- Bariatric Surgery and Outcomes
- Gastric Cancer Management and Outcomes
- Helicobacter pylori-related gastroenterology studies
- Tuberculosis Research and Epidemiology
- Health and Wellbeing Research
- Obesity and Health Practices
- Health Systems, Economic Evaluations, Quality of Life
- Gastroesophageal reflux and treatments
- Eosinophilic Esophagitis
- Obesity, Physical Activity, Diet
- Schizophrenia research and treatment
- Suicide and Self-Harm Studies
- Nutrition and Health in Aging
- Nutrition, Health and Food Behavior
- Pharmacovigilance and Adverse Drug Reactions
- Rheumatoid Arthritis Research and Therapies
- Pharmaceutical Practices and Patient Outcomes
- Nutritional Studies and Diet
- Health disparities and outcomes
- Bone health and osteoporosis research
- Metastasis and carcinoma case studies
- Esophageal and GI Pathology
- Attention Deficit Hyperactivity Disorder
- Blood Pressure and Hypertension Studies
- Diet and metabolism studies
Kyungpook National University
2016-2025
Drug Discovery Laboratory (Norway)
2021
National Evidenc- based healthcare Collaborating Agency
2012-2019
Seoul National University Bundang Hospital
2017
Yeouido St. Mary's Hospital
2017
Kyungnam University
2015-2016
Hankuk University of Foreign Studies
2015
University of Georgia
2012
Rutgers, The State University of New Jersey
2009-2011
Seoul National University Hospital
2009
Suicide rates have recently been decreasing on average among OECD countries, but increasing trends detected in South Korea, particularly since the 1997 economic crisis. There no detailed analyses about changes of suicide over time periods Korea. We examined both absolute and proportional period development, crisis, recovery (1986 - 2005) as well birth cohorts from 1924 to 1978. used data total mortality 1986 2005 published online by Korean National Statistical Office (NSO) extracted for...
Abstract Background The aim of this study was to evaluate the time trend seropositivity Helicobacter pylori ( H . ) over period 13 years in an asymptomatic Korean population, and investigate associated risk factors. Methods This cross-sectional nationwide multicentre surveyed anti- IgG antibodies 19,272 health check-up subjects (aged [greater than equal to]16 years) 2011. Risk factors for infection were investigated using logistic regression. Seropositivity without eradication compared...
A regular menstrual cycle is an important indicator of a healthy reproductive system. Previous studies reported obesity, stress, and smoking as the factors that are associated with irregular menstruation early menopause. However, integrative effects these modifiable risk have not been fully understood. This study aimed to investigate irregularity premature menopause, well their individual combined among adult women in Korea. selected aged 19 years above who had included 2007–2014 Korean...
Abstract Background Kidney transplant recipients (KTRs) are at high risk for cardiovascular disease due to the long‐term use of immunosuppressive therapy. This study aims evaluate impact sirolimus on outcomes in Korean KTRs. Methods From a cohort 7180 eligible KTRs identified from 2010 2021, 387 who received were included. To control confounding variables, propensity score matching was applied, and landmark method used address immortal time bias. The primary outcome major adverse events...
The aims of this study were to demonstrate the trends in seropositivity and eradication therapy rate for Helicobacter pylori (H. pylori) over an 18-year period asymptomatic Korean population explore factors associated with H. its therapy. In total, 23,770 subjects (aged 17–97 years) from a health examination center participated cross-sectional January 2016 June 2017. Questionnaires that included questions about participants’ history collected, anti-H. IgG antibodies measured. Among eligible...
Background: Adherence to tuberculosis (TB) drugs is one of the key aspects global TB control, yet there a lack epidemiological evidence on factors influencing adherence drugs. Thus, this study aimed explore and associated with among patients in South Korea. Methods: We conducted cohort using sampled national healthcare database from 2017 2018. Our population included incident initiating quadruple or triple regimen who were available for follow-up 180-days. was evaluated proportion days...
This study examines (a) the heterogeneity in individual multidimensional health trajectories and (b) socioeconomic stratification of during late older years. used prospective data from 1,945 adults, 75 to 85 years old, collected over an 8-year period Health Retirement Study. To examine inconsistent findings research literature, a latent trajectory class analysis was performed. Multidimensional overall showed three heterogeneous classes (maintaining, persistently high, deteriorating),...
Objectives This study aimed to evaluate the risk of tuberculosis associated with use Janus kinase (JAK) inhibitors or biological disease-modifying antirheumatic drugs (bDMARDs) in patients diagnosed rheumatoid arthritis (RA) South Korea. Methods In this nationwide matched-cohort study, we retrospectively identified adult new-onset RA from National Health Insurance Service database who were prescribed bDMARDs JAK and recently underwent latent infection (LTBI) screening during 2012‒2021,...
