Simon Schlögl
A5009525051- Cardiac pacing and defibrillation studies
- Cardiac Arrhythmias and Treatments
- Cardiac electrophysiology and arrhythmias
- Atrial Fibrillation Management and Outcomes
- Cardiovascular Syncope and Autonomic Disorders
- Cardiomyopathy and Myosin Studies
- ECG Monitoring and Analysis
- Heart Rate Variability and Autonomic Control
- Cardiac Imaging and Diagnostics
- Cardiovascular Function and Risk Factors
- Cardiac Health and Mental Health
University Medical Center
2025
Universitätsmedizin Göttingen
2018-2024
University of Göttingen
2020-2024
German Centre for Cardiovascular Research
2020-2024
The EUropean Comparative Effectiveness Research to Assess the Use of Primary ProphylacTic Implantable Cardioverter-Defibrillators (EU-CERT-ICD), a prospective investigator-initiated, controlled cohort study, was conducted in 44 centres and 15 European countries. It aimed assess current clinical effectiveness primary prevention ICD therapy.We recruited 2327 patients with ischaemic cardiomyopathy (ICM) or dilated (DCM) guideline indications for prophylactic implantation. endpoint all-cause...
Cardioneuroablation is a treatment option for patients with recurrent vasovagal syncope (VVS). Ablation targets of parasympathetic ganglionated plexi (GP) adjacent to the right and left atrial walls distal endocardial inputs these GP can be identified both by their anatomical localization intracardiac mapping fragmented electrogram signals. In this case successful cardioneuroablation 22-year-old patient suffering from VVS, new algorithm automatic signals (CARTO Elevate Module, Biosense...
Abstract Aims Fragmented QRS complex with visible notching on standard 12-lead electrocardiogram (ECG) is understood to represent depolarization abnormalities and signify risk of cardiac events. Depolarization similar prognostic implications likely exist beyond visual recognition but no technology presently suitable for quantification such invisible ECG abnormalities. We present a technology. Methods results A signal processing method projects all leads the into optimized three perpendicular...
BackgroundCardiac autonomic dysfunction after myocardial infarction identifies patients at high risk despite only moderately reduced left ventricular ejection fraction. We aimed to show that telemedical monitoring with implantable cardiac monitors in these can improve early detection of subclinical but prognostically relevant arrhythmic events.MethodsWe did a prospective investigator-initiated, randomised, multicentre, open-label, diagnostic trial 33 centres Germany and Austria. Survivors...
Abstract Introduction Pulsed-field energy (PFA) and very high-power short-duration radiofrequency (vHPSD-RF) are two novel ablation methods for pulmonary vein isolation (PVI). Both PFA vHPSD-RF show promise improving efficacy, safety, reducing procedure durations. However, direct comparisons between these techniques scarce. Methods results Retrospective analysis of 82 patients with symptomatic AF. Of these, 52 received 30 (90 W, 4 s) as index procedure. At the 6-month follow-up, AF...
Abstract Aims The clinical effectiveness of primary prevention implantable cardioverter defibrillator (ICD) therapy is under debate. EUropean Comparative Effectiveness Research to Assess the Use Primary ProphylacTic Implantable Cardioverter Defibrillators (EU‐CERT‐ICD) aims assess its current value. Methods and results EU‐CERT‐ICD a prospective investigator‐initiated non‐randomized, controlled, multicentre observational cohort study performed in 44 centres across 15 European Union countries....
OBJECTIVE Diabetes increases the risk of all-cause mortality and sudden cardiac death (SCD). The exact mechanisms leading to in diabetes are not well known. We compared incidence appropriate shocks patients with versus without a prophylactic implantable cardioverter defibrillator (ICD) included retrospective EU-CERT-ICD registry. RESEARCH DESIGN AND METHODS RESULTS A total 3,535 from 12 European centers mean age 63.7 ± 11.2 years (82% males) at time ICD implantation were analysis. 995 (28%)...
