Ju Yup Lee

ORCID: 0000-0003-0021-5354
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About
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Research Areas
  • Helicobacter pylori-related gastroenterology studies
  • Gastroesophageal reflux and treatments
  • Gastric Cancer Management and Outcomes
  • Eosinophilic Esophagitis
  • Gastrointestinal motility and disorders
  • Gastrointestinal Tumor Research and Treatment
  • Gastrointestinal disorders and treatments
  • Galectins and Cancer Biology
  • Veterinary medicine and infectious diseases
  • Esophageal and GI Pathology
  • Dysphagia Assessment and Management
  • Diphtheria, Corynebacterium, and Tetanus
  • Clinical Nutrition and Gastroenterology
  • Metastasis and carcinoma case studies
  • Gastrointestinal Bleeding Diagnosis and Treatment
  • Colorectal Cancer Screening and Detection
  • Esophageal Cancer Research and Treatment
  • Colorectal Cancer Surgical Treatments
  • Consumer Behavior in Brand Consumption and Identification
  • Microbial Metabolites in Food Biotechnology
  • Pathogenesis and Treatment of Hiccups
  • Digital Marketing and Social Media
  • Child Nutrition and Feeding Issues
  • Congenital gastrointestinal and neural anomalies
  • Dermatology and Skin Diseases

Keimyung University
2016-2025

Keimyung University Dongsan Medical Center
2015-2023

Weatherford College
2019-2023

Seoul National University Bundang Hospital
2013-2022

Youngstown State University
2022

Korea University
2021

Jeonbuk National University
2021

Samsung Medical Center
2021

Chungnam National University
2021

NIHR Clinical Research Network
2019

The aims of this study were to demonstrate the trends in seropositivity and eradication therapy rate for Helicobacter pylori (H. pylori) over an 18-year period asymptomatic Korean population explore factors associated with H. its therapy. In total, 23,770 subjects (aged 17–97 years) from a health examination center participated cross-sectional January 2016 June 2017. Questionnaires that included questions about participants’ history collected, anti-H. IgG antibodies measured. Among eligible...

10.1371/journal.pone.0204762 article EN cc-by PLoS ONE 2018-10-17

This study used image congruity theory to understand customer loyalty in name-brand coffee shops Korea. The authors developed and tested a structural model that links (self-congruity functional congruity) brand components (cognitive, affective, conative loyalty). elaboration likelihood was the information processing underlying model. results showed self-congruity significantly influences both cognitive affective central route of persuasion. Functional peripheral communication. suggests...

10.1177/1096348012471377 article EN Journal of Hospitality & Tourism Research 2013-01-02

Atrophic gastritis is a precancerous condition, which can be diagnosed by several methods. However, there no consensus for the standard method. The aim of this study was to evaluate correlations among endoscopic, histologic, and serologic findings diagnosis atrophic gastritis.From March 2003 August 2013, total 2,558 subjects were enrolled. Endoscopic graded Kimura-Takemoto classification histological assessed updated Sydney system. Serological assessment based on serum pepsinogen test.The...

10.15430/jcp.2014.19.1.47 article EN Journal of Cancer Prevention 2014-03-30

Functional dyspepsia (FD) is one of the most common gastrointestinal disorders, and FD imposes social economic burden worldwide. The aim this study to identify prevalence risk factors in health check-up population tertiary centers Korea.A nationwide multicenter prospective was performed at 9 healthcare Korea between September 2016 June 2017. A total 2525 subjects were investigated based on endoscopic findings questionnaires with Rome III criteria, Helicobacter pylori serology (IgG).A 1714...

10.5056/jnm18068 article EN Journal of Neurogastroenterology and Motility 2018-06-25

Antimicrobial resistance of Helicobacter pylori (H pylori) affects the efficacy eradication therapy. The aim this study was to estimate prevalence primary and secondary H isolates antibiotics in Korea.The present performed from 2003 2018. Primary evaluated 591 patients without any history 149 whom cultured after failure eradication. A minimal inhibitory concentration test for amoxicillin, clarithromycin, metronidazole, tetracycline, levofloxacin, rifabutin using agar dilution method.An...

10.1111/hel.12660 article EN Helicobacter 2019-09-11

Tegoprazan is a novel potassium-competitive acid blocker used to treat acid-related disorders.To compare tegoprazan 25 mg with lansoprazole 15 as maintenance therapy in healed erosive oesophagitis (EE) METHODS: In this phase 3, double-blind, multi-centre study, patients endoscopically confirmed EE were randomised 1:1 receive or once daily for up 24 weeks. The primary efficacy endpoint was the endoscopic remission rate after secondary 12 Safety endpoints included adverse events, clinical...

