A5070628179- Acupuncture Treatment Research Studies
- Complementary and Alternative Medicine Studies
- Traditional Chinese Medicine Studies
- Healthcare and Venom Research
- Pain Management and Placebo Effect
- Food Quality and Safety Studies
- Organic Electronics and Photovoltaics
- Diverse Approaches in Healthcare and Education Studies
- Organic Light-Emitting Diodes Research
- Phytochemicals and Antioxidant Activities
- Psychosomatic Disorders and Their Treatments
- Conducting polymers and applications
- Pain Mechanisms and Treatments
- Musculoskeletal pain and rehabilitation
- Myofascial pain diagnosis and treatment
- Acute Ischemic Stroke Management
- Education and Learning Interventions
- Dermatology and Skin Diseases
- Spine and Intervertebral Disc Pathology
- Health Systems, Economic Evaluations, Quality of Life
- Psychology of Moral and Emotional Judgment
- Agricultural Engineering and Mechanization
- Agriculture, Soil, Plant Science
- Neuroscience and Neural Engineering
- Semiconductor materials and devices
Catholic University of Korea
2024-2025
German Cancer Research Center
2023-2024
Heidelberg University
2023-2024
Jaseng Medical Foundation
2021-2024
Korea Institute of Oriental Medicine
2009-2024
Chungnam National University
2018-2023
Hanbat National University
2020-2023
Mercer University
2023
Mercer University Health Sciences Center
2023
APC Microbiome Institute
2022
Rationale: Neuroinflammation is a primary feature of Alzheimer's disease (AD), for which an increasing number drugs have been specifically developed. The present study aimed to define the therapeutic impact specific subpopulation T cells that can suppress excessive inflammation in various immune and inflammatory disorders, namely, CD4+CD25+Foxp3+ regulatory (Tregs). Methods: To generate Aβ antigen-specific Tregs (Aβ+ Tregs), 1-42 peptide was applied vivo subsequent vitro splenocyte culture....
Abstract Objective To promote better reporting quality regarding sham acupuncture in clinical trials for a precise appraisal of the adequacy procedure. Methods A three‐stage online Delphi survey was conducted to group experts. Items with higher than 80% consensus from initial checklist were selected as final candidates. Further discussion among working convened preclude potential redundancy items. Results total 23 experts out 35 (66%) responded process. The consists items six categories:...
Bacterial cell wall assembly and remodeling require activities of peptidoglycan (PG) hydrolases as well PG synthases. In particular, the activity DD-endopeptidases, which cleave 4-3 peptide crosslinks in PG, is essential for expansion gram-negative bacteria. Maintaining optimal levels DD-endopeptidases critical expanding without compromising its integrity. Escherichia coli , major MepS MepH, along with lytic transglycosylase MltD, are controlled by periplasmic protease Prc outer membrane...
The gut microbiota communicates with the brain through several pathways including vagus nerve, immune system, microbial metabolites and endocrine system. Pathways along humoral/immune microbiota-brain axis are composed of a series vascular epithelial barriers intestinal barrier, gut-vascular blood-brain barrier blood-cerebrospinal fluid barrier. Of these barriers, relationship between is yet to be fully defined. Here, using germ-free mouse model, we aimed assess integrity which localized...
The emotion-associated bodily sensation map is composed of a specific topographical distribution sensations to categorical emotions. present study investigated whether or not interoceptive accuracy was associated with changes in this following emotion-induced sensations. This included 31 participants who observed short video clips containing emotional stimuli and then reported their on the body map. Interoceptive evaluated heartbeat detection task spatial patterns emotions, including anger,...
Background . Korean medicine was incorporated into the Classification of Diseases (KCD) 6 through development U codes (U20–U99). Studies burden disease have used summary measures such as disability‐adjusted life years. Although is included in official health care system, studies that include are lacking. Methods A data‐based approach with National Health Insurance Service‐National Sample Cohort data for year 2012. code diagnoses patients covered by were collected. Using main and subdisease...
Bee venom phospholipase A2 is a lipolytic enzyme in bee that catalyzes hydrolysis of the sn-2 ester bond membrane phospholipids to produce free fatty acid and lysophospholipids. Current evidence suggests (bvPLA2) induces regulatory T cell expansion attenuates several immune system-related diseases, including Alzheimer’s disease. The induction Treg cells directly mediated by binding mannose receptors on dendritic cells. This interaction PGE2-EP2 signaling pathway, which promotes CD4+ In this...
Objective . Because individual acupoints have a wide variety of indications, it is difficult to accurately identify the associations between and specific diseases. Thus, present study aimed at revealing commonality specificity acupoint selections using virtual medical diagnoses based on several cases. Methods Eighty currently practicing Korean Medicine doctors were asked prescribe for acupuncture treatment after being presented with information extracted from 10 case reports. The prescribed...
Background The growing popularity of traditional medicine (TM) is reflected in the increasing trend for its use worldwide. Many people are turning to TM as a complementary or integrative treatment. aim this study present first nationwide report describing two countries (South Korea and Taiwan). Materials methods To utilization patterns between South Taiwan, we analyzed data from National Health Insurance cohorts each country, which has approximately one million inhabitants. Results In total,...
Three new phenolic compounds, (E)-4′-demethyl-6-methyleucomin (1), anemarcoumarin A (2), and anemarchalconyn (3), were isolated from an ethyl acetate extract of the rhizomes Anemarrhena asphodeloides, together with seven known compounds (4−10). The structures (1−3) determined on basis spectroscopic data interpretation. Compound 3 exhibited a potent inhibitory effect against differentiation preadipocyte 3T3-L1 cells IC50 value 5.3 μM.
Throughout the history of East Asian medicine, different kinds acupuncture treatment experiences have been accumulated in classical medical texts. Reexamining knowledge from texts is expected to provide meaningful information that could be utilized current practices. In this study, we used data mining methods analyze association between acupoints and patterns disorder with book DongUiBoGam Korean medicine. Using term frequency-inverse document frequency (tf-idf) method, quantified...
Every acupoint has specific indications for acupuncture treatment. These indications, primarily established based on the meridian system, have spatial patterns of symptoms human body. We investigated associations between acupoints and symptom locations in 75 patients with chronic pain who were asked to sketch localization their body schemes using bodily sensation map (BSM) system. Combining BSM clinical information, we estimated statistical parameters relationships information symptoms....
Parkinson's disease (PD) is a multilayered progressive brain characterized by motor dysfunction and variety of other symptoms. Although acupuncture has been used to ameliorate various symptoms neurodegenerative disorders, including PD, the underlying mechanisms are unclear. Here, we investigated mechanism revealing effects treatment on neural responses its functional connectivity in an animal model PD. We observed that destruction neuronal network between many regions PD mice were reversed...
Placebo analgesia can be primarily explained by the Pavlovian conditioning paradigm in which a passively applied cue becomes associated with less pain. In contrast, instrumental employs an active that might more similar to clinical settings. present study, involving modified trust game simulated situation was used induce placebo analgesia. Additionally, Bayesian modeling predict responses of individuals based on their choices. Twenty-four participants engaged medical decisions receive...