Abstract Background Data comparing remote magnetic catheter navigation (RMN) with manual (MCN) ablation of atrial fibrillation (AF) is lacking. The aim the present prospective observational study was to compare outcome RMN versus (vs.) MCN AF regards recurrence. Methods comprised 667 consecutive patients a total 939 procedures: 287 were ablated using RMN, 380 MCN. Results There no significant difference between groups at baseline. After 2.3 ± years follow‐up, 23% in group remained free...
Objective To test the hypothesis that in recipients of primary prophylactic implantable cardioverter-defibrillators (ICDs), non-planarity ECG vector loops predicts (a) deaths despite ICD protection and (b) appropriate shocks. Methods Digital pre-implant ECGs were collected 1948 recipients: 21.4% females, median age 65 years, 61.5% ischaemic heart disease (IHD). QRS T wave three-dimensional constructed using singular value decomposition allowed to measure loop planarity. The non-planarity,...
Abstract Aim The association of standard 12-lead electrocardiogram (ECG) markers with benefits the primary prophylactic implantable cardioverter-defibrillator (ICD) has not been determined in contemporary era. We analysed traditional and novel ECG variables a large prospective, controlled ICD population to assess predictive value terms benefit. Methods results Electrocardiograms from 1477 patients 700 control (EU-CERT-ICD; non-randomized, controlled, prospective multicentre study;...
In atrial fibrillation (AF) patients, catheter ablation of pulmonary veins (PVI) is the most effective therapeutic option to maintain sinus rhythm. To improve successful PVI, contact force-sensing (CF) catheters became routinely available. Previous studies did not clearly show superior clinical efficacy in comparison with non-CF catheters.We investigated consecutive who underwent index PVI for AF at our hospital between 2012 and 2018. Three hundred fifty-four patients were ablated without...
Abstract Background Data comparing remote magnetic catheter navigation (RMN) with manual in combination contact force sensing (MCN-CF) ablation of atrial fibrillation (AF) is lacking. The primary aim the present retrospective comparative study was to compare outcome RMN versus (vs.) MCN-CF AF regards recurrence. Secondary analyze periprocedural risk, characteristics and repeat procedures. Methods We retrospectively analyzed 452 patients undergoing a total 605 ablations AF: 180 were ablated...
New methods to identify patients who benefit from a primary prophylactic implantable cardioverter-defibrillator (ICD) are needed. T-wave alternans (TWA) has been shown associate with arrhythmogenesis of the heart and sudden cardiac death. We hypothesized that TWA might be associated ICD implantation in prevention.
Abstract Funding Acknowledgements Type of funding sources: None. Background/Introduction Implantable loop recorders (ILR) are increasingly used for continuous rhythm monitoring following pulmonary vein isolation (PVI) atrial fibrillation (AF). However, the impact non-AF episodes in this patient population is unknown. Purpose Firstly, aim our study was to asses incidence clinically important events. Secondly, we wanted identify possible risk factors leading incidental Methods In retrospective...
Abstract Funding Acknowledgements Type of funding sources: None. Background In atrial fibrillation (AF) patients, pulmonary vein isolation by means catheter ablation (CA) is the most effective therapeutic option in order to maintain sinus rhythm. To improve successful PV and lesion creation, contact force (CF)-sensing catheters were developed have become routinely available. Previous studies did not always show superior clinical efficacy comparison with non-CF CA. Moreover, data about long...
Abstract Background New methods to identify patients who truly benefit from primary prophylactic implantable cardioverter defibrillation (ICD) are urgently needed. T-wave alternans (TWA) represents a beat-to-beat fluctuation in the morphology of ST-segment and T-wave. It has been shown associate with arrhythmogenesis heart sudden cardiac death [1]. We hypothised that TWA might ICD implantation prevention. Methods In EU-CERT-ICD study, we prospectively enrolled 2327 candidates 15 European...