A5016206637- Parkinson's Disease Mechanisms and Treatments
- Neurological disorders and treatments
- Genetic Neurodegenerative Diseases
- Restless Legs Syndrome Research
- Cerebrovascular and Carotid Artery Diseases
- Cardiovascular Health and Disease Prevention
- Botulinum Toxin and Related Neurological Disorders
- Neurological and metabolic disorders
- Acute Ischemic Stroke Management
- Parkinson's Disease and Spinal Disorders
- Obsessive-Compulsive Spectrum Disorders
- Psychosomatic Disorders and Their Treatments
- Lysosomal Storage Disorders Research
- Glycogen Storage Diseases and Myoclonus
- Cerebral Palsy and Movement Disorders
- Dysphagia Assessment and Management
- Mitochondrial Function and Pathology
- Medication Adherence and Compliance
- Blood Pressure and Hypertension Studies
- Scoliosis diagnosis and treatment
- Stroke Rehabilitation and Recovery
- Biochemical Analysis and Sensing Techniques
- Migraine and Headache Studies
- Nuclear Receptors and Signaling
- Health Systems, Economic Evaluations, Quality of Life
Inje University Sanggye Paik Hospital
2015-2024
Sejong University
2024
Ansan University
2023
Korea University
2023
Inje University
2006-2019
Baikal Institute of Nature Management
2019
Yonsei University
1997-2014
Toronto Western Hospital
2007
This study was designed to evaluate cerebral hemodynamic changes related diabetes mellitus (DM) with transcranial Doppler ultrasonography (TCD).We measured the flow velocities and Gosling pulsatility index (PI) of middle artery (MCA), extracranial internal carotid (ICA), basilar (BA) in 56 stroke-free, normotensive patients type 2 DM 70 age- gender-matched healthy volunteers. Patients were divided into groups according presence microvascular complications such as retinopathy, nephropathy,...
Abstract An abnormal gait is not uncommon in patients with medically unexplained neurological symptoms, including those other psychogenic movement disorders (PMDs). Previous studies have evaluated the characteristics of a variety PMDs and there are no reports comparing without disturbances. We were interested determining how additional involvement differed PMD from pure disorder (PGD) absence another PMD. investigated features large series (n = 279), dividing them into two groups (Group I...
Non-motor symptoms are common in Parkinson's disease (PD), and the primary cause of disability many PD patients. Our aim this study was to translate origin non-motor scale for (NMSS), which written English, into Korean (K-NMSS), evaluate its reliability validity use with Korean-speaking patients PD.In total, 102 from 9 movement disorders sections university teaching hospitals Korea were enrolled study. They assessed using K-NMSS, Unified Disease Rating Scale (UPDRS), version Mini-Mental...
Prospective study.Our objectives were to evaluate the prevalence of sagittal spinopelvic malalignment in a consecutive series patients with Parkinson disease (PD) and identify factors associated deformity this population.PD is degenerative neurological condition characterized by tremor, rigidity, bradykinesia, loss postural reflexes. The spinal PD higher than that age-matched adults without PD.This study was prospective assessment presenting neurology clinic during 12 months. Inclusion...
Autonomic symptoms are commonly observed in patients with Parkinson's disease (PD) and often limit the activities of daily living. The Scale for Outcomes disease-Autonomic (SCOPA-AUT) was developed to evaluate quantify autonomic PD. goal this study translate original SCOPA-AUT, which written English, into Korean its reliability validity PD patients.For translation, following processes were performed: forward backward expert review, pretest pre-final version development final SCOPA-AUT...
Scoliosis is more common in patients with Parkinson's disease (PD) than the general elderly population. We compared clinical characteristics between PD and without scoliosis, to identify relationship direction of scoliosis laterality dominant symptoms PD. also studied associations dopaminergic pharmacotherapy (defined by a spinal curvature deviation 10 degrees or larger).The study population comprised 97 (42 men 55 women) idiopathic All submitted whole-spine scanograph allow measurement...
