A5050065572- Cardiac Arrhythmias and Treatments
- Atrial Fibrillation Management and Outcomes
- Cardiac electrophysiology and arrhythmias
- Cardiac pacing and defibrillation studies
- Cardiac Imaging and Diagnostics
- Cardiovascular Function and Risk Factors
- Cardiovascular Effects of Exercise
- Venous Thromboembolism Diagnosis and Management
- ECG Monitoring and Analysis
- Blood Pressure and Hypertension Studies
- Advanced MRI Techniques and Applications
- Cardiovascular Syncope and Autonomic Disorders
- Heart Rate Variability and Autonomic Control
- Radiation Dose and Imaging
- Social Media in Health Education
- Cardiac Ischemia and Reperfusion
- Health Systems, Economic Evaluations, Quality of Life
- Heart Failure Treatment and Management
- Heart rate and cardiovascular health
- Cardiac Structural Anomalies and Repair
- Antiplatelet Therapy and Cardiovascular Diseases
- Cardiac Arrest and Resuscitation
- Mobile Health and mHealth Applications
- Public Administration and Political Analysis
- Health Literacy and Information Accessibility
Helios Kliniken
2018-2024
Leipzig Heart Institute
2012-2023
Helios Park-Klinikum Leipzig
2017-2023
Leipzig University
2006-2021
Medical University of Warsaw
2020-2021
Mayo Clinic
2018
Boston Scientific (Germany)
2018
Mayo Clinic in Arizona
2018
University Hospital Leipzig
2016-2017
South Australian Health and Medical Research Institute
2017
Abstract There is an increasing proportion of the general population surviving to old age with significant chronic disease, multi-morbidity, and disability. The prevalence pre-frail state frailty syndrome increases exponentially advancing associated greater morbidity, disability, hospitalization, institutionalization, mortality, health care resource use. Frailty represents a global problem, making early identification, evaluation, treatment prevent cascade events leading from functional...
Recurrences of atrial fibrillation (AF) occur in up to 30% within 1 year after catheter ablation. This study evaluated the value CHADS2, R2CHADS2, and CHA2DS2-VASc scores for prediction rhythm outcomes AF ablation.Using Leipzig Heart Center Ablation Registry, we documented first 12 months 2069 patients (67% men; 60±10 years; 35% persistent AF) undergoing recurrences were defined as any arrhythmia occurring week (early recurrences, ERAF) between 3 (late LRAF) ERAF LRAF occurred 36% 33%,...
Coupling between the ablation catheter and myocardium is critical to resistively heat tissue with radiofrequency ablation. The objective of this study was evaluate whether a novel local impedance (LI) measurement on an identifies catheter-tissue coupling predictive lesion formation.LI studied in explanted hearts (n=10 swine) vivo (n=10; 50-70 kg using investigational electroanatomic mapping system that measures from mini-electrodes incorporated distal electrode (Rhythmia IntellaNav MiFi OI,...
We aim to provide a critical appraisal of basic concepts underlying signal recording and processing technologies applied for (i) atrial fibrillation (AF) mapping unravel AF mechanisms and/or identifying target sites therapy (ii) detection, optimize usage technologies, stimulate research aimed at closing knowledge gaps, developing ideal technologies. Recording techniques assessment electrical activity during essential diagnosis guiding ablative including body surface electrocardiograms (ECG)...
Abstract Background Multiple wearable devices for rhythm analysis have been developed using either photoplethysmography (PPG) or handheld ECG. Hypothesis The aim of this survey was to assess impact these technologies on physicians' clinical decision‐making regarding initiation diagnostic steps, drug therapy, and invasive strategies. Methods online included 10 questions types devices, advantages, disadvantages as well case scenarios patients with supraventricular arrhythmias atrial...
Abstract Novel wearable devices for heart rhythm analysis using either photoplethysmography (PPG) or electrocardiogram (ECG) are in daily clinical practice. This survey aimed to assess impact of these technologies on physicians’ decision-making and define, how data from should be presented integrated into The online included 22 questions, focusing the diagnosis atrial fibrillation (AF) based device recordings, suitable indications devices, presentation processing, reimbursement, future...
Social media (SoMe) represents a medium of communication in everyday life and has gained importance for professional use among clinicians. In the #intEHRAct survey, we aimed to describe SoMe by healthcare community setting. The EHRA e-Communication Committee Scientific Initiatives prepared questionnaire distributed it via newsletters, Twitter, LinkedIn, Facebook. survey consisted 19 questions made on an individual basis collected anonymously. Two hundred eighty-five responders from 35...
