A5055891687- Coronary Interventions and Diagnostics
- Vascular Procedures and Complications
- Acute Myocardial Infarction Research
- Cardiac Imaging and Diagnostics
- Antiplatelet Therapy and Cardiovascular Diseases
- Venous Thromboembolism Diagnosis and Management
- Peripheral Artery Disease Management
- Cardiovascular Function and Risk Factors
- Heart Failure Treatment and Management
- Blood Pressure and Hypertension Studies
- Cardiovascular Health and Disease Prevention
- Cardiac Valve Diseases and Treatments
- Central Venous Catheters and Hemodialysis
- Cardiovascular Disease and Adiposity
- Cardiac, Anesthesia and Surgical Outcomes
- Lipoproteins and Cardiovascular Health
- Cardiac electrophysiology and arrhythmias
- Medication Adherence and Compliance
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Aortic aneurysm repair treatments
- Diagnosis and Treatment of Venous Diseases
- Cerebrovascular and Carotid Artery Diseases
- Advanced MRI Techniques and Applications
- Atrial Fibrillation Management and Outcomes
- Cardiac Arrest and Resuscitation
Yonsei University
2016-2025
Wonju Severance Christian Hospital
2015-2025
Severance Hospital
2024
Pusan National University Hospital
2015
Recent studies suggest that the intracoronary administration of bone marrow (BM)-derived mesenchymal stem cells (MSCs) may improve left ventricular function in patients with acute myocardial infarction (AMI).However, there is still argumentative for safety and efficacy MSCs AMI setting.We thus performed a randomized pilot study to investigate AMI.Eighty after successful reperfusion therapy were randomly assigned received an autologous BM-derived into infarct related artery at 1 month.During...
Background In clinical practice, a risk prediction model is an effective solitary program to predict prognosis in particular patient groups. B-type natriuretic peptide (BNP)and N-terminal pro-b-type (NT-proBNP) are widely recognized outcome-predicting factors for patients with heart failure (HF).This study derived external validation of score 1-year mortality after discharge hospitalized HF using the Meta-analysis Global Group Chronic Heart Failure (MAGGIC)program data. We also assessed...
Background: There is a paucity of data on the effects adherence to treatment outcomes for patients with acute heart failure (HF) in Korea. We used HF performance measures evaluate overall and whether this affects clinical outcomes. Methods Results: Among 3,466 Korean Heart Failure Registry, 1,527 left ventricular systolic dysfunction (LVSD) who survived hospitalization were evaluated. Modified validated defined as follows: use at discharge angiotensin-converting enzyme inhibitor (ACEI),...
B-type natriuretic peptide (BNP) has prognostic significance in heart failure (HF), and reductions BNP may predict clinical improvement. However, there are limited data regarding the value of during short-term follow-up. The aim this study was to evaluate relationship between follow-up mortality after discharge patients with HF. We analyzed 427 hospitalized HF from Wonju Severance Christian Hospital Heart Failure Registry April 2011 December 2013, a planned period through February 2016. Of...
While distal radial artery (DRA) access is increasingly being used for diagnostic coronary angiography, limited information available regarding DRA size. We aimed to determine the reference diameters of Korean patients and identify predictors diameter < 2.3 mm.
Carotid intima-media thickness (CIMT) is considered as a surrogate marker for cardiovascular disease (CVD).We determined the normative value of CIMT and correlates CVD risk factors Framingham score (FRS) in Korean rural middle-aged population.We measured with B-mode ultrasonography 1,759 subjects, aged 40 to 70 yr, population-based cohort Korea.A healthy reference sample (n = 433) without CVD, normal weight metabolic parameters was selected establish values.Correlates between conventional...
