A5100689633- Antimicrobial Resistance in Staphylococcus
- Antibiotic Resistance in Bacteria
- Bacterial Identification and Susceptibility Testing
- SARS-CoV-2 and COVID-19 Research
- Spine and Intervertebral Disc Pathology
- Pneumonia and Respiratory Infections
- COVID-19 Clinical Research Studies
- Bacterial biofilms and quorum sensing
- Pneumocystis jirovecii pneumonia detection and treatment
- Respiratory viral infections research
- Bacterial Infections and Vaccines
- Oral and Maxillofacial Pathology
- Medical Imaging and Analysis
- Urinary Tract Infections Management
- Bone Tumor Diagnosis and Treatments
- Gastrointestinal disorders and treatments
- Health and Wellbeing Research
- Vector-borne infectious diseases
- Streptococcal Infections and Treatments
- Antibiotics Pharmacokinetics and Efficacy
- Spinal Fractures and Fixation Techniques
- Salmonella and Campylobacter epidemiology
- Infectious Diseases and Tuberculosis
- Viral gastroenteritis research and epidemiology
- Antibiotic Use and Resistance
Chungnam National University Hospital
2014-2024
Chungnam National University
2015-2024
Hanyang University
2006-2024
Chung-Ang University
2015-2024
Yonsei University
1996-2024
Kyungpook National University
2005-2024
University of Edinburgh
2024
Inje University Busan Paik Hospital
2023
Seoul National University
2006-2023
Biobase (Germany)
2023
The antibacterial effect and mechanism of action a silver ion solution that was electrically generated were investigated for Staphylococcus aureus Escherichia coli by analyzing the growth, morphology, ultrastructure bacterial cells following treatment with solution. Bacteria exposed to various lengths time, tested using conventional plate count method flow cytometric (FC) analysis. Reductions more than 5 log(10) CFU/ml both S. E. bacteria confirmed after 90 min Significant reduction also...
Simplified regimens for the treatment of human immunodeficiency virus type 1 (HIV-1) infection may increase patient satisfaction and facilitate adherence.In this phase 3, open-label, multicenter, noninferiority trial involving patients who had plasma HIV-1 RNA levels less than 50 copies per milliliter at least 6 months while taking standard oral antiretroviral therapy, we randomly assigned participants (1:1) to either continue their therapy or switch monthly intramuscular injections...
Methicillin-resistant Staphylococcus aureus (MRSA) is highly prevalent in hospitals many Asian countries. Recent emergence of community-associated (CA) MRSA worldwide has added another serious concern to the epidemiology S. infections. To understand changing infections countries, we performed a prospective, multinational surveillance study with molecular typing analysis.We evaluated prevalence methicillin resistance isolates CA and healthcare-associated (HA) infections, characterization...
Abstract Despite the ongoing spread of MERS, there is limited knowledge factors affecting its severity and outcomes. We analyzed clinical data specimens from fourteen MERS patients treated in a hospital who collectively represent wide spectrum disease severity, ranging mild febrile illness to fatal pneumonia, classified into four groups based on mortality. Comparative kinetic analyses revealed that high viral loads, weak antibody responses, lymphopenia accompanying thrombocytopenia were...
In this study, an assay to quantify the presence of aluminum ions using a salicylimine-based receptor was developed utilizing turn-on fluorescence enhancement. Upon treatment with ions, sensor enhanced at 510 nm due formation 1:1 complex between chemosensor and room temperature. As concentration Al3+ increased, gradually increased. Other metal such as Na+, Ag+, K+, Ca2+, Mg2+, Hg2+, Mn2+, Co2+, Ni2+, Cu2+, Zn2+, Cd2+, Pb2+, Cr3+, Fe3+, In3+, had no significant effect on fluorescence....
The effects of convalescent plasma (CP) infusion, one the treatment options for severe Middle East respiratory syndrome coronavirus (MERS-CoV) infections, have not yet been evaluated.Serological responses CP-infused MERS patients during 2015 Korean outbreak at a tertiary care centre were evaluated. Serological activity was evaluated with anti-MERS-CoV enzyme-linked immunosorbent assay (ELISA) immunoglobulin (Ig)G, ELISA IgA, immunofluorescence IgM and plaque reduction neutralization test...
