A5040837657- Blood Pressure and Hypertension Studies
- Topic Modeling
- Natural Language Processing Techniques
- ECG Monitoring and Analysis
- Biomedical Text Mining and Ontologies
- Sodium Intake and Health
- Cardiac electrophysiology and arrhythmias
- Parkinson's Disease Mechanisms and Treatments
- Cardiac Imaging and Diagnostics
- Cardiovascular Function and Risk Factors
- Atrial Fibrillation Management and Outcomes
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Antibiotic Use and Resistance
- Liver Disease Diagnosis and Treatment
- Pharmaceutical Practices and Patient Outcomes
- Hormonal Regulation and Hypertension
- Antibiotic Resistance in Bacteria
- Lipoproteins and Cardiovascular Health
- Urinary Tract Infections Management
- Medication Adherence and Compliance
- Cardiovascular Disease and Adiposity
- Esophageal Cancer Research and Treatment
- Vestibular and auditory disorders
- Cardiac Arrhythmias and Treatments
- Heart Rate Variability and Autonomic Control
Korea University
2021-2024
Gangdong University
2024
Kyung Hee University Hospital at Gangdong
2024
Abstract With advances in deep learning and natural language processing (NLP), the analysis of medical texts is becoming increasingly important. Nonetheless, despite importance texts, no research on Korean medical-specific models has been conducted. The text highly difficult to analyze because agglutinative characteristics language, as well complex terminologies domain. To solve this problem, we collected a corpus used it train models. In paper, present model based NLP. was trained using...
In a 12-lead electrocardiogram (ECG) examination, the ECG signals often have low-quality data problems due to high-frequency noise caused by muscles and low-frequency body movement, breathing. These cause delays in examination results increase medical costs. For this reason, solving missing can provide patients with improved services, reducing work-loss The purpose of study is develop signal restoration model for each 12 solve mechanical operator errors during examinations. study, 13,862...
There are several differences in the clinical course of hypertension due to biological and social between men women. Resistant is an advanced disease state, significant gender difference could be expected, but much has not been revealed yet. The purpose this study was compare on current status blood pressure (BP) control prognosis patients with resistant hypertension.This a multicenter, retrospective cohort using common data model databases 3 tertiary hospitals Korea. Total 4,926 were...
Telmisartan exhibits superior efficacy in controlling 24-h blood pressure (BP) compared with other angiotensin receptor blockers (ARBs). However, data on its cardiovascular effects patients hypertension are limited. This study aimed to evaluate the outcomes taking telmisartan those ARBs.
Abstract An increase in antibiotic usage is considered to contribute the emergence of antimicrobial resistance. Although experts are counting on stewardship programs reduce usage, their effect remains uncertain. In this study, we aimed evaluate impact and forecast prevalence hospital-acquired extended spectrum β-lactamase (ESBL)—producing Escherichia coli ( E. ) using time-series analysis. Antimicrobial culture information was obtained a text processing technique that helped extract...
Aim Hearing loss, affecting a significant portion of the global population, is prevented with peroxisome proliferator-activated receptor γ agonism. Understanding potential protective treatments crucial for public health. We examine effect telmisartan, an antihypertensive drug and partial agonist, on hearing loss in patients hypertension. Method results This retrospective cohort analysis used data from OMOP Common Data Model database, encompassing information three tertiary institutions South...
Various single-pill combinations (SPCs) have been introduced to improve drug compliance and clinical efficacy. However, there is a lack of real-world evidence regarding the effectiveness these SPCs for hypertension. This study evaluated efficacy safety amlodipine/losartan-based SPC therapies in patients with hypertension setting. A total 15 538 treated [amlodipine + losartan (AL), amlodipine rosuvastatin (ALR), chlorthalidone (ALC)] were selected from database three tertiary hospitals Korea....
Abstract Background Hypertriglyceridemia is an important feature of dyslipidemia in type 1 and 2 diabetic patients associated with the development atherosclerotic cardiovascular disease. Recently, variability lipid profile has been suggested as a residual risk factor for This study compared clinical impact serum triglyceride variability, their cumulative exposure estimates on prognosis patients. Methods A total 25,933 who had levels measured at least 3 times did not have underlying...
