A5017240012- Autoimmune and Inflammatory Disorders Research
- Chemical and Physical Properties in Aqueous Solutions
- Rheumatoid Arthritis Research and Therapies
- Water Quality Monitoring Technologies
- Advanced biosensing and bioanalysis techniques
- Crystallization and Solubility Studies
- Water Quality and Pollution Assessment
- Microfluidic and Capillary Electrophoresis Applications
- Bacteriophages and microbial interactions
- Biosensors and Analytical Detection
- Protein purification and stability
- Adolescent and Pediatric Healthcare
- Microfluidic and Bio-sensing Technologies
- Water Quality Monitoring and Analysis
- Extraction and Separation Processes
- Fungal and yeast genetics research
- Geochemistry and Geologic Mapping
- Advanced Biosensing Techniques and Applications
- Environmental Toxicology and Ecotoxicology
- Algal biology and biofuel production
- Musculoskeletal Disorders and Rehabilitation
- Health Systems, Economic Evaluations, Quality of Life
- Innovation, Technology, and Society
- SARS-CoV-2 detection and testing
- Pesticide and Herbicide Environmental Studies
Universidade Católica Portuguesa
2020-2021
Institute for Biotechnology and Bioengineering
2011-2020
University of Lisbon
2015-2020
University of Houston
2018
Lateral flow assays (LFAs) are a widely-used point-of care diagnostic format, but suffer from limited analytical sensitivity, especially when read by eye. It has recently been reported that LFA performance can be improved using magnetic reporter particles and an external field applied at the test line. The mechanism of sensitivity/performance enhancement was suggested to concentration/retardation Here we demonstrate additional particle relocation where lower depths translucent strip relocate...
Alachlor has been a commonly applied herbicide and is substance of ecotoxicological concern. The present study aims to identify molecular biomarkers in the eukaryotic model Saccharomyces cerevisiae that can be used predict potential cytotoxic effects alachlor, while providing new mechanistic clues with possible relevance for experimentally less accessible eukaryotes. It focuses on genome-wide expression profiling yeast population response two exposure scenarios exerting from slight moderate...
Seroprevalence studies are crucial both for estimating the prevalence of SARS-CoV-2 exposure and to provide a measure efficiency confinement measures. Portuguese universities were closed on March 16th 2020, when Portugal only registered 62 infection cases per million. We have validated ELISA assay stabilized full-length spike protein using 216 pre-pandemic 19 molecularly diagnosed positive individual's samples. At NOVA University Lisbon, presential work was partially resumed May 25th with...
Until recently, innovation in healthcare was mainly achieved through the development of new drugs, therapies, and medical devices by big pharma medtech companies; however, innovative potential for this field is much broader. The patients caregivers' role often associated with disease management, demand their own illness data, its exchange other patients. However, capacity to innovate cope limitations health condition a growing phenomenon starting be supported stakeholders achieve truly...
The N-terminal proline-rich domain (Zera®) of the maize storage protein γ-zein is a self-assembling produced and patented by EraBiotech, which can be fused with proteins interest. Aqueous two-phase system (ATPS) biocompatible method for purification, without denaturation or loss biological activity due to high water content, low interfacial tension stabilizing effect polymers. This work aims at developing optimizing scalable process extraction Zera® fusion model proteins, Zera®, Zera®-alpha...
<sec> <title>UNSTRUCTURED</title> Although innovation in healthcare is still mainly seen with the emergence of new drugs, therapies, and medical devices by big pharma MedTech companies, society continues to face concerns unmet health needs that only users their daily life. Our previous research has shown develop novel solutions, from simple adaptations products highly technological biomedical devices, these innovations significantly improve quality In this paper, we analyzed solutions...