- Cardiac Arrhythmias and Treatments
- Atrial Fibrillation Management and Outcomes
- Cardiac pacing and defibrillation studies
- Cardiac electrophysiology and arrhythmias
- Venous Thromboembolism Diagnosis and Management
- Central Venous Catheters and Hemodialysis
- Cardiac Imaging and Diagnostics
- Cardiovascular Syncope and Autonomic Disorders
- Cardiovascular Function and Risk Factors
- Mechanical Circulatory Support Devices
- Cardiomyopathy and Myosin Studies
- Viral Infections and Immunology Research
- Microscopic Colitis
- Dementia and Cognitive Impairment Research
- Inflammatory Bowel Disease
- Hormonal Regulation and Hypertension
- ECG Monitoring and Analysis
- Intracranial Aneurysms: Treatment and Complications
- Advanced Neural Network Applications
- Heart Failure Treatment and Management
- Vitamin K Research Studies
- Pneumothorax, Barotrauma, Emphysema
- Infection Control and Ventilation
- Operations Management Techniques
- Hedgehog Signaling Pathway Studies
Semmelweis University
2015-2025
Jahn Ferenc Dél-Pesti Kórház és Rendelőintézet
2006-2024
United Heart and Vascular Clinic
2022
University of Pecs
2021
University of Debrecen
2021
Universitatea de Medicină, Farmacie, Științe și Tehnologie „George Emil Palade” din Târgu Mureș
2018
The EUropean Comparative Effectiveness Research to Assess the Use of Primary ProphylacTic Implantable Cardioverter-Defibrillators (EU-CERT-ICD), a prospective investigator-initiated, controlled cohort study, was conducted in 44 centres and 15 European countries. It aimed assess current clinical effectiveness primary prevention ICD therapy.We recruited 2327 patients with ischaemic cardiomyopathy (ICM) or dilated (DCM) guideline indications for prophylactic implantation. endpoint all-cause...
BACKGROUND: High-power short-duration ablation has shown impressive efficacy and safety for pulmonary vein isolation (PVI); however, initial results with very high power were discouraging. This study compared the long-term durability of PVI performed a 90- versus 50-W setting. METHODS: Patients randomized 1:1 to undergo QDOT catheter using setting 90 or 50 W. Three months after index procedure, patients underwent repeat electrophysiology identify reconnections. followed 12 detect AF...
Atrial fibrillation (AF) ablation has made huge progress with respect to innovation, efficacy, and safety, however, complications are still present. Recent studies examined various predictors of complications. However, limited data exist regarding the role a repeat procedure. Our aim was prospective evaluation incidence related AF procedures in consecutive patients, including procedures.All for between January 2013 December 2015 were analysed our electrophysiology laboratory. During study...
Introduction Our pilot study aimed to evaluate the role of local impedance drop in lesion formation during pulmonary vein isolation with a novel contact force sensing ablation catheter that records as well and find cut-off value predicts successful formation. Materials methods After completing point-by-point radiofrequency isolation, success applications was evaluated by pacing along line at 10 mA, 2 ms pulse width. Lesions were considered if loss capture achieved. Results Out 645...
The role of the spatial relationship between left superior pulmonary vein (LSPV) and atrial appendage (LAA) is unknown. We sought to evaluate whether an abutting LAA LSPV play a in AF recurrence after catheter ablation for paroxysmal AF.Consecutive patients, who underwent initial point-by-point radiofrequency at Heart Vascular Center Semmelweis University, Budapest, Hungary, January 2014 December 2017, were enrolled study. All patients pre-procedural cardiac CT assess (LA) (PV) anatomy....
High-power short-duration (HPSD) radiofrequency ablation has been proposed to produce rapid and effective lesions for pulmonary vein isolation (PVI). We aimed evaluate the procedural characteristics first-pass (FPI) rate of HPSD very high-power (vHPSD) compared low-power long-duration (LPLD) technique. One hundred fifty-six patients with atrial fibrillation (AF) were enrolled assigned LPLD, HPSD, or vHPSD PVI. The energy setting was 30, 50, 90 W in groups, respectively. In group, W/4 s...
Abstract Aims Cerebral thrombo-embolism is a dreaded complication of pulmonary vein isolation (PVI) for atrial fibrillation; its surrogate, silent cerebral embolism (SCE) can be detected by diffusion-weighted brain magnetic resonance imaging (bMRI). Initial investigations have raised concern that very high-power, short-duration (vHPSD; 90 W/4 s) temperature-controlled PVI with the QDOT Micro catheter may associated higher incidence SCE compared low-power long-duration ablation. We aimed to...
According to current guidelines, pulmonary vein isolation as first-line therapy should be considered for patients with atrial fibrillation (AF), however, optimal timing of the procedure is still unknown in heart failure (HF). We aimed evaluate effect early catheter ablation (CA) HF and left ventricular ejection fraction (LVEF) below 50%.
