The increasing worldwide incidence of extensively drug-resistant tuberculosis (XDR-TB) has emerged as a threat to public health and (TB) control. Treatment outcomes have varied among studies, data on long-term survival are still scarce.To retrospectively assess the burden, clinical characteristics, treatment outcomes, rate patients with XDR-TB in cohort HIV-negative multidrug-resistant (MDR-TB) South Korea.Medical records were reviewed newly diagnosed or retreated for MDR-TB from 2000 2002....

Rationale: Few large-scale studies have investigated multidrug-resistant tuberculosis (MDR-TB) treatment outcomes relative to drug-resistance patterns.Objectives: To assess the impact of additional drug resistances on and long-term survival in a large HIV-negative MDR-TB cohort.Methods: Treatment patients with newly diagnosed or retreated 2000 2002 were retrospectively analyzed based patterns after 5–8 years follow-up.Measurements Main Results: Of 1,407 MDR-TB, 75 (5.3%) had extensively...

Although the positive effects of recombinant fibroblast growth factor-2 (rFGF-2) in chronic obstructive pulmonary disease (COPD) have been implicated previous studies, knowledge its role COPD remains limited. The mechanism FGF2 a mouse model and therapeutic potential rFGF-2 were investigated COPD. protective evaluated cigarette smoke-exposed or elastase-induced animal models. Inflammation was assessed alveolar cells lung tissues from mice. FGF-2 decreased lungs Intranasal use significantly...

Endobronchial Stent Insertion to Manage Hemoptysis caused by Lung CancerHemoptysis in patients with lung cancer is not uncommon and sometimes have dangerous consequences.Hemoptysis has been managed various treatment options other than surgery medicine, such as endobronchial tamponade, transcatheter arterial embolization radiation therapy.However, these methods can be used only temporarily or are suitable for a patient's condition.We present case which uncontrollable hemoptysis central was...

Empyema caused by transdiaphragmatic extension of pyogenic liver abscess is a very rare complication abscess. patients with unclear respiratory symptoms should be evaluated for the presence underlying Effective drainage appropriate antibiotic use an essential part successful treatment.

Most studies on the effects of ambient ozone asthmatics have been based concentration measurements taken by air monitors in downtown areas. Using a passive sampler, we investigated on-site concentrations pulmonary function and symptoms asthmatics. Twenty moderate to severe who had managed for at least 2 months without changes their medication were enrolled from 3 June 18 July 2005. Respiratory, nasal ocular symptoms, peak expiratory flow (PEF), which was measured twice day, use recorded...

Superior vena cava syndrome (SVCS) is usually caused by extrinsic compression or invasion of the superior (SVC) malignant tumors involving mediastinal structures. Although thymomas are well-known causes SVCS, cases SVCS protruding into adjacent vessels draining SVC with thrombosis have been very rarely reported worldwide. We experienced a 39-year-old female patient that developed after direct left brachiocephalic vein (LBCV) and an anterior mass high maximum standardized uptake value on...

Organizing pneumonia (OP) is an inflammatory lung disease characterized pathologically by the presence of buds granulation tissue in distal air spaces. There are numerous causes OP including acute respiratory infections such as viral and bacterial infections. However, Mycobacterium abscessus (M. abscessus) has rarely been reported a causative pathogen OP. Here, we report 67-year-old woman with rapidly progressive pulmonary M. infection who developed failure (ARF). She was treated...

Raoultella planticola, considered to be an environmental organism, is a rare cause of human infections. Although in recent years the frequency R. planticola infections reported literature has increased, few cases pneumonia caused by have been described. Here, we investigate clinical characteristics, management, and outcomes planticola.Consecutive patients with were included. The medical records treated at Dankook University Hospital from January 2011 December 2017 collected.A total 11 adult...

A patient who has achieved resolution of acute hepatitis B and acquired anti-HBs would get protective immunity against virus (HBV). However, reactivation HBV could happen if the was exposed to an immunocompromised state by using immunosuppressive drugs or chemotherapeutic agents. That is because cccDNA reside within hepatocytes after recovery B. Therefore, guidelines for recommend use prophylactic antiviral agents such as entecavir tenofovir in patients with anti-HBc IgG. The without...

ëª©ì  졸피뎀은 불면증의 치료로 ì•ˆì „í•˜ê³ íš¨ê³¼ì ì¸ 약물이다. 하지만 졸피뎀을 복용한 후 섬망과 같은 부작용이 발생했다는 ë³´ê³ ê°€ 있다. 졸피뎀 ìœ ë°œ 섬망의 ë°œìƒë¥ ê³¼ 위험요인에 대해 연구하였다. 방법 2011ë „ 1월부터 5월까지 ìž ì›í•˜ì—¬ 481ëª ì˜ 환자를 대상으로 대하여 í›„í–¥ì ìœ¼ë¡œ 분석하였다. ê²°ê³¼ 가운데 19ëª (4.0%)에서 섬망이 발생하였다. 65세 이상의 ê³ ë ¹(OR = 4.35, 95% CI...

