A5100698573- Bacterial Identification and Susceptibility Testing
- SARS-CoV-2 and COVID-19 Research
- Antimicrobial Resistance in Staphylococcus
- COVID-19 Clinical Research Studies
- Orthopaedic implants and arthroplasty
- Antibiotic Resistance in Bacteria
- Hip and Femur Fractures
- Mycobacterium research and diagnosis
- Bone fractures and treatments
- Orthopedic Infections and Treatments
- Infectious Diseases and Tuberculosis
- HIV/AIDS drug development and treatment
- Pneumocystis jirovecii pneumonia detection and treatment
- Orthopedic Surgery and Rehabilitation
- Pneumonia and Respiratory Infections
- Fungal Infections and Studies
- Antibiotic Use and Resistance
- Hip disorders and treatments
- Total Knee Arthroplasty Outcomes
- Urinary Tract Infections Management
- Bone Tissue Engineering Materials
- Tuberculosis Research and Epidemiology
- Antifungal resistance and susceptibility
- Clostridium difficile and Clostridium perfringens research
- Long-Term Effects of COVID-19
Boramae Medical Center
2016-2025
Seoul National University
2016-2025
Kyungpook National University
2019-2025
Seoul Metropolitan Government
2011-2024
Catholic University of Korea
1995-2024
Sejong General Hospital
2023-2024
Seoul National University Hospital
1999-2024
Uijeongbu St. Mary's Hospital
2024
Bundang Jesaeng Hospital
2024
National Cancer Institute
2003-2023
Highly efficient quantum-dot-sensitized solar cell is fabricated using ca. 2–3 nm sized perovskite (CH3NH3)PbI3 nanocrystal. Spin-coating of the equimolar mixture CH3NH3I and PbI2 in γ-butyrolactone solution (perovskite precursor solution) leads to quantum dots (QDs) on nanocrystalline TiO2 surface. By electrochemical junction with iodide/iodine based redox electrolyte, QD-sensitized 3.6 μm-thick film shows maximum external efficiency (EQE) 78.6% at 530 solar-to-electrical conversion 6.54%...
The loss of muscle mass is considered to be a major determinant strength in aging. However, large-scale longitudinal studies examining the association between and older adults are lacking.Three-year changes were determined 1880 Health, Aging Body Composition Study. Knee extensor was measured by isokinetic dynamometry. Whole body appendicular lean fat assessed dual-energy x-ray absorptiometry computed tomography.Both men women lost strength, with losing almost twice as much women. Blacks...
Among the nosocomial pathogens, Pseudomonas aeruginosa is recognized as a major cause of morbidity and mortality. Data on 136 patients with P. bacteremia were retrospectively analyzed to evaluate risk factors for The median age was 55 years (range, 15-85 years), 78.7% cases hospital-acquired, 30-day mortality rate 39% (53 patients). Multivariate analysis demonstrated that included severe sepsis, pneumonia, delay in starting effective antimicrobial therapy, an increasing APACHE II score (all...
Abstract We investigated the kinetics of Middle East respiratory syndrome coronavirus (MERS-CoV) neutralizing and spike protein antibody titers over course 1 year in 11 patients who were confirmed by reverse transcription PCR to have been infected during outbreak South Korea 2015. Robust responses detected all survivors had severe disease; remained detectable, albeit with some waning, for <1 year. The duration viral RNA detection (but not load) sputum significantly correlated response...
Clinical Progression and Cytokine Profiles of Middle East Respiratory Syndrome Coronavirus InfectionClinical progression over time cytokine profiles have not been well defined in patients with respiratory syndrome coronavirus (MERS-CoV) infection.We included 17 laboratory-confirmed MERS-CoV during the 2015 outbreak Korea.Clinical laboratory parameters were collected prospectively.Serum chemokine levels serial serum samples measured using enzyme-linked immunosorbent assay.All presented...
Advances in the diagnosis and management of acute ischemic stroke (AIS) increased use mechanical thrombectomy (MT) have improved quality care prognosis patients with AIS since 2015. We investigated changing trends mortality Korea before after A retrospective cohort study was conducted using combined anonymized data from Acute Stroke Assessment Registry Health Insurance Review & Service database. Patients precise onset time initial National Institute Scale records were included. receiving MT...
Glycyrrhizin is the major active component extracted from licorice (Glycyrrhiza glabra) roots, one of most widely used herbal preparations for treatment liver disorders. This study evaluated potential beneficial effect glycyrrhizin in a mouse model carbon tetrachloride (CCl4)-induced injury. The mice were treated intraperitoneally with CCl4 (0.5 ml/kg). They received (50, 100, 200, 400 mg/kg) 24 h and 0.5 before 4 after administering CCl4. serum activities aminotransferase hepatic level...
