A5101438143- Head and Neck Cancer Studies
- Salivary Gland Tumors Diagnosis and Treatment
- Head and Neck Surgical Oncology
- Voice and Speech Disorders
- Tracheal and airway disorders
- Inflammatory mediators and NSAID effects
- Ear and Head Tumors
- Head and Neck Anomalies
- Dysphagia Assessment and Management
- CAR-T cell therapy research
- Tumors and Oncological Cases
- Estrogen and related hormone effects
- Thyroid Cancer Diagnosis and Treatment
- Airway Management and Intubation Techniques
- Virus-based gene therapy research
- RNA Interference and Gene Delivery
- Speech Recognition and Synthesis
- Cancer, Stress, Anesthesia, and Immune Response
- Vascular Malformations and Hemangiomas
- Eicosanoids and Hypertension Pharmacology
- Cleft Lip and Palate Research
- Reconstructive Surgery and Microvascular Techniques
- Cancer-related molecular mechanisms research
- Phonetics and Phonology Research
- Medical Imaging and Pathology Studies
Seoul National University
2010-2024
Seoul National University Hospital
2010-2024
New Generation University College
1998-2013
National University College
2003-2013
Seoul National University Bundang Hospital
2013
Immunité et Cancer
2009
Cancer Research Center
2009
Clinical Research Institute
2003-2007
Daejeon University
2004
Palmetto Hematology Oncology
2004
<h3>Background</h3> Adenoid cystic carcinoma (ACC) is a unique tumor characterized by frequent and delayed distant metastasis (DM) with uncommon regional lymph node metastasis. <h3>Objectives</h3> To evaluate the factors affecting DM of ACC survival after appearance DM. <h3>Design</h3> A retrospective analysis 94 cases from 1979 through 2001. <h3>Setting</h3> Academic tertiary referral center. <h3>Results</h3> Distant occurred in 46 patients developed more frequently tumors solid histologic...
To evaluate the efficacy and safety of radiofrequency ablation (RFA) for localized small recurrent thyroid cancers less than 2 cm by comparing them with those at repeat surgery.This retrospective study was institutional review board-approved, informed consent waived. From December 2008 to 2011, this evaluated 73 patients (17 men 56 women; age, 50.3 years ± 13.6) cancer who had been treated RFA (n = 27) or surgery 46) met following criteria: (a) three fewer recurrences lesions high...
OBJECTIVES This study retrospectively reviews the results of sclerotherapy using several sclerosants for congenital lesions head and neck. METHODS AND PATIENTS Between May 1990 2002, patients with lymphatic malformations were treated by sclerotherapy; 10 bleomycin, 25 OK‐432. OK‐432 was also applied in 9 plunging ranula 1 patient branchial anomaly. Percutaneous ethanolamine oleate used 29 venous malformations, 28 pyriform sinus fistula trichloroacetic acid chemocauterization. RESULTS...
OBJECTIVES: Non-alcoholic fatty liver disease (NAFLD) is known to be related factors that predict the development of coronary heart (CHD), such as dyslipidemia, central obesity, and metabolic syndrome (MS). The aim this study was determine whether individuals with NAFLD have an elevated risk CHD, estimated using Framingham score (FRS). METHODS: A total 21,130 who underwent a voluntary general health examination were recruited. diagnosed among these on basis typical sonographic findings level...
Objectives/Hypothesis Despite the high prevalence of voice disorders, laryngeal disease in general population has not been determined using laryngoscopy. Factors considered associated with have mostly assessed patient data or highly specific populations. We evaluated and factors diseases Korean population. Study Design Cross‐sectional study. Methods analyzed from Korea National Health Nutrition Examination Survey for 19,039 participants between 2008 2011. The prevalence, subjective...
A branchial remnant originating in the pyriform sinus causes a recurrent fistula or abscess neck. In spite of excision, recurrence may result from inadequate removal tract. We attempted chemocauterization internal opening tract with trichloroacetic acid (TCA) on direct endoscopy. This is 6-year review 18 patients fistula. Medical history, barium esophagography, computed tomography scans, operative findings, and treatment results were analyzed. By endoscopy, all found to have sinus,...
Malignancies arising from the sinonasal tract, which includes nose, paranasal sinuses, and nasopharynx, are uncommon. Although adenoid cystic carcinoma (ACC) is second most common cancer occurring in only few studies have been reported. This retrospective review was performed to identify clinical features treatment outcomes of ACC.Thirty-five patients diagnosed treated for ACC tract were included this study. Medical records, radiographs, pathologic slides retrospectively reviewed.In two...
Abstract Background Pyriform sinus fistula is a rare brachial pouch anomaly. However, it difficult and risky to remove the tract completely. Circumferential chemocauterization of internal opening with trichloroacetic acid (TCA) for pyriform simple, reproducible, reliable, causes less morbidity. The aim this study was determine feasibility TCA fistula. Methods This retrospective enrolled 44 patients who were diagnosed underwent chemocauterization. We retrospectively reviewed medical records...