Lymphocytic hypophysitis is a rare inflammatory disorder which caused by autoimmune destruction of the pituitary gland. Almost all reported cases have been in women and disease often associated with pregnancy. We describe here first male case lymphocytic Korea. The patient presented headache, impotence, decreased libido, deteriorated vision. Endocrinologic studies showed panhypopituitarism, MRI imaging revealed homogeneously enhanced mass thickened stalk. Treatment prednisolone thyroid...

Studies on the effects of viral coinfection bacterial pneumonia are still scarce in South Korea. This study investigates frequency and seasonal distribution virus infection its impact prognosis patients with community-acquired (CAP).The medical records CAP definite etiology, such as viruses bacteria, were retrospectively reviewed. Their epidemiologic clinical characteristics, microbiologic test results, severity illness, 30-day mortality analyzed.Among 150 subjects, 68 (45.3%) had alone, 47...

Wernicke's encephalopathy is a neurologic complication of thiamine deficiency, presenting with acute confusion, oculomotor dysfunction, and gait ataxia.While most often associated chronic alcoholism, occasionally occurs in the setting poor nutritional status, such as malabsorption, increased metabolic requirements, or loss water-soluble vitamins.Patients critical illnesses can present excessive catabolic status because activation sympathetic nervous system pituitary-adrenal axis.In addition,...

Chronic necrotizing pulmonary aspergillosis (CNPA) is an unusual form of arising in the setting mildly immune compromised state or altered local defense system. CNPA rarely shows histological findings mimicking bronchocentric granulomatosis (BCG), which characterized by peribronchiolar granulomatous destruction. We describe a case representing with elements BCG. A-64 year-old woman was admitted because atypical pneumonia multi-focal variable sized consolidations and cavitary lesions on...

Everolimus는 ì „ì´ì„± íˆ¬ëª ì„¸í¬í˜• ì‹ ì„¸í¬ì•”ì˜ ì¹˜ë£Œì œë¡œ 쓰인다. 문헌에는 everolimus 사용 후 간질성 íë ´ì´ ë°œìƒí• ìˆ˜ 있는 것으로 되어 있으나, 국내의 ë³´ê³ ëŠ” 없었다. €ìžë“¤ì€ 세포암에서 투여한 발생한 ´ 1예를 경험하였기에 ë¬¸í—Œê³ ì°°ê³¼ 함께 하는 바이다. 중심 단어: Everolimus; ì•½ì œ ìœ ë°œ ´; 장세포암ì¢

Human placenta contains various kinds of nutritional elements essential for embryonic development.Currently, human extracts are widely overused in Korea to improve certain health conditions (postmenopausal syndrome, liver function, and cosmetic purposes) without scientific evidence that they actually work.The use should be restricted, due a lack systematic research on the therapeutic effectiveness adverse results from these treatments.While common effects have been reported fever, rash,...

<b>Background:</b> Rapid diagnosis of pulmonary tuberculosis (PTB) is critical for TB control. High-resolution computed tomography (HRCT) has been used in the PTB. <b>Aims and objectives:</b> We investigated utility HRCT rapid sputum smear polymerase chain reaction (PCR)-negative <b>Methods:</b> reviewed medical records PCR-negative PTB suspects who checked from January 2011 to December 2014 a tertiary hospital South Korea. Final was made based on culture, bronchoscopy, biopsy appropriate...

Unilateral absence of the pulmonary artery (UAPA) is a rare congenital anomaly that occurs in association with other cardiovascular anomalies, such as tetralogy Fallot or ventricular septal defects.On hand, it less commonly found an isolated finding without accompanying diseases.Isolated UAPA cause hemoptysis, and massive hemoptysis has been reported to occur approximately 18∼20% patients during their clinical course.Even if lung resection considered treatment option control life-threatening...

Bronchopulmonary infections caused by trichomonads have been reported principally in patients with pre-existing pulmonary diseases, such as bronchial carcinoma, lung abscess, or bronchiectasis.Pulmonary trichomoniasis is most often Trichomonas tenax, which usually regarded a harmless commensal organism of the human mouth.However, infection may rarely be other trichomonas species, including vaginalis from genitourinary tract and hominis intestines.Because rarity infection, because its close...