Severe fever with thrombocytopenia syndrome (SFTS) is an emerging infectious disease that was recently identified in China, South Korea and Japan. The objective of the study to evaluate epidemiologic clinical characteristics SFTS Korea.SFTS a reportable Korea. We included all cases reported Centers for Disease Control Prevention (KCDC) from January 2013 December 2015. Clinical information gathered by reviewing medical records, were analyzed using both KCDC surveillance data patient records....
Abstract We investigated the kinetics of serologic responses to Middle East respiratory syndrome coronavirus (MERS-CoV) infection by using virus neutralization and MERS-CoV S1 IgG ELISA tests. In most patients, robust antibody developed third week illness. Delayed with test were associated more severe disease.
We investigated the kinetics of severe acute respiratory syndrome coronavirus 2 neutralizing antibodies in 7 asymptomatic persons and 11 patients with pneumonia. The geometric mean titer declined from 219.4 at months to 143.7 5 after infection, indicating a waning antibody response.
About 20% of methicillin-susceptible Staphylococcus aureus (MSSA) isolates have a substantial inoculum effect with cefazolin, suggesting that cefazolin treatment may be associated clinical failure for serious MSSA infections. There are no well-matched controlled studies comparing nafcillin the bacteremia. A retrospective propensity-score-matched case-control study was performed from 2004 to 2009 in tertiary care hospital where unavailable August 2006. The group (n = 49) included...
This nationwide, prospective cohort study evaluated pulmonary function and radiological sequelae according to infection severity in 73 survivors from the 2015 Middle East respiratory syndrome (MERS) outbreak Korea.Patients with severe pneumonia MERS-coronavirus had more impaired than those no or mild at 1-year follow-up, which was compatible sequelae.Severe significantly impairs makes long MERS.
Clinical and Epidemiologic Characteristics of Spreaders Middle East Respiratory Syndrome Coronavirus during the 2015 Outbreak in Korea Nosocomial transmission is an important characteristic (MERS-CoV) infection.Risk factors for MERS-CoV healthcare settings are not well defined.During Korean outbreak 2015, 186 patients had laboratory-confirmed infection.Those suspected as a source viral were categorized into spreader groups (super-spreader [n = 5] usualspreader 10]) compared to non-spreader...
Background Scrub typhus is an endemic disease in Asia. It has been a rural disease, but indigenous urban cases have observed Seoul, South Korea. Urban scrub may significant impact because of the large population. Methods Indigenous was epidemiologically identified largest metropolitan city Korea, using national notifiable data from 2010 to 2013. For detailed analysis clinical features, patients one hospital that reported majority were selected and compared historic control group. Chigger...
Staphylococcus aureus, one of the most frequently isolated pathogens in both hospitals and community, has been particularly efficient at developing resistance to antimicrobial agents. As methicillin-resistant S. aureus (MRSA) prevailed and, furthermore, as with reduced susceptibility vancomycin emerged, therapeutic options for treatment infections have become limited. To update current status antibiotic resistance, clinical isolates were collected from eight university-affiliated June 1999...
Background. Persistent methicillin-resistant Staphylococcus aureus (MRSA) bacteremia is associated with high mortality rates, but no treatment strategy has yet been established. We performed this study to evaluate the efficacy of linezolid or without carbapenem in salvage for persistent MRSA bacteremia.
We performed a retrospective review of 126 cases infectious spondylodiscitis over 4-year period.Differentiation between pyogenic (PS) and tuberculous (TS) is essential for deciding on the appropriate therapeutic regimen. The aim this study was to compare characteristics 2 forms spondylodiscitis.There has been much effort distinguish radiologic findings in PS versus TS, but classification based alone had limitations yet.We compared predisposing factors or associated illnesses, clinical,...
We retrospectively reviewed medical records to identify the factors that affect results of culture in patients with pyogenic vertebral osteomyelitis. In multivariate analysis, presence paravertebral abscess was associated positive microbiologic culture. Prior antibiotic exposure, especially longer duration, strongly negative results.
Asymptomatic bacteriuria (ABU) is common and often leads to unnecessary antimicrobial use. Reducing antibiotic overuse for ABU therefore an important issue stewardship. We performed this study investigate the appropriateness of management evaluate physicians' knowledge practice regarding ABU.We reviewed all urine cultures ≥10(5) cfu/mL bacteria among inpatients in a 900-bed hospital 2011. Each episode was classified into or urinary tract infection (UTI). defined as positive culture (≥10(5)...
Phages and their derivatives are increasingly being reconsidered for use in the treatment of bacterial infections due to rising rates antibiotic resistance. We assessed antistaphylococcal effect endolysin SAL200 combination with standard-of-care (SOC) antibiotics.