A5100744569- Bone Metabolism and Diseases
- Bone health and treatments
- NF-κB Signaling Pathways
- Magnetic and transport properties of perovskites and related materials
- Electronic and Structural Properties of Oxides
- Mesenchymal stem cell research
- Oral microbiology and periodontitis research
- Pluripotent Stem Cells Research
- Microbial Metabolic Engineering and Bioproduction
- Reproductive Biology and Fertility
- Immune Response and Inflammation
- Spine and Intervertebral Disc Pathology
- Ferroelectric and Piezoelectric Materials
- 3D Printing in Biomedical Research
- Multiferroics and related materials
- Magnetic Properties and Synthesis of Ferrites
- Oral and gingival health research
- Tissue Engineering and Regenerative Medicine
- Corneal Surgery and Treatments
- Periodontal Regeneration and Treatments
- Bone and Dental Protein Studies
- Bone Tissue Engineering Materials
- Inflammatory mediators and NSAID effects
- Corneal surgery and disorders
- S100 Proteins and Annexins
Pusan National University
2015-2024
Konyang University
2023
CJ CheilJedang (South Korea)
2011-2023
Inha University
2023
LG Chem (South Korea)
2019-2022
University of Michigan–Ann Arbor
2022
Korea Brain Research Institute
2022
University of Nebraska Medical Center
2018-2021
Kangdong Sacred Heart Hospital
2021
Hallym University
2021
Transparent electronic materials are increasingly in demand for a variety of optoelectronic applications, ranging from passive transparent conductive windows to active thin-film transistors. BaSnO${}_{3}$ is semiconducting oxide with large band gap more than 3.1 eV. Recently, we discovered that doped few percent La exhibits an unusually high electrical mobility...
We discovered that La-doped BaSnO3 with the perovskite structure has an unprecedentedly high mobility at room temperature while retaining its optical transparency. In single crystals, reached 320 cm^2(Vs)^-1 a doping level of 8x10^19 cm^-3, constituting highest value among wide-band-gap semiconductors. epitaxial films, maximum was 70 4.4x10^20 cm^-3. also show resistance (Ba,La)SnO3 changes little even after thermal cycle to 530 Deg. C in air, pointing unusual stability oxygen atoms and...
We have developed RGD-attached gold (Au) half-shell nanoparticles containing methotrexate (MTX) for the treatment of rheumatoid arthritis (RA), where MTX is most widely used disease-modifying anti-rheumatic drug (DMARD) RA, and RGD peptide a targeting moiety inflammation. Upon near-infrared (NIR) irradiation, heat locally generated due to Au half-shells, release rate enhanced, delivering inflamed joints simultaneously. RA chronic inflammatory disease characterized by synovial inflammation in...
Background: The clinical effect of probiotics on irritable bowel syndrome (IBS) is still controversial. Aims: We aimed to evaluate the effects a probiotic mixture IBS symptoms and composition fecal microbiota in patients with diarrhea-dominant (D-IBS). Methods: Fifty D-IBS were randomized into placebo or (Lactobacillus acidophilus, Lactobacillus plantarum, rhamnosus, Bifidobacterium breve, lactis, longum, Streptococcus thermophilus 1.0×1010 CFU) groups. Treatment was taken daily for 8 weeks....
We find the realization of large converse magnetoelectric (ME) effects at room temperature in a hexaferrite Ba0.52Sr2.48Co2Fe24O41 single crystal, which rapid change electric polarization low magnetic fields (about 5 mT) is coined to ME susceptibility 3200 ps/m. The modulation magnetization then reaches up 0.62μ(B)/f.u. an field 1.14 MV/m. further that four states induced by different poling exhibit unique, nonvolatile versus curves, can be approximately described effective free energy with...
Transparent oxides are essential building blocks to many technologies, ranging from components in transparent electronics, conductors, absorbers and protection layers photovoltaics photoelectrochemical devices. However, thus far, it has been difficult develop p-type with wide band gap high hole mobility; current state-of-art have mobility the range of < 10 cm$^2$/Vs, much lower than their n-type counterparts. Using high-throughput computational screening guide discovery novel mobility, we...
