A5002584771- T-cell and B-cell Immunology
- Immune Cell Function and Interaction
- Hematopoietic Stem Cell Transplantation
- Urticaria and Related Conditions
- Cardiovascular Function and Risk Factors
- Cardiac pacing and defibrillation studies
- Dermatology and Skin Diseases
- Contact Dermatitis and Allergies
- Immunotherapy and Immune Responses
- Cardiac electrophysiology and arrhythmias
- Digital Mental Health Interventions
- Telemedicine and Telehealth Implementation
- Mobile Health and mHealth Applications
University of Göttingen
2014-2022
Universitätsmedizin Göttingen
2022
Charité - Universitätsmedizin Berlin
2011
Glucocorticoids (GCs) are released from the adrenal gland during inflammation and help to keep immune responses at bay. Owing their potent anti-inflammatory activity, GCs also play a key role in controlling acute graft-versus-host disease (aGvHD). Here we demonstrate that mice lacking glucocorticoid receptor (GR) T cells develop fulminant after allogeneic bone marrow transplantation. In fully MHC-mismatched model, transfer of GR-deficient resulted severe aGvHD symptoms strongly decreased...
// Tina Baake 1 , Katharina Jörß Jennifer Suennemann Laura Roßmann Hanibal Bohnenberger 2 Jan P. Tuckermann 3 Holger M. Reichardt 1, * Henrike J. Fischer 4, and Sybille D. Institute for Cellular Molecular Immunology, University Medical Center, Georg-August-University Göttingen, Germany of Pathology, Comparative Endocrinology, Ulm, 4 Present address: Multiple Sclerosis Research Neuroimmunology, These authors share senior authorship Correspondence to: Reichardt, email:...
OBJECTIVE Diabetes increases the risk of all-cause mortality and sudden cardiac death (SCD). The exact mechanisms leading to in diabetes are not well known. We compared incidence appropriate shocks patients with versus without a prophylactic implantable cardioverter defibrillator (ICD) included retrospective EU-CERT-ICD registry. RESEARCH DESIGN AND METHODS RESULTS A total 3,535 from 12 European centers mean age 63.7 ± 11.2 years (82% males) at time ICD implantation were analysis. 995 (28%)...
In recent years, the use of digital mobile measurement devices (DMMDs) for self-documentation in cardiovascular care Western industrialized health systems has increased. For patients with chronic heart failure (cHF), plays an increasingly important role self-management. Data from DMMDs can also be integrated into telemonitoring programs or data-intensive medical research to collect and evaluate patient-reported outcome measures through data sharing. However, implementation sharing poses...