A5041476521- Pharmaceutical Practices and Patient Outcomes
- Pharmacy and Medical Practices
- Medication Adherence and Compliance
- Patient Safety and Medication Errors
- Pain Management and Opioid Use
- Health Systems, Economic Evaluations, Quality of Life
- Opioid Use Disorder Treatment
- Blood Pressure and Hypertension Studies
- Inflammatory mediators and NSAID effects
- Antiplatelet Therapy and Cardiovascular Diseases
- Venous Thromboembolism Diagnosis and Management
- Atrial Fibrillation Management and Outcomes
- Pharmaceutical Economics and Policy
- Emergency and Acute Care Studies
- Intensive Care Unit Cognitive Disorders
- Diabetes Treatment and Management
- Renal Transplantation Outcomes and Treatments
- Electrolyte and hormonal disorders
- Pneumocystis jirovecii pneumonia detection and treatment
- Economic and Financial Impacts of Cancer
- Helicobacter pylori-related gastroenterology studies
- Pharmacological Effects and Toxicity Studies
- Pharmacovigilance and Adverse Drug Reactions
- Coronary Interventions and Diagnostics
- Gastrointestinal motility and disorders
Yeungnam University
2018-2025
Seoul National University
2022-2023
Yeungnam University College
2022
Hanyang University
2014-2016
Seoul National University Hospital
2008
Abstract Background Kidney transplant recipients (KTRs) are at high risk for cardiovascular disease due to the long‐term use of immunosuppressive therapy. This study aims evaluate impact sirolimus on outcomes in Korean KTRs. Methods From a cohort 7180 eligible KTRs identified from 2010 2021, 387 who received were included. To control confounding variables, propensity score matching was applied, and landmark method used address immortal time bias. The primary outcome major adverse events...
Aim To estimate the incidence and characteristics of typical complications associated with immunosuppressant therapy across various types rheumatic disease (RD). Methods We conducted a retrospective analysis using Korean claims data, including patients who were first diagnosed (rheumatoid arthritis, spondyloarthrosis, lupus erythematosus, vasculitis, sclerosis, Sjögren's syndrome, polymyalgia rheumatica) initiated between 2015 2018. focused on several complications, infections, cancer,...
In older adults, depression is associated with several other clinical problems such as cognitive impairment and low quality of life. Several studies have evaluated the relationship between vitamin D in adults; however, results been controversial thus far.This study aimed to investigate effects supplementation on depressive symptom improvement among individuals aged ≥60 years or without a diagnosis symptoms based meta-analysis randomized controlled trials (RCTs).RCTs were identified analyze...
Abstract We aimed to evaluate antiepileptic drug treatment persistence and adherence in paediatric epilepsy patients investigate the association between medication‐taking behaviours clinical outcome. Methods . Medical prescription records of newly treated patients, aged 1–18 years who initiated monotherapy a tertiary teaching hospital, were retrospectively reviewed. The rates overall treatment, non‐persistence, gap >60 days, adherence, as measured by medication possession ratio ≥0.8,...
Few studies have evaluated the association between anticholinergic burden and treatment modification after starting a cholinesterase inhibitor in clinical practice. We aimed to evaluate effect of on anti-dementia modification, delirium mortality. retrospectively analysed older adults (n = 25 825) who started during 2003-2011 from Korean National Health Insurance Service Senior Cohort Database. High was defined as an average daily Anticholinergic Cognitive Burden (ACB) score >3 first 3...
Effects of Initial Therapeutic ClassesWe aimed to assess one-year persistence with antihypertensive therapy (AHT) among newly treated uncomplicated hypertensive patients in Korea and evaluate the effect initial therapeutic classes on persistence.We retrospectively analyzed a random sample 20% (n = 45,787) 2012 from National Health Insurance claims database.This group was classified into six cohorts based AHT class.We then measured treatment persistence, allowing prescription gap 60...
Objectives: Older adults are more likely to experience drug-related problems (DRP), which could lead medication-related emergency department visits (MRED). To properly evaluate MRED, the entire history of drug use should be evaluated in a structured manner. However, limited studies have identified MRED with complete prescription records. We aimed prevalence and risk factors among community-dwelling older patients by linking national claims data electronic medical records using standardized...
Abstract Opioid overdose can be serious adverse effects of opioid analgesics. Thus, several strategies to mitigate risk and reduce the harm have been developed. However, despite a marked increase in analgesic consumption Korea, there no tools predicting Korean population. Using national claims database population, we identified patients who were incidentally prescribed non-injectable (NIOA) at least once from 2017 2018 (N = 1,752,380). Among them, 866 cases occurred, per case, four controls...
The aim of this study was to investigate trends in the prevalence potentially inappropriate opioid prescribing (PIOP) and identify potential risk factors among Korean noncancer patients.We conducted a cross-sectional annual national patient sample data from Health Insurance Review Assessment Service (HIRA-NPS) for period 2012-2018. Noncancer patients who were prescribed non-injectable analgesics (NIOAs) at least once included. proportion with one PIOP terms concurrent use benzodiazepines or...
Background: Residents in long-term care (LTC) facilities (LTCFs) may have multimorbidity and be unable to self-administer medication. Thus, due the risk of potentially inappropriate medications (PIMs), epidemiological studies on PIM use its associated factors should conducted ensure safe medication for residents LTCFs. Objective: We evaluated among LTCF LTCFs Korea using a nationwide database. Methods: This cross-sectional study used National Health Insurance Service Senior Cohort (KNHIS-SC)...
Background Oral anticoagulants (OACs) are essential for the prevention and treatment of thromboembolic disorders, but bleeding, a major complication, can have fatal impact on patient’s treatment. Objectives We aimed to estimate nationwide, real-world incidence rate bleeding in patients taking OACs confirm by indications risk factors. Methods This cross-sectional study identified OAC users from April 1 December 31, both 2019 2020, using HIRA-NPS database. The primary outcome variables were...
The use of proton pump inhibitors (PPI) is recommended to prevent nonsteroidal anti-inflammatory drug (NSAID)-induced gastrointestinal (GI) complications. incidence several adverse effects during the long-term PPI prompts search for other alternatives. Limited studies have evaluated efficacy rebamipide, a widely used mucoprotective drug, as gastroprotective agent (GPA) compared PPI, focusing on elderly chronic NSAID users, nor with GI risk stratification. We aimed determine population who...