Reactive oxygen species (ROS) are an indispensable element of cellular signal transduction in various cell types, including bone cells. In particular, osteoclasts (OCs), cells specialized for resorption, utilize ROS as second messengers during receptor activator NF-κB ligand (RANKL)-induced differentiation and activation. addition, because the high energy demands bone-resorbing activity, OCs contain large amounts mitochondria, source majority total ROS. this study, we focused on regulation...
Rationale: Neuroinflammation is a primary feature of Alzheimer's disease (AD), for which an increasing number drugs have been specifically developed. The present study aimed to define the therapeutic impact specific subpopulation T cells that can suppress excessive inflammation in various immune and inflammatory disorders, namely, CD4+CD25+Foxp3+ regulatory (Tregs). Methods: To generate Aβ antigen-specific Tregs (Aβ+ Tregs), 1-42 peptide was applied vivo subsequent vitro splenocyte culture....
We studied the relationship between mobility and dislocation density for recently discovered high-mobility Ba0.96La0.04SnO3 thin-films found that carrier of film, as high 4.0×1020 cm−3 70 cm2 V−1s−1, respectively, decreased increased. determined values using transmission electron microscopy atomic force after surface etching. effect dislocations on was large, when compared with GaN a similar density. The importance scattering in perovskite structure is emphasized, especially...
Nanofiber microspheres have attracted a lot of attention for biomedical applications because their injectable and biomimetic properties. Herein, we report the first time new method fabrication nanofiber by combining electrospinning electrospraying explore potential cell therapy. Electrospraying aqueous dispersions electrospun segments with desired length obtained either cryocutting or homogenization into liquid nitrogen followed freeze-drying thermal treatment can form microspheres. The...
We report the growth of Ba1−xLaxSnO3 (x = 0.00, 0.005, 0.01, 0.02, and 0.04) thin films on insulating BaSnO3(001) substrate by pulsed laser deposition. The BaSnO3 substrates were grown Cu2O-CuO flux, in which molar fraction KClO4 was systematically increased to reduce electron carriers thus induce a doping induced metal-insulator transition, exhibiting resistivity increase from ∼10−3 ∼1012 Ω cm at room temperature. find that all are epitaxial, showing good in-plane lattice matching with as...
Assembling electrospun nanofibers with controlled alignment into three-dimensional (3D), complex, and predesigned shapes has proven to be a difficult task for regenerative medicine. Herein, we report novel approach inspired by solids of revolution that transforms two-dimensional (2D) nanofiber mats thickness once-inaccessible 3D objects shapes. The are highly porous, consisting layers aligned separated gaps ranging from several micrometers millimeters. Upon compression, the able recover...
Metastasis to bone is a frequent occurrence in patients with breast and prostate cancers inevitably threatens the patient's quality of life survival. Identification cancer-derived mediators metastasis osteolysis may lead novel therapeutic strategies. In this study, we established highly bone-metastatic PC3 MDA-MB-231 (MDA) cancer cell sublines by vivo selection mice. cells, expression secretion connective tissue growth factor (CTGF) were upregulated. CTGF knockdown cells decreased invasion...
We studied the conduction mechanism in Sb-doped BaSnO3 epitaxial films, and compared its behavior with that of counterpart, La-doped BaSnO3. found electron mobility films was reduced by almost 7 times when dopant changed from La to Sb, despite little change effective mass carriers. This indicates scattering rate electrons system is strongly affected site at which dopants are located. More importantly, we threading dislocations also depends critically on site. propose large enhancement caused...
The differentiation of osteoclasts, cells specialized for bone resorption, is governed by two key factors, macrophage colony stimulating factor (M-CSF) and receptor activator nuclear kappaB ligand (RANKL). extracellular matrix (ECM) an important influencing cell fate. To date, little investigation on the relationship between ECM components osteoclast has been documented. In this study, we uncovered a potent anti-osteoclastogenic effect hyaluronan (HA), component present in marrow soft...