Nowadays, a novel contact-force guided ablation technique is used for enclosing pulmonary veins in patients with atrial fibrillation (AF). We sought to determine whether left (LA) wall thickness (LAWT) and vein (PV) dimensions, as assessed by cardiac CT, could influence the success rate of first-pass isolation (PVI). In single-center, prospective study, we enrolled consecutive symptomatic, drug-refractory AF who underwent initial radiofrequency catheter using modified CLOSE protocol....
The aim of our study was to investigate the long-term efficacy and safety transseptal endocardial left ventricular lead implantation (TELVLI).Transseptal performed in 54 patients (44 men, median age 69, New York Heart Association III-IV stage) between 2007 2017 a single centre. In 36 cases, puncture (TP) via femoral vein, 18 TP also (LV) placement were subclavian vein. An electrophysiological deflectable catheter used reach LV wall through dilated hole. successful all patients. A total...
Interventional cardiology procedures may expose patients and staff to considerable radiation doses. We aimed assess whether exposure ionizing during catheter ablation of supraventricular tachycardia (SVT) can be completely avoided.In this prospective randomized study, with SVT (atrioventricular re-entrant n = 94, typical atrial flutter 29) were randomly assigned in a 1:1 ratio conventional fluoroscopic guidance (CF group) or the EnSite Precision mapping system [zerofluoro (ZF) group]. Acute...
Introduction Pulmonary vein isolation is the cornerstone of rhythm-control therapy for atrial fibrillation (AF). The very high-power, short-duration (vHPSD) radiofrequency (RF) ablation a novel technology that favors resistive heating while decreasing role conductive heating. Our study aimed to evaluate correlations between contact force (CF), power, impedance drop (ID), and temperature; assess their in lesion formation with vHPSD technique. Methods Consecutive patients who underwent initial...
Background: Atrial fibrillation (AF) recurrence after pulmonary vein isolation (PVI) is predominantly attributed to reconnection (PVR). Predictors of AF have been widely studied; however, data are scarce on procedural parameters that predict chronic PVR. We aimed study PVR rates and predictors Methods: retrospectively included 100 patients who underwent repeated ablation due initial PVI with the CARTO system. was determined during procedure by electrophysiological evaluation, characteristics...
Despite significant improvements in cardiac output and functional capacity with resynchronization therapy (CRT), incidence of sudden death still remains high. Reversal physiological myocardial activation sequence during epicardial pacing increases the transmural dispersion repolarization (TDR). The aim this study was to compare effects endocardial biventricular on parameters same patient group.Seven patients who had transseptal left ventricle (LV) lead placement, whom CRT failed due coronary...
Abstract Aims Unlike in atrial fibrillation ablation, there is a lack of appropriately sized and properly designed studies regarding outflow tract (OT) premature ventricular complex (PVC) ablation outcomes with contact force sensing (CFS) catheters. We aimed to compare the acute success-, complication-, long-term recurrence rates manual CFS catheters traditional irrigated (T) OT PVC ablation. Methods results Single-centre, propensity-matched data 75–75 patients ablated for right-sided (RVOT)...
Abstract Aim The association of standard 12-lead electrocardiogram (ECG) markers with benefits the primary prophylactic implantable cardioverter-defibrillator (ICD) has not been determined in contemporary era. We analysed traditional and novel ECG variables a large prospective, controlled ICD population to assess predictive value terms benefit. Methods results Electrocardiograms from 1477 patients 700 control (EU-CERT-ICD; non-randomized, controlled, prospective multicentre study;...
The efficiency of pulmonary vein isolation (PVI) depends on the durability RF lesions. Recent studies documented sustained continuity ablation lines, improvements in durability, and expected clinical outcomes through altered settings duration power. However, strategy has not been adapted to this new approach different biophysics lesion formation.
Purpose Our purpose was to compare the procedural characteristics, success rate, and complication rate of conventional fluoroscopic (CF) zero-fluoroscopic (ZF) approach in patients undergoing catheter ablation AVNRT or typical atrial flutter (Aflu). Methods 186 consecutive with an indication for Aflu were enrolled. Based on operator's preference, assigned either CF ZF group. In group EnSite NavX, Carto3, Rhythmia EAMS used guidance. Results The median age 56 (IQR = 42−68) years, 144 had...
Aims We aimed to establish sex-specific predictors for 1-year VT recurrence and all-cause mortality in patients with structural heart disease undergoing catheter ablation. Methods analyzed data of 299 recorded our structured registry. These included medical history, echocardiography parameters, laboratory results, properties, procedural data. Results Out the patients, 34 (11%) were female. No significant difference was found between women men terms ( p = 0.74) or 0.07). In females, severe...
Background: Safety, efficacy, and patient comfort are the expectations during pulmonary vein isolation (PVI). We aimed to validate combined advantages of pre- periprocedural anticoagulation with non-vitamin K anticoagulants (NOACs) rigorous left atrial appendage thrombus (LAAT) exclusion computed tomography (CT). Methods: This study included a population consecutive patients, between March 2018 June 2020, who underwent cardiac CT within 24 h before PVI guide ablation rule out LAAT. NOAC was...