalcoholic fatty liver disease (NAFLD) and coronary artery calcium score (CACS) have shown conflicting results. The aim of this study was to evaluate NAFLD CACS in diabetic patients.This is cohort performed Seoul National University Hospital Gangnam Healthcare Center. defined as cases typical ultrasonographic findings without excessive alcohol consumption, medications causing hepatic steatosis or other chronic...
Background Non-alcoholic fatty liver disease (NAFLD) and Helicobacter pylori ( Hp ) infection have a close association with an increased risk of cardiovascular disease. Metabolic dysfunction-associated (MAFLD) is characterized by metabolic dysfunction in NAFLD. We investigated the synergistic effects NAFLD/MAFLD on arterial stiffness asymptomatic population. Methods included individuals who underwent abdominal ultrasonography, anti- IgG antibody evaluations cardio-ankle vascular index (CAVI)...
An epidemiologic shift of hepatitis A virus (HAV) seroprevalence is expected due to an improvement in socioeconomic status young adults Korea. We investigated the age-specific and factors associated with HAV seropositivity young, healthy Korean adults.Between March 2009 February 2010, a total 5,051 persons from 20 49 years age presenting for health check-up were included responded questionaire. The was by measuring immunoglobulin G (IgG) anti-HAV. 984 pairs cases age- sex-matched controls...
Abstract Background & Aims Evaluation of the controlled attenuation parameter ( CAP ) is a promising noninvasive method for assessing hepatic steatosis. Despite increasing reliability steatosis in subjects with chronic liver disease, few studies have evaluated asymptomatic without overt disease. Therefore, we aimed to evaluate usefulness health check‐up population. Methods We enrolled who underwent abdominal ultrasonography US ), FibroScan (Echosens, France) and blood sampling during...