10.1111/apt.17255 article EN cc-by-nc-nd Alimentary Pharmacology & Therapeutics 2022-10-31

Achalasia is classified into 3 types according to the Chicago classification. The aim of this study was investigate characteristics and treatment outcomes achalasia subtypes in Korean patients.Fifty-five patients diagnosed with based on conventional or high-resolution esophageal manometry were consecutively enrolled. Their clinical characteristics, manometric, endoscopic esophagographic findings responses analyzed among achalasia.Of 55 patients, 21 (38.2%) had type I, 28 (50.9%) II 6 (10.9%)...

10.5056/jnm.2013.19.4.485 article EN cc-by-nc Journal of Neurogastroenterology and Motility 2013-10-28

Beom Jin Kim, Hyuk Lee, Yong Chan Seong Woo Jeon, Gwang Ha Hyun-Soo Jae Kyu Sung, Dong Ho Heung Up Moo In Park, Il Ju Choi, Soon Man Yoon, Sang Wook Baik, Yup Gyun Jayoun Joongyup Gyu and J. Korean College of Helicobacter Upper Gastrointestinal Research. Gut Liver 2019;13:531-40. https://doi.org/10.5009/gnl19136

10.5009/gnl19136 article EN cc-by-nc Gut and Liver 2019-07-22

Prokinetic agents and neuromodulators are among the treatment options for functional dyspepsia (FD), but their comparative efficacy is unclear. We aimed to compare of mosapride controlled-release (CR) nortriptyline in patients with FD after 4 weeks treatment.

10.5056/jnm23147 article EN Journal of Neurogastroenterology and Motility 2024-01-04

Abstract Background The operative link on gastric atrophy (OLGA) and intestinal metaplasia (OLGIM) stages have been suggested for risk estimation of cancer (GC). However, usefulness OLGA/OLGIM systems in diffuse type GC was not investigated so far. aims this study were to evaluate the estimating according Lauren's classification investigate interaction among factors. Materials methods evaluated 1398 (765 control 633 patients) who prospectively enrolled Seoul National University Bundang...

10.1111/hel.12542 article EN Helicobacter 2018-10-10

Abstract Background The 13 C‐urea breath test ( C‐ UBT ) is a noninvasive method for diagnosing Helicobacter pylori H. infection. aims of this study were to evaluate the diagnostic validity cutoff value and identify influencing clinical factors responsible aberrant results. Methods UB iTkit; Otsuka Pharmaceutical, value: 2.5‰) results in range 2.0‰ 10.0‰ after eradication therapy compared with endoscopic biopsy antrum body. Factors considered affect adversely analyzed. Results Among patients...

10.1111/hel.12189 article EN Helicobacter 2015-01-29

The colonic response to stress is greater in female rats than male rats. aim of this study was evaluate the effect probiotics repeated water avoidance (rWAS)-induced microinflammation model Wistar a sex-specific manner. three groups (no-stress, WAS, and WAS with probiotics) were exposed r-WAS for 1 h daily 10 days, Lactobacillus farciminis administered by oral gavage days animals group. visceromotor (VMR) colorectal distension (CRD) assessed using barostat noninvasive manometry before after...

10.1371/journal.pone.0188992 article EN cc-by PLoS ONE 2017-12-15

To identify whether first-degree relatives (FDRs) of gastric cancer (GC) patients have increased risk for atrophic gastritis (AG) and intestinal metaplasia (IM) in relation to other factors GC.The study cohort consisted 224 pairs age-sex matched controls FDRs. AG IM the mucosa were scored histologically using updated Sydney classification. Risk having was studied by comparing FDRs controls. Impacts age, H. pylori infection, smoking, dietary socioeconomic on presence studied.In multivariate...

10.15430/jcp.2013.18.2.149 article EN Journal of Cancer Prevention 2013-06-30

Objective. The eradication rate of 10-day sequential therapy for Helicobacter pylori (H. pylori) infection was not satisfactory in Korea, probably due to antibiotic resistance. To compare the treatment efficacy 15-day and conventional 7-day proton pump inhibitor (PPI) triple H. infection. Methods. A total 332 patients with were randomly assigned receive either PPI therapy, or therapy. Eradication rate, drug compliance, adverse events compared among three regimens. Results. rates by...

10.3109/00365521.2014.896409 article EN Scandinavian Journal of Gastroenterology 2014-07-03

Emerging evidence shows that the mechanism of irritable bowel syndrome (IBS) is associated with neurotrophic factors and tight junction proteins (TJPs). It known there are sex differences in pathophysiology IBS. The aim present study to determine expression levels factors, TJPs, cytokines according IBS subtype sex.From 59 (33 IBS-constipation, 21 IBS-diarrhea, 5 IBS-mixed) 36 control patients, colonic mucosa mRNA transient receptor potential vanilloid-1 (TRPV1), nerve growth factor (NGF),...

10.5056/jnm19099 article EN Journal of Neurogastroenterology and Motility 2019-10-18
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