A5087393043- Nanoplatforms for cancer theranostics
- Total Knee Arthroplasty Outcomes
- Orthopaedic implants and arthroplasty
- Orthopedic Infections and Treatments
- Advanced Nanomaterials in Catalysis
- Bacterial biofilms and quorum sensing
- Inflammasome and immune disorders
- Wound Healing and Treatments
- Diabetic Foot Ulcer Assessment and Management
- Legionella and Acanthamoeba research
- Advanced Glycation End Products research
University of Science and Technology of China
2021-2024
Anhui Medical University
2021
Abstract Oxidative stress, chronic inflammation, and immune senescence are important pathologic factors in diabetic wound nonhealing. This study loads taurine (Tau) into cerium dioxide (CeO 2 ) to develop CeO @Tau nanoparticles with excellent antioxidant, anti‐inflammatory, anti‐aging properties. To enhance the drug penetration efficiency wounds, is encapsulated gelatin methacryloyl (GelMA) hydrogel prepare @Tau@Hydrogel@Microneedle (CTH@MN) patch system. Microneedle technology achieves...
There is an increasingly growing demand to balance tissue repair guidance and opportunistic infection (OI) inhibition in clinical implant surgery. Herein, we developed a nanoadjuvant for all-stage biofilm-responsive OI eradication via situ incorporating Cobaltiprotoporphyrin (CoPP) into Prussian blue (PB) prepare PB-CoPP nanozymes (PCZs). Released CoPP possesses pro-efferocytosis effect eliminating apoptotic progressing necrotic cells trauma, thus preventing secondary inflammation. Once OIs...
Bone cement spacers are widely used in two-stage revision surgeries for periprosthetic joint infection (PJI) after total knee arthroplasty. Current spacer design results insufficient release of drugs; therefore, current have low efficacy. In this study, we explored a set alternative articular using 3D printing technology. This novel will increase effectiveness surgery PJI.The was designed CAD software and constructed on site 3D-printed silicone mold during debridement surgery. We carried out...
Objective Total hip arthroplasty (THA) combined with proximal femoral reconstruction is a novel osteotomy technique developed to address severe deformities. There paucity of robust clinical and radiological evidence regarding the outcomes this technique. This study aimed evaluate THA during early follow‐up. Methods retrospective case series 63 hips who underwent at single institution between January 2020 July 2023. The mean age patients was 39.6 ± 12.6 years. follow‐up 25.6 3.8 months....