Antimicrobial resistance in Streptococcus pneumoniae remains a serious concern worldwide, particularly Asian countries, despite the introduction of heptavalent pneumococcal conjugate vaccine (PCV7). The Network for Surveillance Resistant Pathogens (ANSORP) performed prospective surveillance study 2,184 S. isolates collected from patients with infections 60 hospitals 11 countries 2008 to 2009. Among nonmeningeal isolates, prevalence rate penicillin-nonsusceptible pneumococci (MIC, ≥ 4 μg/ml)...
Hospital-acquired pneumonia (HAP) and ventilator-associated (VAP) remain important causes of morbidity mortality. Increasing antimicrobial resistance has aroused the concern failure antibiotic treatment.To determine distribution bacterial isolates HAP VAP, their patterns, impact discordant therapy on clinical outcome in Asian countriesA prospective surveillance study was conducted 73 hospitals 10 countries from 2008-2009. A total 2,554 cases with or VAP adults were enrolled 2,445 collected...
Observational studies of the ongoing coronavirus disease 2019 (COVID-19) outbreak suggest that a 'cytokine storm' is involved in pathogenesis severe illness. However, molecular mechanisms underlying altered pathological inflammation COVID-19 are largely unknown. We report here toll-like receptor (TLR) 4-mediated inflammatory signaling molecules upregulated peripheral blood mononuclear cells (PBMCs) from patients, compared with healthy controls (HC).
Starting gate: A molecular logic gate is based on chemosensors that change their fluorescence intensity in response to various inputs (pH, metal ions) a microfluidic system. combinatorial circuit, such as half adder (see picture), uses fluorescein (green) and rhodamine B (red) derivatives respond pH. with protein Cu2+ ions also described. Supporting information for this article available the WWW under http://www.wiley-vch.de/contents/jc_2002/2008/z703813_s.pdf or from author. Please note:...
Objectives: To identify the staphylococcal cassette chromosome mec (SCCmec) types of methicillin-resistant Staphylococcus aureus (MRSA) isolated from bovine milk, and examine genetic relatedness between MRSA milk human isolates.
Severe fever with thrombocytopenia syndrome (SFTS) is an emerging infectious disease that was recently identified in China, South Korea and Japan. The objective of the study to evaluate epidemiologic clinical characteristics SFTS Korea.SFTS a reportable Korea. We included all cases reported Centers for Disease Control Prevention (KCDC) from January 2013 December 2015. Clinical information gathered by reviewing medical records, were analyzed using both KCDC surveillance data patient records....
Background: From May to July 2015, the Republic of Korea experienced largest outbreak Middle East respiratory syndrome (MERS) outside Arabian Peninsula.A total 186 patients, including 36 deaths, had been diagnosed with MERS-coronavirus (MERS-CoV) infection as September 30th, 2015.Materials and Methods: We obtained information patients who were confirmed have MERS-CoV infection.MERS-CoV was using real-time reverse-transcriptase polymerase chain reaction assay. Results:The median age 55 years...
Abstract In native tissues, cellular and acellular components are anisotropically organized often aligned in specific directions, providing structural mechanical properties for actuating biological functions. Thus, engineering alignment not only allows emulation of tissue structures but might also enable implementation functionalities. However, achieving desired is challenging, especially three-dimensional constructs. By exploiting the elastomeric property polydimethylsiloxane...
This nationwide, prospective cohort study evaluated pulmonary function and radiological sequelae according to infection severity in 73 survivors from the 2015 Middle East respiratory syndrome (MERS) outbreak Korea.Patients with severe pneumonia MERS-coronavirus had more impaired than those no or mild at 1-year follow-up, which was compatible sequelae.Severe significantly impairs makes long MERS.
Journal Article Three-dimensional intestinal villi epithelium enhances protection of human cells from bacterial infection by inducing mucin expression Get access Si Hyun Kim, Kim Department Chemical Engineering, Hongik University, Seoul Korea Search for other works this author on: Oxford Academic Google Scholar Meiying Chi, Chi Chemistry and Nano Sciences (BK21 plus), Global Top 5 Program, Ewha Womans Seoul, Banya Yi, Yi So Seunghan Oh, Oh Younghoon BK21 Plus Graduate Animal Science...