A5034585140- Parkinson's Disease Mechanisms and Treatments
- Neurological disorders and treatments
- Acute Ischemic Stroke Management
- Stroke Rehabilitation and Recovery
- Intracerebral and Subarachnoid Hemorrhage Research
- Vascular Malformations Diagnosis and Treatment
- Restless Legs Syndrome Research
- Neurological Disorders and Treatments
- Face Recognition and Perception
- Olfactory and Sensory Function Studies
- Neurological and metabolic disorders
- Facial Nerve Paralysis Treatment and Research
- Glycogen Storage Diseases and Myoclonus
- Brain Tumor Detection and Classification
- Functional Brain Connectivity Studies
- Pesticide Exposure and Toxicity
- Cerebral Venous Sinus Thrombosis
- Ophthalmology and Eye Disorders
- Protein Tyrosine Phosphatases
- Vascular anomalies and interventions
- Epilepsy research and treatment
- Pathogenesis and Treatment of Hiccups
- Multimodal Machine Learning Applications
- Effects of Vibration on Health
- Medical Imaging and Analysis
Korea University
2014-2024
Kyungpook National University
2019-2024
Ansan University
2015-2024
University of Nevada, Las Vegas
2021
Soongsil University
2021
Catholic University of Korea
2014-2021
Suwon Catholic University
2014
To investigate the longitudinal association among high-density lipoprotein cholesterol (HDL-C) level, HDL-C variability, and risk of developing Parkinson disease (PD).We conducted a nationwide, population-based cohort study. We included 382,391 patients aged ≥65 years who underwent at least 3 health examinations provided by Korean National Health Insurance System from 2008 to 2013 followed up until 2017. Individuals with history PD missing values were excluded (n = 1,987). assessed...
Increasing levodopa (L-dopa)/dopa decarboxylase inhibitor (DDCI) daily dose or adding a catechol-O-methyltransferase (COMT) to levodopa/DDCI therapy are strategies used manage wearing-off symptoms in Parkinson's disease (PD) patients.
A "masked face", that is, decreased facial expression is considered as one of the cardinal symptoms among individuals with Parkinson's disease (PD). Both spontaneous and voluntary mimicry toward others' emotional expressions essential for both social communication sharing others. Despite many studies showing impairments in movements PD general, it still unclear whether voluntary, spontaneous, or types are affected how affect patients' quality life. We investigated to verify happen well by...
The aim of this study was to investigate the prescribing cascade phenomenon dopaminergic drugs such as levodopa in management gastroprokinetic induced parkinsonism. Based on Korea National Health Insurance Service (NHIS)-Senior Cohort Database, we analyzed patients aged ≥65 years, between 2009 and 2013, who obtained new prescriptions for through NHIS during period. Those were prescribed from 2002 2008 excluded, only metoclopramide levosulpiride within 90 days receiving prescription included....
The pathophysiology of post-stroke depression (PSD) is complex and may differ according to an individual's mood immediately after stroke. Here, we compared the therapeutic response clinical characteristics PSD at a later stage between patients with without stroke.This study involved post hoc analysis data from EMOTION (ClinicalTrials.gov NCT01278498), placebo-controlled, double-blind trial that examined efficacy escitalopram (10 mg/day) on other emotional disturbances among 478 acute...
The question whether facial expression processing may be impaired in Parkinson's disease (PD) patients so far has yielded equivocal results - existing studies, however, have focused on testing recognition tasks with static images of six standard, emotional expressions. Given that non-verbal communication contains both and non-emotional, conversational expressions input to the brain is usually dynamic, here we address potential differences a novel format: test range emotional, dynamic three...
Abstract This multicentre, prospective, single-arm study evaluated safinamide as add-on therapy to levodopa in Korean patients with Parkinson’s disease (PD) motor fluctuations ≥ 1.5 h of “off” time daily, who took 3 times/day ( n = 199). Baseline and dopamine agonist doses were maintained without escalation during the 18-week treatment period. Participants received 50 mg/day for 2 weeks 100 thereafter. PD diaries questionnaires (Parkinson’s Disease Questionnaire, PDQ-39; Movement Disorder...
Incomplete Atypical Femoral Fracture (IAFF) is a precursor to (AFF). If untreated, it progresses complete fracture, increasing mortality risk. However, due their small and ambiguous features, IAFFs are often misdiagnosed even by specialists. In this paper, we propose novel approach for accurately classifying in X-ray images across various radiographic views. We design Dual Context-aware Complementary Extractor (DCCE) capture both the overall femur characteristics IAFF details with...
Introduction: Although recurrent stroke is clinically important, prediction of less well known. Machine learning encompasses a body statistical approaches that can detect complex interaction patterns from multi-dimensional data. ML gradually being adopted in medical science. The purpose this study was to illustrate the possibility using machine as an aid stroke. Methods: We obtained clinical data consecutively registered, hospital-based acute registry. Using dataset 4,766 ischemic patients,...
A 57-year-old man who had a traffic accident 1 month previously presented with left ocular pain, double vision, and eye proptosis ptosis conjunctival hemorrhage. Fundus showed dilated veins no hemorrhages or disc edema. Left motility complete external ophthalmoplegia (figure 1). There was prominent bruit in his (audio file on the Neurology ® Web site at [Neurology.org][1]). MRI magnetic resonance angiography superior ophthalmic vein an extravasation into cavernous sinus 2). With chemosis,...
Classical HWW consist of an obstructed hemivagina in didelphic uterus with ipsilateral renal agenesis. Most cases were diagnosed at adolescents after menarche. Our case is a variant syndrome consisting septated agenesis which the diagnosis was delayed until pregnancy. The patient who carried pregnancy to term have Caesarean section because unilateral bulging vaginal pouch made birth difficult. baby and uneventful.
Background and hypothesis: Post-stroke emotional symptoms are common adversely influence the patients’ outcome. We aim to evaluate efficacy of escitalopram in patients with acute stroke for prevention various disorders, improvement neurologic, cognitive function patient quality life. Method: In this multicenter, placebo-controlled, double-blind trial, 405 (within 21 days after onset) were randomized either (n = 217) (5 mg -10mg) or placebo 188) 3 months. Depressive (Montgomery-Asberg...