Background: Postural instability is one of the most disabling features Parkinson's disease, usually occurring in late and advanced stages. The aim this study was to investigate postural performance early-stage de novo disease patients with no clinical using computerized dynamic posturography. We sought understand relationship between sway severity quantitatively measured by posturography cognitive impairment patients. Method: Thirty-one subjects 20 healthy controls were assessed protocol...
Increasing levodopa (L-dopa)/dopa decarboxylase inhibitor (DDCI) daily dose or adding a catechol-O-methyltransferase (COMT) to levodopa/DDCI therapy are strategies used manage wearing-off symptoms in Parkinson's disease (PD) patients.
The importance of health-related quality life (HrQoL) has been increasingly emphasized when assessing and providing treatment to patients with chronic, progressive, degenerative disorders. 39-item Parkinson's disease questionnaire (PDQ-39) is the most widely used patient-reporting scale assess HrQoL in (PD). This study evaluated validity reliability translated Korean version PDQ-39 (K-PDQ-39).One hundred two participants PD from 10 movement disorder clinics at university-affiliated hospitals...
ObjectiveaaHuntington's disease (HD) is a rare neurological disorder, and its current status in Korea not well investigated.This study aims to determine the prevalence incidence of HD investigate clinical features patients Korea.MethodsaaWe estimated crude annual based on databases Rare Diseases Registry (RDR) National Health Insurance (NHI).The data genetically confirmed was collected from 10 referral hospitals analyzed.ResultsaaThe mean calculated 0.06 cases per 100,000 persons, 0.38 NHI...
ABSTRACT BACKGROUND AND PURPOSE Atherosclerosis and osteoporosis are two major public health problems. It is still uncertain whether an abnormal carotid ultrasonography, either increased intima‐media thickness (IMT) or plaque thickness, associated with in acute ischemic stroke patients. To investigate the possible relationships between atherosclerosis, we evaluated correlation IMT/plaque bone mineral density (BMD) METHODS Patients having their first within seven days were screened for study....
To identify the characteristics of cervical deformities in Parkinson's disease (PD) and role severity PD development spine deformities, authors investigated prevalence kyphosis (CK), positive sagittal malalignment (CPSM) patients with PD. They also analyzed association stage context global spinopelvic alignment.This study was a prospective assessment consecutively treated (n = 89) A control group age- sex-matched selected from degenerative but without Clinical demographic parameters...
Nonmotor symptoms (NMS) in Parkinson's disease (PD) have multisystem origins with heterogeneous manifestations that develop throughout the course of PD. NMS are increasingly recognized as having a significant impact on health-related quality life (HrQoL). We aimed to determine presentation according PD status, and associations other clinical variables HrQoL Korean patients.We surveyed patients 37 movement-disorders clinics Korea. In total, 323 were recruited for assessment severity duration,...
Objective In this multicentre open-label trial, we compared behavioural and neuropsychiatric symptoms in Parkinson’s disease (PD) patients with impulse control disorders (ICD) treated dopamine agonists before 12 weeks after substituting an equivalent dose of levodopa/carbidopa slow-release formulation. Methods Baseline characteristics 50 PD ICD were those 60 medicated 40 drug-naive groups. Neuropsychiatric trait changes the PD-ICD group investigated intervention. behaviours assessed via...
Abstract We describe a 46‐year‐old woman who presented with lingual dystonia induced only by speaking, which responded well to anticholinergic treatment. © 2004 Movement Disorder Society
ABSTRACT BACKGROUND AND PURPOSE We investigated the relationship between transcranial Doppler (TCD) pulsatility index (PI) and central aortic pressure by measurement of augmentation (AIx). METHODS enrolled 148 consecutive patients with a diagnosis acute ischemic stroke. Patients were eligible for study if they experienced their first stroke within preceding 7 days 45 years age or older. At Day (±2) after onset, TCD studies performed AIx was measured applanation tonometry on same days....