A5030531672- HER2/EGFR in Cancer Research
- Chemotherapy-induced cardiotoxicity and mitigation
- Cancer Treatment and Pharmacology
- Advanced Breast Cancer Therapies
- Breast Cancer Treatment Studies
- Neuroendocrine Tumor Research Advances
- Cancer Immunotherapy and Biomarkers
- Peptidase Inhibition and Analysis
- Monoclonal and Polyclonal Antibodies Research
- Prostate Cancer Treatment and Research
- Multiple and Secondary Primary Cancers
- Lung Cancer Research Studies
- Estrogen and related hormone effects
- Colorectal Cancer Treatments and Studies
- Metastasis and carcinoma case studies
- Cancer survivorship and care
- Nutrition and Health in Aging
- Cancer Diagnosis and Treatment
- Regional Development and Management Studies
- Pericarditis and Cardiac Tamponade
- Cancer, Stress, Anesthesia, and Immune Response
- Cardiac Fibrosis and Remodeling
- PI3K/AKT/mTOR signaling in cancer
- Metabolism, Diabetes, and Cancer
- Cardiac Imaging and Diagnostics
University Hospital Centre Zagreb
2013-2024
Klinički bolnički centar Osijek
2023
Sisters of Charity Hospital
2021
Sisters of Charity Hospital
2013-2018
Radiation Oncology Institute
2014
University of Chicago
2013
Nagoya Heart Center
2013
Karolinska University Hospital
2013
University of Zagreb
2011
Knowledge about the patient’s experience and perception of side effects their impact on daily life is crucial for adequate planning interventions to provide highest attainable levels quality during oncology treatment. We conducted a study consecutive samples 69 early breast cancer patients treated with four cycles neoadjuvant or adjuvant anthracycline-based chemotherapy. Patients completed questionnaire experienced after previous cycle The was modified PRO evaluation treatment toxicity...
Invasive ductal carcinoma is the most common type of breast cancer and accounts for about 70-85% all invasive carcinomas. It primarily metastasizes to bone, lungs, regional lymph nodes, liver brain. Most recurrence occurs within first 5 years diagnosis, particularly ER negative disease. Gastrointestinal tract involvement very rare detected in only 10% cases, it usually derives from lobular rather than much more cell cancer. Early diagnosis important because enables prompt adequate choice...
Abstract Trastuzumab has improved the prognosis of HER2 positive breast cancer, but cardiotoxicity remains a concern. We aimed to identify risk factors for trastuzumab-induced cardiotoxicity, with an emphasis on Ile655Val single nucleotide polymorphism. This single-center case–control study included 1056 patients early-stage cancer that received adjuvant trastuzumab. Cardiotoxicity was defined as decline in left ventricular ejection fraction (LVEF) > 15% without previous cardiomyopathy,...
Body composition changes could indicate health conditions and potential risks.Although several methods are currently available for quantitative assessment, each has limitations.Indirect most frequently used because of their availability simplicity.One those methods, which found wide use in clinical trials everyday practice was to be great value oncology patients, is bioelectrical impedance (BIA).Assessed muscle volume mass, measured by BIA, were associated with chemotherapy toxicity overall...
Serum chromogranin A (CgA) is routinely used as a biomarker in patients with neuroendocrine neoplasms (NENs). Several conditions and comorbidities may be associated falsely elevated CgA, often leading to extensive diagnostic evaluation, which costly harmful. The aim of this study was analyze the effectiveness acute octreotide suppression test (AOST) differentiating serum CgA.Our prospective enrolled 45 from two different patient cohorts: (1) 29 suspicion or presence NENs (extensive workup...
Tumor stimulates specific innate and acquired immune mechanisms.Main carriers of body's response to tumor are T lymphocytes main mechanism is killing cells by cytotoxic CD8 +.In some cases, system can also have a protumor role, which paradox, given that it known the inflammatory state promotes growth.One major characteristics tumors evading response, in particular mechanisms inhibition active antitumor via two physiological inhibitory signals, CTLA-4 PD1 / PDL1.Blockade these checkpoints,...
Abstract Aims This study aimed to investigate the association between tumor-infiltrating lymphocytes (TIL) and androgen receptors (AR) assess their impact on early triple-negative breast cancer (TNBC) prognosis. Previous studies analyzed only stromal TIL (sTIL) intratumoral (ITIL), while this includes an additional spatial analysis for in central tumor (CT) invasive margin (IM) compartments correlation with AR expression overall survival (OS). Methods A retrospective cohort encompassing 152...
Bolesnice s tumorom lijeve dojke, D/D genotipom za ACE i pozitivnom obiteljskom anamnezom kardiovaskularne bolesti imaju veci rizik razvoja kardiotoksicnosti na terapiju trastuzumabom stoga je kod takvih bolesnica potreban poseban obzir pracenja lijecenja.