Background/Aims: The role of induction chemotherapy (IC) for eyeball preservation has not been established in head and neck squamous cell carcinoma (HNSCC) the paranasal sinus nasal cavity (PNSNC). Periorbital involvement frequently leads to exenteration with a margin safety. We evaluated treatment outcomes, including survival preservation, patients who received IC HNSCC PNSNC. Methods: reviewed 21 diagnosed PNSNC were treated IC. analyzed response, rate, overall survival. Results: Tumors...
Congenital lymphatic malformations of the head and neck (LMHN) present special challenges to otolaryngologist-head surgeon. Recently, a number sclerotherapy trials have shown promising results. In this study, we our experiences with picibanil (OK-432) for lesion.Retrospectively review.We retrospectively reviewed 21 patients who undergone LMHN.Satisfactory response complete or nearly shrinkage lesions was observed in 15 cases after repeated (average, two times). We did not observe any...
INTRODUCTION Nonsurgical treatments, such as sclerotherapy have been attempted for head and neck lymphagiomas. Of the available sclerosing agents, picibanil has shown satisfactory short‐term treatment results in many studies, but no study presented long‐term results. Accordingly, present study, authors retrospectively reviewed of sclerotherapy. MATERIALS AND METHODS Fifty‐five lymphangioma patients who underwent were enrolled. Data about initial response, recurrence, excision rate collected....
Abstract Objectives/Hypothesis: Although precise localization of obstruction sites in the upper airway during sleep is essential subjects with obstructive apnea syndrome (OSAS), no gold standard diagnostic method has been established. This study aimed to evaluate dynamic collapse inside by using cine magnetic resonance imaging (MRI), also called MRI. Study Design: Cross‐sectional retrospective data. Methods: The changes transverse and anteroposterior diameters retrolingual were studied a...
The increase in thyroid screening the general population may lead to earlier detection of medullary carcinoma (MTC).We aimed evaluate secular trends clinicopathological characteristics and long-term prognosis MTC its prognostic factors.This was a retrospective analysis from 1982 2012.Three hundred thirty-one patients with were included grouped based on year diagnosis (1982-2000, 2001-2005, 2006-2010 2011-2012).These recurrence mortality as well biochemical remission (BCR) serum...
Abstract The overexpression of cyclooxygenase‐2 (COX‐2) and inducible nitric oxide synthase (iNOS) has been previously reported in head neck squamous cell carcinoma (HNSCC), as well many cancers. We hypothesized that endogenous (NO) might increase the expression COX‐2 cancer cells. Therefore, we investigated cross‐talk between NO prostaglandin (PG) pathways HNSCC lines. found iNOS expressions were elevated simultaneously. On adding donor, SNAP, PGE 2 level was increased 2–20 times due to...
Abstract Objectives: To analyze the impact of neoadjuvant chemotherapy (CT) on treatment early‐stage nasopharyngeal carcinoma (NPC) as compared with radiotherapy (RT) alone. Methods: We analyzed retrospectively outcome 60 previously untreated and histologically confirmed NPC patients treated either RT alone or CT followed by (CT/RT) at Seoul National University Hospital between 1986 2004. Neoadjuvant consisted three cycles 5‐fluourouracil cisplatin. was given to nasopharynx neck nodes. The...
Submandibular gland excision is traditionally performed by the transcervical approach. To avoid or reduce visible scarring and nerve injury, diverse innovative surgical trials have been reported. Here we report a patient who had an endoscopic submandibular resection via hairline incision.A 36-year-old woman presented with right tumor that was found on routine check-up. The resected under assistance posterior incision using ultrasonic scalpel.The successful, causing no acute complications,...
Although ultrasound is regarded as the first choice imaging modality for evaluating a pediatric neck mass, computed tomography (CT) necessary urgent surgical conditions such deep infections. Our aim was to evaluate diagnostic effectiveness of and proper patient selection CT method initial evaluation masses in emergency department.We analyzed medical records 105 patients who visited department with mass whose work-up mass. The parameters investigated included patient's age, sex, symptom...
Objectives. The aim of the present study was to evaluate value high-resolution ultrasound (US) and computed tomography (CT) scan for preoperative prediction extrathyroidal extension (ETE). Methods. We analyzed medical records 377 patients with papillary thyroid carcinoma (PTC) US CT calculate sensitivity, specificity, positive negative predictive values characteristics imaging features (such as contact disruption capsule) presence ETE in postoperative pathologic examination. also evaluated...
Abstract Background Distant metastasis of adenoid cystic carcinoma (ACC) is most commonly identified in the lung, but risk factors are still on debate. Methods Risk for lung were evaluated by using Cox proportional hazards model and Kaplan–Meier curves. Results Of 112 patients, 48% had distant metastasis; 94.4% whom metastasis. Univariable analysis revealed sublingual or minor salivary gland, tumor size ≥2.5 cm, perineural invasion as (hazard ratio [HR]: 1.99 [1.02–3.91], 2.57 [1.19–5.58],...
This study analyzed various clinical and histopathologic factors for patients with early stage squamous cell carcinoma (SCC) of the oral tongue to define a high risk group regional recurrence finally find out indication elective neck dissection (END).Retrospective chart review was performed 63 T1-T2N0 SCC who underwent partial glossectomy with/without END. Clinical assessed were age, gender, T stage, tumor differentiation, depth invasion, pathologic nodal status, intrinsic muscle...