- Biosensors and Analytical Detection
- Microfluidic and Capillary Electrophoresis Applications
- Advanced biosensing and bioanalysis techniques
- Innovative Microfluidic and Catalytic Techniques Innovation
- Mycotoxins in Agriculture and Food
- Microfluidic and Bio-sensing Technologies
- SARS-CoV-2 detection and testing
- Chemical and Physical Properties in Aqueous Solutions
- Listeria monocytogenes in Food Safety
- Protein purification and stability
- Indoor Air Quality and Microbial Exposure
- Monoclonal and Polyclonal Antibodies Research
- Advanced Biosensing Techniques and Applications
- Bacteriophages and microbial interactions
- Viral Infectious Diseases and Gene Expression in Insects
- Infection Control and Ventilation
- Crystallization and Solubility Studies
- COVID-19 epidemiological studies
- COVID-19 and healthcare impacts
- Pancreatic function and diabetes
- Electrowetting and Microfluidic Technologies
- Analytical Chemistry and Sensors
- Advanced Proteomics Techniques and Applications
- Plant Pathogens and Resistance
- Probiotics and Fermented Foods
Stockholm University
2020-2024
Science for Life Laboratory
2020-2023
KTH Royal Institute of Technology
2020-2022
Instituto de Engenharia de Sistemas e Computadores Microsistemas e Nanotecnologias
2014-2021
Institute for Biotechnology and Bioengineering
2014-2021
University of Lisbon
2014-2021
Instituto Superior Técnico
2015-2018
University of Vassouras
2018
Instituto de Engenharia de Sistemas e Computadores Investigação e Desenvolvimento
2015
Instituto Politécnico de Lisboa
2014
LAMP-based platform for SARS-CoV-2 RNA detection incorporating beads to remove primer-dimers, enhance fluorescent signal and stop the reaction after amplification.
ConspectusThe development of robust methods allowing the precise detection specific nucleic acid sequences is major societal relevance, paving way for significant advances in biotechnology and biomedical engineering. These range from a better understanding human disease at molecular level, discovery novel biopharmaceuticals vaccines, to improvement biotechnological processes providing improved food quality safety, efficient green fuels, smart textiles. Among these applications, significance...
Abstract Microfluidics has emerged rapidly over the past 20 years and been investigated for a variety of applications from life sciences to environmental monitoring. Although continuous-flow microfluidics is ubiquitous, segmented-flow or droplet offers several attractive features. Droplets can be independently manipulated analyzed with very high throughput. Typically, carried out within planar networks microchannels, namely, microfluidic chips. We propose that fibers offer an interesting...
Immunoassays are fast and sensitive techniques for analyte quantification, their use in point-of-care devices medical, environmental, food safety applications has potential benefits of cost, portability, multiplexing. However, immunoassays often affected by matrix interference effects, requiring the complex laboratory extraction concentration procedures order to achieve required sensitivity. In this paper we propose an integrated microfluidic device simultaneous clean-up, detection. This...
Since the COVID-19 outbreak was declared a pandemic by World Health Organization (WHO) in March 2020, ongoing efforts have been made to develop sensitive diagnostic platforms. Detection of viral RNA provides highest sensitivity and specificity for detection early asymptomatic infections. Thus, this work aimed at developing label-free genosensor composed graphene as working electrode that could be embedded into flex printed circuit board (FPCB) rapid, sensitive, amplification-free SARS-CoV-2....
Portable, rapid, cost effective and simple analytical tools are in increasing demand to facilitate the routine monitoring of target chemical/biological compounds at point-of-need. Such devices highly relevant within context food safety, particularly concerning screening toxic strictly regulated mycotoxins. To achieve ultrarapid detection mycotoxins, namely aflatoxin B1, ochratoxin A deoxynivalenol, point-of-need, a novel multiplexed bead-based microfluidic competitive immunosensor, coupled...
As the third wave of COVID-19 pandemic hit Portugal, it forced country to reintroduce lockdown measures due hospitals reaching their full capacities. Under these circumstances, environmental contamination by SARS-CoV-2 in different areas one Portugal's major Hospitals was assessed between 21 January and 11 February 2021. Air samples (n = 44) were collected from eleven Hospital (four seven non-COVID-19 areas) using Coriolis® μ Compact cyclone air sampling devices. Surface also performed 17)...
Multimodal ligands are synthetic molecules comprising multiple types of interactions that have been increasingly used for the capture different biopharmaceutical compounds within complex biological mixtures. For monoclonal antibodies (mAbs) in particular, these shown possibility direct from cell culture supernatants native conditions, as well enhanced selectivity and affinity compared to traditional single-mode ligands. However, performing a target mAb using multimodal chromatography comes...