- Acute Myocardial Infarction Research
- Cardiac Structural Anomalies and Repair
- Chemotherapy-induced cardiotoxicity and mitigation
- Coronary Interventions and Diagnostics
- Cardiac Imaging and Diagnostics
- Cardiovascular Function and Risk Factors
- Cardiac Valve Diseases and Treatments
- Vascular Procedures and Complications
- Cardiac pacing and defibrillation studies
- Cardiac electrophysiology and arrhythmias
- Peptidase Inhibition and Analysis
- HER2/EGFR in Cancer Research
- Parathyroid Disorders and Treatments
- Cardiac Arrhythmias and Treatments
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Pericarditis and Cardiac Tamponade
- Infective Endocarditis Diagnosis and Management
- Myasthenia Gravis and Thymoma
- Folate and B Vitamins Research
- Intraperitoneal and Appendiceal Malignancies
- Gout, Hyperuricemia, Uric Acid
- Aortic aneurysm repair treatments
- Eosinophilic Disorders and Syndromes
- Political Systems and Governance
- Cancer Treatment and Pharmacology
Catholic University of Croatia
2024
Sisters of Charity Hospital
2013-2023
University Hospital Centre Zagreb
2021-2022
The EUropean Comparative Effectiveness Research to Assess the Use of Primary ProphylacTic Implantable Cardioverter-Defibrillators (EU-CERT-ICD), a prospective investigator-initiated, controlled cohort study, was conducted in 44 centres and 15 European countries. It aimed assess current clinical effectiveness primary prevention ICD therapy.We recruited 2327 patients with ischaemic cardiomyopathy (ICM) or dilated (DCM) guideline indications for prophylactic implantation. endpoint all-cause...
OBJECTIVE Diabetes increases the risk of all-cause mortality and sudden cardiac death (SCD). The exact mechanisms leading to in diabetes are not well known. We compared incidence appropriate shocks patients with versus without a prophylactic implantable cardioverter defibrillator (ICD) included retrospective EU-CERT-ICD registry. RESEARCH DESIGN AND METHODS RESULTS A total 3,535 from 12 European centers mean age 63.7 ± 11.2 years (82% males) at time ICD implantation were analysis. 995 (28%)...
BACKGROUND:Amyloidosis is a multisystem disease caused by deposition of dysfunctional protein-amyloid-in various organs. The heart commonly involved, especially in primary (AL) and transthyretin (ATTR) amyloidosis. Most patients present with restrictive cardiomyopathy along other systemic features amyloid deposition. Diagnosing amyloidosis cumbersome based on the patient’s clinical condition findings from electrocardiography, routine laboratory tests, cardiac biomarkers, imaging, biopsy....
Coronary artery rupture is a rare complication of percutaneous coronary intervention (PCI) that may lead to pericardial effusion frequently accompanied by tamponade. It one the most serious complications with relatively high mortality rate ranging from 7 17%. 1-3 We report case 63-year-old patient acute inferoposterolateral ST-segment elevation myocardial infarction presented 4 hours beginning chest pain. An urgent coronarography left radial access was done and 3-vessel disease found...
Heart failure is the leading cause of morbidity and mortality worldwide, with ischemic heart disease being one most important etiologic factors.Heart develops due to ventricular remodeling, which leads increases in left end-systolic end-diastolic volumes.In this prospective observational study, we included 101 patients first episode ST-segment elevation myocardial infarction whom percutaneous coronary intervention was conducted within 12 h Thrombolysis Myocardial Infarction III flow...
Abstract A case presents a 37 years old patient who presented to emergency department with progression of dyspnea. Patient had history pulmonary hypertension due chronic thromboembolism and known, repetitive thrombosis both legs them postthrombotically altered, especially left leg. During his workup he angiography performed which showed evidence in right main branch circumferential pericardial effusion was dominantly locularized behind ventricular posterior wall. Emergency echocardiography...
E mail: matias.trbusic@gmail.com Amiodarone-induced thyrotoxicosis (AIT) is a serious medical problem especially in patients with dilatative cardiomyopathy because of substantial rate morbidity and mortality. Patients usually present as worsening arrhythmias congestive heart failure. Two forms AIT have been described. Type I occurs preexisting adenomatous goiter results from the excessive hormone production secondary to iodine excess. II found without thyroid disease chemical-induced...
2. Trbusic M, Gabric ID, Planinc D, Krcmar T, Pintaric H. What happens when transradialists use transbrachial approach. J Invasive Cardiol. 2013;25 (Suppl E):30E. UvOD: Od 2011. primarni postav naseg laboratorija za invazivnu kardiologiju promijenjen je s femoralnog u lijevi radijalni i danas se oko 95% svih postupaka ucini lijevim ili desnim „nefemoralnim“ pristupom. Primarna perkutana koronarna intervencija (PCI) bolesnika infarktom miokarda elevacijom ST-segmenta (STEMI) najzahtjevniji...
Purpose: Radial arterial approach has become the default option for coronary procedures in our cath lab (>90%).However, there are situations when radial is not possible (e.g.congenital anomalies, tortuous configurations, radioulnar loop, weak or absent pulse secondary to previous puncture catheterization).In such situations, a common second-line used (femoral ulnar).Many clinicians considered transbrachial (TB) angiography as high-risk and an obsolete procedure.In literature, complication...
Bolesnice s tumorom lijeve dojke, D/D genotipom za ACE i pozitivnom obiteljskom anamnezom kardiovaskularne bolesti imaju veci rizik razvoja kardiotoksicnosti na terapiju trastuzumabom stoga je kod takvih bolesnica potreban poseban obzir pracenja lijecenja.
Abstract Introduction Transthyretin amyloidosis (ATTR) is classified as hereditary (hATTR) or acquired (wtATTR). hATTR rare genetic disease with variable penetrance and phenotype, cardiomyopathy (CM) and/or neuropathy being most relevant clinical presentations. The common investigated mutation in Europe Val30Met, predominant endemic areas of Portugal Sweden. On the contrary, p.Asp38Glu an extremely only several cases mentioned a Swedish register isolated Japan, India Canada. Described were...
Transthoracic echocardiography (TTE)is the primary diagnostic method for assessment of cardiotoxicity and immunotherapy is canceled or suspended if left ventricular ejection fraction (LVEF) reduced more 15% from baseline by 10-15% normal values. In our study, 130 patients (pts) with breast cancer werw treated trastuzumab adjuvantly one year. According to guidelines, TTE was performed before beginning in 3 months periods during therapy. Pts were divided two groups: 51 pts proven listed group...