Abstract Background: Studies investigating the clinical outcome of intravascular ultrasound (IVUS)‐guided primary percutaneous coronary intervention (PPCI) in patients with ST‐segment elevation myocardial infarction (STEMI) show conflicting results. The aim our study was to evaluate whether IVUS‐guidedPPCI drug‐eluting stents (DESs) STEMI improves outcome. Hypothesis: IVUS‐guided PPCI is superior angio‐guided PPCI. Methods: Three hundred forty‐one who underwent for and survived...
Obesity is often associated with better clinical outcomes in heart failure (HF). This so-called obesity paradox remains controversial. The aim of present study was to investigate the prognostic value patients hospitalized for systolic HF.We performed a pooled analysis data from two multicenter, observational HF studies. Patients were eligible study. We divided subjects into groups, normal body mass index (BMI) group and high BMI group. Study endpoints included all-cause mortality any...
Stress-induced cardiomyopathy (SCM) is characterized by a transient left ventricular (LV) dysfunction due to emotional and physical stress. There are limited data about the clinical characteristics in Korean patients. We sought clarify features prognosis patients with SCM.We reviewed 39 cases diagnosed SCM tertiary hospital. The was as: 1) no previous history of cardiac disease, 2) acute onset, 3) regional wall motion abnormality, typically takotsubo or inverted shape echocardiography, 4)...
Although metabolic syndrome (MetS) is associated with increased cardiovascular mortality and the development of atherosclerosis, consensus still lacking on status function geometry in MetS patients.We investigated relation between left ventricle (LV) function, carotid intima-media thickness (IMT) arterial stiffness a community-based cohort 702 adult subjects.Subjects were categorized into three groups according to number components present, as defined by Adult Treatment Panel Ш guidelines:...
Background/Aims: Newer P2Y12 inhibitors, such as prasugrel and ticagrelor, have greater antiplatelet efficacy but may increase the risk of bleeding. In this study, we compared pharmacodynamic ticagrelor in East Asian patients with acute coronary syndrome (ACS). Methods: We selected 83 ACS undergoing percutaneous intervention who were discharged 90 mg twice daily (n = 24), 10 39) or 5 20). After 2 to 4 weeks, on-treatment platelet reactivity (OPR) was assessed terms reaction units (PRUs)...
Purpose:We aimed to investigate whether combination therapy using intracoronary (IC) abciximab and aspiration thrombectomy (AT) enhances myocardial perfusion compared each treatment alone in patients with ST-elevation infarction (STEMI) undergoing primary percutaneous coronary intervention (PCI).Materials Methods: We enrolled 40 STEMI, who presented within 6 h of symptom onset had Thrombolysis MI flow 0/1 or a large angiographic thrombus burden (grade 3/4).Patients were randomly divided into...
Cardiac remodeling characterized by cardiac fibrosis is a pathologic process occurring after acute myocardial infarction. Fibrosis can be ameliorated interferon-gamma (IFN-γ), which soluble cytokine showing various effects such as anti-fibrosis, apoptosis, anti-proliferation, immunomodulation, and anti-viral activities. However, the role of IFN-γ in myofibroblasts not well established. Therefore, we investigated anti-fibrotic human (hCMs) vitro whether indoleamine 2,3-dioxygenase (IDO),...
BackgroundElevated B-type natriuretic peptide (BNP) levels in patients hospitalized for acute myocardial infarction (AMI) are associated with heart failure and mortality. However, the role of BNP after hospital discharge is not clear. Therefore, we assessed relationship between short-term follow-up clinical outcomes including all-cause mortality major adverse cardiovascular events (MACE) AMI discharge.MethodsFrom a prospective single-center percutaneous coronary intervention (PCI) registry,...
Atypical chest pain and diabetic autonomic neuropathy attract less clinical attention, leading to underdiagnosis delayed treatment. To evaluate the long-term impact of atypical diabetes mellitus (DM), we categorized 11,159 patients with acute myocardial infarction (AMI) from Korea AMI-National Institutes Health between November 2011 December 2015 into four groups (atypical DM, non-DM, typical non-DM). The primary endpoint was defined as patient-oriented composite (POCE) at 2 years including...