Cutaneous wound healing is a biological process that occurs upon skin injury and involves different mechanisms to repair tissue damage. Improper or prolonged curation period of lesions may induce unpleasant complications. Cold atmospheric microwave plasma (CAMP) an upcoming medical therapeutic option for infection treatment. However, the molecular CAMP-mediated canine are not well characterized. Wound-healing activity was examined elucidate effects CAMP. Canine keratinocytes (CPEKs) were...

Abstract Background Canine atopic dermatitis (cAD) varies in prevalence and lesion distribution across breeds. In contrast to Western countries, many Asian countries favour small‐to‐medium dog However, previous studies have focused primarily on medium‐to‐large Objectives To analyse the of cAD common breeds Korea, focusing breed‐specific characteristics. Animals Nine (<25 kg body weight) were selected from 331 client‐owned dogs with cAD, representing 77% total group. Materials Methods...

Blood, saliva, and nail samples were collected from 54 dogs 151 cats analyzed for the presence of Bartonella henselae with a novel nested polymerase chain reaction (PCR) method.Bartonella (B.) was detected in feral cat blood (41.8%), saliva (44.1%), (42.7%) samples.B. also pet (33.3%), (43.5%), (29.5%) dog (16.6%), (18.5%), (29.6%) samples.Nine infected B. clarridgeiae 2 co-infected dogs.This report is first to investigate prevalence Korea, suggests that may serve as potential reservoirs.

Enterococci are major zoonotic bacteria that cause opportunistic infections in human beings and animals. Moreover, pathogenic strains can be disseminated between animals, particularly companion animals come into frequent contact with people. Recently, Enterococcus faecium clonal complex 17 (CC17) has emerged as a pandemic clone. Most CC17 ampicillin resistant possess virulence genes such esp hyl. Despite the possible dissemination of prevalence data about is limited. In present study,...

Gnotobiotic piglets (n = 10) were hand-reared in conventional germ-free facilities.Piglet body temperatures measured with rectal and non-contact infrared thermometry (NIFT) on the lower eyelid, auricular center margin, parietal regions, axilla, central abdomen dorsum, perianal region.Body temperature measurements at abdomen, cranial regions had NIFT values which a significant linear relationship (p<0.0001) thermometry.The predicted equations of between-subject formulas calculated as follows:...

Topical or oral azole antifungals are commonly used in canine atopic dermatitis (AD), as the lipophilic yeast Malassezia pachydermatis exacerbates AD. To examine whether AD lesions harbor azole-resistant M. isolates East Asia, we investigated vitro susceptibility of to ketoconazole (KTZ) and itraconazole (ITZ) obtained from canines Japan, Korea Taiwan. The minimum inhibitory concentrations (MICs) KTZ ITZ were measured by E-test using Sabouraud dextrose agar with 0.5% Tween 40. MICs for...

Background Pseudomonas aeruginosa is a challenging pathogen cultured from cases of acute and chronic canine otitis sometimes in deep pyoderma. The spread antimicrobial resistance, especially carbapenem serious therapeutic challenge worldwide. Hypothesis/Objectives To investigate the identification characterization resistant P. clinical isolates. Materials Clinical isolates (n = 80) were collected dogs with pyoderma 18) 62) Korea. Methods Antimicrobial susceptibility was determined using agar...

Abstract Carbapenems are broad-spectrum antibiotics widely used for the treatment of human infections caused by multidrug-resistant (MDR) Gram-negative bacteria. However, emerging carbapenemase-producing Enterobacterales (CPE) rising as a public threat to and animal health. We screened clinical bacterial isolates from 241 dogs 18 cats hospitalized at Veterinary Medical Teaching Hospital, Seoul National University, 2018 2020 carbapenemase production. In our study, 5 strains...

Discovery of Helicobacter (H.) pylori has led to a fundamental change in our understanding gastric diseases humans. Previous studies have found various spp. dogs and cats, pets been questioned as zoonotic carrier. The present study surveyed the infections investigated presence H. felis domestic feral cats Korea. Sixty-four 101 were selected from an animal shelter. Saliva feces evaluated by genus-specific polymerase chain reaction (PCR). Genus-specific PCR positive samples further for using...

Staphylococcus pseudintermedius is a common pathogen of skin and ear infections in dogs. The widespread rapid emergence meticillin-resistant S. (MRSP) has created therapeutic challenges veterinary medicine the need for alternative treatments.We aimed to evaluate vitro antimicrobial activity essential oil manuka (Leptospermum scoparium) against pseudintermedius.This study was performed using strains isolated from dogs with collected throughout Korea between 2009 2011. 39 MRSP 11...

In humans, skin barrier dysfunction is thought to be responsible for enhanced penetration of allergens.Similar conditions seen in canine atopic dermatitis (CAD) characterized by derangement corneocytes and disorganization intercellular lipids the stratum corenum (SC) with decreased ceramide levels.This study was designed evaluate effects a moisturizer containing on dogs CAD.Dogs (n = 20, 3∼8 years old) mild moderate clinical signs were recruited applied 4 weeks.Transepidermal water loss...