The objective of this study is to investigate gender differences obesity on major chronic diseases in elderly Korean males and females. This applied a cross sectional design using the 2005 National Health Nutrition Examination Survey (KNHNES). We selected 508 830 females who were 60 or more years old. Obesity was defined Body Mass Index (BMI) (≥ 25) Waist Circumference (WC) 90 for men ≥ 85 women). surveylogistic regression determine relation effect eleven diseases. Using WC, 46.2% obese...
The aim of this study was to analyze the potential adverse events (AEs) caused by Janus kinase (JAK) inhibitors, including tofacitinib, baricitinib, and upadacitinib, used treat rheumatoid arthritis using spontaneous AE reports from FDA (FAERS) interpreting them in correlation with those Korea (KAERS) an online patient review (WebMD). Potential AEs were identified based on a disproportionality analysis proportional reporting ratio (PRR), odds (ROR), information component (IC). A total 23,720...
We examined changes in the prevalence of diabetes, obesity, and overweight 412,881 Korean men birth cohorts from 1933 to 1972 over 8 years 1992 2000 separately analyzed effects age, time period, cohort.The study included male employees government organizations schools who were between 20 59 age 1992. Diabetes was diagnosed on basis self-reports or fasting blood glucose levels (>or=126 mg/ml, 7.0 mmol/l). The age-period-cohort model used estimate cohort.In 1972, age-specific aged 28-59...
In Korea, the results of bariatric surgery have not been compared with those nonsurgical treatment. The purpose this study was to evaluate effectiveness and safety vs. conventional treatment in severely obese Koreans.In retrospective cohort study, we reviewed medical charts 261 consecutive subjects who underwent 224 were treated weight control medication lifestyle modification therapy between January 2008 February 2011. Measures clinical effectiveness, including change (%) comorbid diseases,...
Background/Aims: This study was conducted to evaluate whether medical costs can be reduced using endoscopic submucosal dissection (ESD) instead of conventional surgeries in patients with early gastric cancer (EGC).Methods: Patients who underwent open gastrectomy (OG), laparoscopyassisted (LAG), and ESD for EGC were recruited from three institutions 2009.For macro-costing, the each patient derived expenses incurred during patient's hospital stay 1-year follow-up.The overall micro-costing...
Endoscopic submucosal dissection (ESD) is an effective treatment for early gastric cancer (EGC) that has demonstrated a minimal risk of lymph node metastasis in retrospective studies. We sought to prospectively evaluate the short-term outcomes ESD EGCs.A prospective multicenter cohort study neoplasms 3 cm or less diameter at endoscopic size evaluation was performed 12 Korean grouprelated university hospitals and National Cancer Center. Resected specimens were evaluated by central pathologic...
Background The association between body mass index (BMI) in late-life and dementia risk remains unclear. We investigated the BMI changes over a 2-year period an elderly Korean population. Methods examined 67 219 participants aged 60–79 years who underwent measurement 2002/2003 2004/2005 as part of National Health Insurance Service-Health Screening Cohort. Baseline characteristics including BMI, socioeconomic status cardiometabolic factors were measured at baseline (2002/2003). difference...
The authors investigated the rupture rate among patients with untreated unruptured intracranial aneurysms (UIAs) in South Korea during 2006-2009.A longitudinal study using national representative health-claim data, including all hospital records for every Korean citizen, was used. Patients a UIA who were 18-80 years old 2006 identified I67.1 ICD-10 code. To select eligible patients, historical period of 1 year prior to first diagnosis utilized. previous diagnosis, subarachnoid hemorrhage...
The purpose of this study was to examine the association between bisphosphonate exposure and osteonecrosis jaw (ONJ) in Korean patients with osteoporosis. A nested case-control performed using claims database during 2002 2010 provided by National Health Insurance Service. We identified a cohort individuals diagnosis osteoporosis 2010. Cases controls were 2004 2010, date potential cases ONJ defined as index date. Bisphosphonate evaluated 2 y prior tested performing conditional logistic...
Recent studies have suggested that Helicobacter pylori could prevent allergic disease, particularly in children. However, whether this is true adults controversial. The aim of study was to investigate there negative association between H. infection and asthma among an area with a high prevalence pylori. This cross-sectional using 2011 health surveillance data. Blood samples were taken from all participants measure serum IgG status. Information on demographics, socioeconomic status, medical...
This study was conducted to analyze and compare the exposure individually prescribed drugs prevalence of polypharmacy according age group concomitant disease in South Korea.The use evaluated average numbers prescription used daily during a year or month, using Korean Health Insurance Claims Database, which is representative over 90% citizens, 2010 2011. The also analyzed diseases age. Polypharmacy defined as 5 more specific observation period, proportions users were calculated comorbidity...
Background/objectives Weight perception, especially misperception, might affect health-related quality of life (HRQoL); however, related research is scarce and results remain equivocal. We examined the association between HRQoL weight misperception by comparing obesity level as measured body mass index (BMI) perception in Korean adults. Methods Study subjects were 43 883 adults aged 19 years or older from cycles IV (2007–2009), V (2010–2012) VI (2013–2014) National Health Nutrition...