A5061204327- Scoliosis diagnosis and treatment
- Spinal Fractures and Fixation Techniques
- Spine and Intervertebral Disc Pathology
- Cervical and Thoracic Myelopathy
- Medical Imaging and Analysis
- Pelvic and Acetabular Injuries
- Musculoskeletal pain and rehabilitation
- Spinal Hematomas and Complications
- Frailty in Older Adults
- Cardiac, Anesthesia and Surgical Outcomes
- Parkinson's Disease and Spinal Disorders
- Hip and Femur Fractures
- Health Systems, Economic Evaluations, Quality of Life
- Hip disorders and treatments
- Glioma Diagnosis and Treatment
- Anesthesia and Pain Management
- Nutrition and Health in Aging
- Orthopaedic implants and arthroplasty
- Machine Learning in Materials Science
- Colorectal Cancer Surgical Treatments
- Management of metastatic bone disease
- Blood transfusion and management
- Meningioma and schwannoma management
- Intraoperative Neuromonitoring and Anesthetic Effects
- Infectious Diseases and Tuberculosis
University of Virginia Health System
2016-2025
Neurological Surgery
2016-2025
University of Virginia Medical Center
2016-2025
University of Virginia
2016-2025
University of Rochester
2024
Hospital for Special Surgery
2010-2023
University of California, San Francisco
2011-2023
Twin Cities Spine Center
2009-2023
Toronto Western Hospital
2023
Brown University
2000-2023
Purpose The prognostic role of extent resection (EOR) low-grade gliomas (LGGs) is a major controversy. We designed retrospective study to assess the influence EOR on long-term outcomes LGGs. Patients and Methods population (N = 216) included adults undergoing initial hemispheric LGG. Region-of-interest analysis was performed measure tumor volumes based fluid-attenuated inversion-recovery (FLAIR) imaging. Results Median preoperative postoperative were 36.6 cm 3 (range, 0.7 246.1 ), 3.7 0...
In Brief Study Design. Prospective multicenter study evaluating operative (OP) versus nonoperative (NONOP) treatment for adult spinal deformity (ASD). Objective. Evaluate correlations between spinopelvic parameters and health-related quality of life (HRQOL) scores in patients with ASD. Summary Background Data. Sagittal is commonly defined by an increased sagittal vertical axis (SVA); however, SVA alone may underestimate the severity deformity. Spinopelvic provide a more complete assessment...
Positive spinal regional and global sagittal malalignment has been repeatedly shown to correlate with pain disability in thoracolumbar fusion.To evaluate the relationship between cervical alignment postoperative outcomes for patients receiving multilevel posterior fusion.From 2006 2010, 113 received fusion stenosis, myelopathy, kyphosis. Radiographic measurements made at intermediate follow-up included following: (1) C1-C2 lordosis, (2) C2-C7 (3) vertical axis (C2-C7 SVA; distance C2 plumb...
Positive spinal regional and global sagittal malalignment has been repeatedly shown to correlate with pain disability in thoracolumbar fusion.To evaluate the relationship between cervical alignment postoperative outcomes for patients receiving multilevel posterior fusion.From 2006 2010, 113 received fusion stenosis, myelopathy, kyphosis. Radiographic measurements made at intermediate follow-up included following: (1) C1-C2 lordosis, (2) C2-C7 (3) vertical axis (C2-C7 SVA; distance C2 plumb...
Background: Cervical spondylotic myelopathy is the leading cause of spinal cord dysfunction worldwide. The objective this study was to evaluate impact surgical decompression on functional, quality-of-life, and disability outcomes at one year after surgery in a large cohort patients with condition. Methods: Adult symptomatic cervical magnetic resonance imaging evidence compression were enrolled twelve North American centers from 2005 2007. At enrollment, categorized as mild (modified Japanese...
BACKGROUND: Global sagittal malalignment is significantly correlated with health-related quality-of-life scores in the setting of spinal deformity. In order to address rigid deformity patterns, use osteotomies has seen a substantial increase. Unfortunately, variations established techniques and hybrid combinations have made comparisons outcomes difficult. OBJECTIVE: To propose classification system anatomically-based provide common language among spine specialists. METHODS: The proposed...
BACKGROUND: The SRS-Schwab classification of adult spinal deformity (ASD) is a validated system that provides common language for the complex pathology ASD. Classification reliability has been reported; however, correlation with treatment not assessed. OBJECTIVE: To assess clinical relevance based on correlations health-related quality life (HRQOL) measures and decision to pursue operative vs nonoperative treatment. METHODS: Prospective analysis consecutive ASD patients (18 years age older)...
Retrospective review of prospective, multicenter database.The aim the study was to determine age-specific spino-pelvic parameters, extrapolate Oswestry Disability Index (ODI) values from published Short Form (SF)-36 Physical Component Score (PCS) data, and propose realignment thresholds for adult spinal deformity (ASD).The Scoliosis Research Society-Schwab classification offers a framework defining alignment in patients with ASD. Although changes patient-reported outcomes have been...