This study aims to evaluate the accuracy and effectiveness of real-time personal monitoring exposure PM concentrations using low-cost sensors, in comparison conventional data collection method based on fixed stations. PM2.5 were measured every 5 min a sensor attached bag carried by 47 asthmatic children living Seoul Metropolitan area between November 2019 March 2020, along with GPS location, temperature, humidity. The mobile then matched station-based hourly time location. Despite some...
Background Improved prediction of atrial fibrillation (AF) may allow for earlier interventions stroke prevention, as well mortality and morbidity from other AF-related complications. We developed a clinically feasible accurate AF model using electronic health records computerized ECG interpretation. Methods Results A total 671 318 patients were screened 3 tertiary hospitals. After careful exclusion cases with missing values prior diagnosis, models the derivation cohort 25 584 without at...
Compared with placebo, olmesartan has been linked to numerical imbalances in cardiovascular mortality. There is a paucity of contemporary real-world evidence on this agent for different study populations. This investigated the clinical outcomes and other antihypertensives patients advanced hypertension.This multicenter retrospective used data from Korea University Medical Center database, built electronic health records. Patients prescribed at least two antihypertensive medications as...
Objective: In the growing population of older patients with hypertension, limited evidence supports an association between lowering systolic blood pressure (SBP) and decreased adverse events. We aimed to investigate cardiovascular outcomes according on-treatment SBP in hypertensive patients. Methods: This multicenter, retrospective study used data from Korea University Medical Center database built on electronic health records 2017 2022. Patients initiated at least two antihypertensive drugs...
Background The fact that medical terms require special expertise and are becoming increasingly complex makes it difficult to employ natural language processing techniques in informatics. Several human-validated reference standards for have been developed evaluate word embedding models using the semantic similarity relatedness of pairs. However, there very few non-English languages. In addition, because existing were a long time ago, is need develop an updated standard represent recent...
Abstract Background Chronic kidney disease (CKD) is a strong risk factor for cardiovascular disease. Electrocardiogram (ECG) the basic test screening However, impact of ECG abnormalities on prognosis in patients with CKD largely unknown. Methods A total 1,295 (stage 3, 4, and 5) who underwent between 2013 2015 were selected from tertiary hospital Korea. defined using Minnesota classification. Five-year major adverse cerebrocardiovascular event (MACCE), composite death, myocardial infarction...
Chronic kidney disease (CKD) is a strong risk factor for cardiovascular disease. An electrocardiogram (ECG) basic test screening However, the impact of ECG abnormalities on prognosis in patients with CKD largely unknown. A total 2442 (stages 3–5) who underwent between 2013 and 2015 were selected from electronic health record database Korea University Anam Hospital. defined using Minnesota classification. The five-year major adverse cerebrocardiovascular event (MACCE), composite death,...
Objective: There is limited evidence of the growing population elderly patients with hypertension, particularly relationship between blood pressure (BP) and adverse outcomes. We sought to estimate outcomes according attained BP in treated for moderate hypertension. Design method: This multicenter, retrospective study used Korea University Medical Center database built on electronic health records from 2017 2020. Patients initiated at least two antihypertensive drugs as combined therapy were...
Objective: Olmesartan has been linked to numerical imbalances of cardiovascular mortality compared placebo group. There is a paucity contemporary data on real world evidence this agent in different study populations. We sought investigate clinical outcomes between olmesartan and other anti-hypertensive medications moderately hypertensive patients. Design method: This multicenter, retrospective used the Korea University Medical Center database built electronic health records from 2017 2020....
Objectives: Electrocardiography (ECG)-based diagnosis by experts cannot maintain uniform quality because individual differences may occur. Previous public databases can be used for clinical studies, but there is no common standard that would allow to combined. For this reason, it difficult conduct research derives results combining databases. Recent commercial ECG machines offer diagnoses similar those of a physician. Therefore, the purpose study was construct standardized database using...
Objective: Background Telmisartan have potent blood pressure lowering effect as well the other pleiotrophic effects including PPAR-??/?? dual activation. In large clinical studies, telmisartan demonstrated comparable benefits with angiotensin converting enzyme inhibitor. However, there were few studies of direct comparison between and receptor blockers (ARBs). This study aimed to compare cardiovascular renal protective ARBs in patients advanced hypertension who required two or more...