Abstract Hair loss or alopecia is an unpleasant symptom that exacerbates individual's self-esteem and requires appropriate treatment. The Wnt/β-catenin signaling a central pathway promotes dermal papilla induction keratinocyte proliferation during hair follicle renewal. GSK-3β inactivated by its upstream Akt ubiquitin-specific protease 47 (USP47) has been shown to inhibit β-catenin degradation. cold atmospheric microwave plasma (CAMP) energy enriched with mixtures of radicals. CAMP reported...

Helicobacter spp. may have multiple routes of transmission. It is unclear, however, whether the agent zoonotic and therefore transmitted from an animal reservoir, including dogs. The aim this population-based study was to assess relationship between pet ownership or frequent exposure dogs infection, especially focusing on HHLO-2 (Helicobacter heilmannii-like organisms type 2) in saliva feces samples Korea, using non-invasive genus/species-specific PCR. One hundred twenty-four eligible human...

The purpose of this study was to evaluate the effects a topical spray containing 0.0584% hydrocortisone aceponate (HCA) on canine atopic dermatitis (CAD) and skin barrier function during treatment CAD.Twenty-one dogs that fulfilled diagnostic criteria for CAD were included in study.The HCA applied once day lesions all 7 or 14 days.Clinical assessment performed before (day 0) after 14), clinical responses correlated with changes function.CAD severity significantly decreased days based lesion...

The increasing prevalence of antimicrobial resistance among bacteria in dogs with otitis externa has led to a need for novel therapeutic agents.To examine the antibacterial effects manuka oil combined ethylenediaminetetraacetic acid-tromethamine (Tris-EDTA) against Gram-negative isolates from externa.A total 53 clinical including Pseudomonas aeruginosa, Escherichia coli, Klebsiella pneumoniae ssp. and Proteus mirabilis. Antimicrobial susceptibility was determined using disk diffusion;...

Hair cycle arrest (HCA) is a noninflammatory alopecic disease affecting various dog breeds, particularly Pomeranian dogs. This probably hereditary disorder considering the strong breed predisposition. Despite efforts to identify pathogenesis of this disease, an underlying specific cause unknown.To candidate gene mutations for HCA in dogs.Four dogs diagnosed with and four unaffected dogs.Whole blood was used DNA extraction. Whole-genome sequencing (WGS) performed, variants were analysed using...

Cold atmospheric plasma is a novel innovative approach for wound care, and it currently underrepresented in veterinary medicine.To investigate the efficacy safety of using cold microwave (CAMP) as an adjunct therapy healing dogs cats.Wound outcomes were retrospectively analyzed clinical records client-owned cats who first managed through standard care alone (pre-CAMP period) subsequently via CAMP (CAMP period). The degree was estimated based on size modified scoring system.Of 27 acute...

A seven-year-old castrated male Yorkshire terrier dog was presented for a recurrent skin disease.Erythematous during the first visit progressed from multiple plaques to patch lesions and exudative erosion in oral mucosa membrane.Biopsy samples were taken erythematous diagnosed with epitheliotropic T cell cutaneous lymphoma by histopathology immunochemical stain.In serum chemistry, had hypercalcemia (15.7 mg/dl) mild increased alkaline phosphatase (417 U/l).Immunohistochemistry performed...

The hypoglycemic effects after oral administration of vanadium have been studied previously in many species such as rats, mice and even humans.However, there has no prior report on the glucose lowering effect diabetic dogs.Therefore, purpose this study was to evaluate dogs.Diabetes mellitus dogs induced by alloxan monohydrate intravenous injection.The were divided into two groups, one control (DC) group (n = 4) other treated (DV) 6).Fresh water supplied DC group, but sodium metavanadate...

Enterococcus pRE25 is a conjugative and mobilising multiresistance plasmid from faecalis RE25. pRE25-like enterococcal pWZ909 mediates the delivery of vancomycin resistance to methicillin-resistant Staphylococcus aureus via Tn1546-like transposon. However, whether elements contribute multidrug in spp. has not yet been investigated. Here we describe first detection chromosomal DNA multidrug-resistant pseudintermedius (MDRSP). A total 46 MDRSP clinical strains were isolated canine pyoderma...

Osteosarcoma is known to be one of the frequently occurring cancers in dogs. Its prognosis usually very poor, with a high incidence lung metastasis. Although radiation therapy has become major therapeutic choice for canine osteosarcoma, costs and unexpected side effects prevent some patients from considering this treatment. Cold atmospheric plasma (CAP) an ionized gas energy at low temperatures, it produces reactive oxygen species that mediate many signaling pathways. researchers have used...

To evaluate clinical effects of autogenous toxoid-bacterin treatment for Staphylococcus aureus subclinical mastitis in lactating cows, 22 cows which had at least one S. infected quarter were selected from among a prevalent dairy farm. Eleven injected with their own and the others maintained as non-injected control. In group, 27% quarters cured during 12-week trial, compared to 5% control group. New intramammary infections only detected 3 Mean IgG antibody titer against somatic antigens...

Background Mupirocin is a topical antibacterial drug used for the treatment of staphylococcal infections, including meticillin‐resistant Staphylococcus pseudintermedius (MRSP). The recent emergence resistance to mupirocin major concern in many countries. Objectives This study investigated prevalence and genotype mupirocin‐resistant S. isolated from pet dogs with pyoderma. Samples A total 110 clinical isolates were collected pyoderma ( n = 110) between July 2010 September 2016. All animals...