In Brief Study Design. Retrospective review of a prospectively collected database. Objective. Our objective was to assess the rates postoperative wound infection associated with spine surgery. Summary Background Data. Although after surgery remains common source morbidity, estimates its occurrence remain relatively limited. The Scoliosis Research Society collects morbidity and mortality data from members, including infection. Methods. database queried for all reported cases 2004 2007. Cases...
Retrospective review of a multicenter database.To determine the complication rates associated with surgical treatment pediatric scoliosis and to assess variables increased rates.Wide variability is reported for complications operative scoliosis. Limited number patients, surgeons, diagnoses occur in most reports. The Scoliosis Research Society Morbidity Mortality (M&M) database aggregates deidentified data, permitting determination from large numbers patients surgeons.Cases (age ≤18 years),...
Background: Adult spinal deformity is a prevalent cause of pain and disability. Established measures sagittal spinopelvic alignment such as vertical axis pelvic tilt can be modified by postural compensation, including retroversion, knee flexion, the use assistive devices for standing. We introduce T1 angle, novel measure that simultaneously accounts both inclination retroversion. The purpose this study was to investigate relationship angle other established correlate these parameters with...
In Brief Study Design. Retrospective review of a prospective, multicenter database. Objective. The purpose this study was to assess whether elderly patients undergoing scoliosis surgery had an incidence complications and improvement in outcome measures comparable with younger patients. Summary Background Data. Complications increase age for adults surgery, but impacts the outcomes older is largely unknown. Methods. This retrospective spinal deformity Patients complete Oswestry Disability...
OBJECTIVE Although multiple reports have documented significant benefit from surgical treatment of adult spinal deformity (ASD), these procedures can high complication rates. Previously reported complications rates associated with ASD surgery are limited by retrospective design, single-surgeon or single-center cohorts, lack rigorous data on complications, and/or follow-up. Accurate definition is important and may serve as a resource for patient counseling efforts to improve the safety care....
In Brief Study Design. Multicenter, prospective, consecutive series. Objective. To evaluate responsiveness of the Scoliosis Research Society (SRS)-Schwab adult spinal deformity (ASD) classification to changes in health-related quality life (HRQOL) after treatment for ASD. Summary Background Data. Ideally, a system should describe and be responsive disease state. We hypothesized that SRS-Schwab is HRQOL measures Methods. A multicenter, series from International Spine Group. Inclusion...
Low-grade gliomas (LGGs) frequently infiltrate highly functional or "eloquent" brain areas. Given the lack of long-term survival data, prognostic significance eloquent tumor location and role mapping during resective surgery in presumed regions are unknown.We performed a retrospective analysis 281 cases involving adults who underwent resection supratentorial LGG at referral center. Preoperative MR images were evaluated blindly for involvement areas, including sensorimotor language cortices,...
Retrospective review of a prospectively collected, multicenter database.To assess rates new neurologic deficit (NND) associated with spine surgery.NND is potential complication surgery, but previously reported are often limited by small sample size and single-surgeon experiences.The Scoliosis Research Society morbidity mortality database was queried for spinal surgery cases complicated NND from 2004 to 2007, including nerve root (NRD), cauda equina (CED), cord (SCD). Use neuromonitoring...
A retrospective analysis of a prospective, multicenter database.The aim this study was to evaluate the health impact symptomatic adult spinal deformity (SASD) by comparing Standard Form Version 2 (SF-36) scores for SASD with United States normative and chronic disease values.Recent data have identified radiographic parameters correlating poor health-related quality life SASD. Disability comparisons between patients diseases may provide further insight burden caused SASD.Consecutive patients,...
Despite the complexity of cervical spine deformity (CSD) and its significant impact on patient quality life, there exists no comprehensive classification system. The objective this study was to develop a novel system based modified Delphi approach characterize intra- interobserver reliability classification.Based an extensive literature review with expert panel, CSD generated. included descriptor 5 modifiers that incorporated sagittal, regional, global spinopelvic alignment neurological...
Improved understanding of rod fracture (RF) in adult spinal deformity could be valuable for implant design, surgical planning, and patient counseling.To evaluate symptomatic RF after posterior instrumented fusion deformity.A multicenter, retrospective review was performed. Inclusion criteria were deformity, age older than 18 years, more 5 levels fusion. Rod failures divided into early (≤12 months) late (>12 months).Of 442 patients, 6.8% had RF. rates 8.6% titanium alloy, 7.4% stainless...
Rates of complications associated with the surgical treatment cervical spondylotic myelopathy (CSM) are not clear. Appreciating these risks is important for patient counseling and quality improvement. The authors sought to assess rates risk factors perioperative delayed CSM.Data from AOSpine North America Cervical Spondylotic Myelopathy Study, a prospective, multicenter study, were analyzed. Outcomes data, including adverse events, collected in standardized manner externally monitored....
Improved understanding of rod fracture (RF) following adult spinal deformity (ASD) surgery could prove valuable for surgical planning, patient counseling, and implant design. The objective this study was to prospectively assess the rates risk factors RF ASD.This a prospective, multicenter, consecutive series. Inclusion criteria were ASD, age > 18 years, ≥5 levels posterior instrumented fusion, baseline full-length standing spine radiographs, either development or radiographs obtained at...