Abstract The aims of this centre-based survey, promoted and disseminated by the European Heart Rhythm Association (EHRA) was to investigate current practice for investigation Sudden Unexplained Death in Young (SUDY) amongst countries. An online questionnaire composed 21 questions submitted EHRA Research Network, Cardiac Arrhythmia Genetics (ECGen) Focus Group members, Reference Network GUARD-Heart healthcare partners. There were 81 respondents from 24 majority (78%) worked a dedicated clinic...
The use of a blanking period (BP) after an atrial fibrillation (AF) ablation procedure is common practice, but recent data questions the benign nature early recurrences tachyarrhythmias (ERATs). A physician-based survey was carried out by European Heart Rhythm Association (EHRA) to investigate current definition and applicability BP ERAT management. An online questionnaire sent clinical interventional electrophysiologists. total 436 respondents (88% electrophysiologists) reported observing...
There are limited data on the predictive value of stroke risk scores for thromboembolic events (TEs) after catheter ablation atrial fibrillation (AF). Our objectives were to report incidence TEs AF in a large contemporary cohort and investigate impact renal dysfunction stratification (CHADS2, CHA2DS2-VASc, R2CHADS2) predicting TE ablation.Using Leipzig Heart Center Ablation Registry, we documented patients undergoing radiofrequency ablation. was defined as stroke, transient ischemic attack,...
Background— Recent studies reported worse outcomes after atrial fibrillation (AF) ablation in patients with metabolic syndrome (MetS). However, mechanisms of AF recurrence MetS remain unclear. Method and Results— We performed pulmonary vein isolation voltage mapping 236 (age 61±9.6 years; persistent 64%; 54%). Left (LA) low areas were semiquantitatively estimated presented as index. was defined according to National Cholesterol Education Program Adult Treatment Panel III. Follow-up for ≤12...
Randomized controlled trials demonstrate that remote monitoring (RM) of implantable cardioverter-defibrillators (ICDs) and cardiac resynchronization therapy devices (CRT-Ds) may improve quality care prognosis in heart failure (HF) patients. However, the impact RM on long-term mortality a real-world cohort is still not well examined.This study was designed as matched based COMMIT-HF trial--a single-center, ongoing prospective observational registry (NCT02536443). Complete patient...
Ultra High‐Density Mapping of the Right Atria Introduction Recently, an automatic, high‐resolution mapping system has been presented to accurately and quickly identify right atrial geometry activation patterns in animals, but human data are lacking. This study aims assess clinical feasibility accuracy high‐density electroanatomical various RA arrhythmias. Methods Results Electroanatomical maps (35 partial 24 complete) were created 23 patients using a novel mini‐basket catheter with 64...
Left ventricular diastolic dysfunction (LVDD) is common in the general population, but its prevalence atrial fibrillation (AF), predictors for LVDD AF and association between AF-related symptom severity has not been well studied.In 124 consecutive patients (mean age 61 ± 11years, 60% male) with paroxysmal (n = 70) or persistent 54) referred catheter ablation, was evaluated according to current guidelines using transthoracic echocardiography. quantified European Heart Rhythm Association...
AimsThe safety and efficacy of novel oral anticoagulants in patients with atrial fibrillation undergoing pacemaker or implantable cardioverter-defibrillator interventions have not been clearly defined. Therefore, we compared the incidence bleeding thrombo-embolic complications following cardiac rhythm device (CRD) implantations under dabigatran vs. rivaroxaban a real-world cohort.
Aims This study investigated the possible association between hs-CRP as well changes and rhythm outcome after AF catheter ablation. Methods We studied 68 consecutive patients with undergoing levels were measured using commercially available assays before 6 months Serial 7-day Holter ECGs used to detect recurrences. Results Early recurrence (ERAF, within one week) was observed in 38%, while late (LRAF, 3 months) occurred 18% of patients. None baseline clinical or echocardiographic variables...
Although sinus node modification by catheter ablation is an established therapy for the treatment of inappropriate tachycardia, there incomplete understanding anatomy and function but also limited electroanatomical mapping data. Recently, automatic, ultra high-resolution system has been presented to accurately quickly identify right atrial (RA) geometry activation patterns detailed assessment not performed which was one aim this study. Preclinical experiences are compared with previous...
Recurrence of atrial fibrillation (AF) is frequently observed after AF catheter ablation. However, the predictive value echocardiographic parameters associated with left ventricular diastolic dysfunction (LVDD) has not been well studied.In 124 consecutive patients (mean age 61 ± 10 years, 60% male) paroxysmal (n = 70) or persistent 54) undergoing ablation, mitral early peak (E-wave) and late (A-wave) velocities, E/A ratio, deceleration time (DT) velocity, annulus velocity (e'), E/e' ratio...