A5024752712- Cardiac Arrhythmias and Treatments
- Atrial Fibrillation Management and Outcomes
- Cardiac electrophysiology and arrhythmias
- Cardiac pacing and defibrillation studies
- ECG Monitoring and Analysis
- Cardiovascular Function and Risk Factors
- Cardiac Imaging and Diagnostics
- Sarcoidosis and Beryllium Toxicity Research
- Heart Rate Variability and Autonomic Control
- Cardiovascular Syncope and Autonomic Disorders
- Congenital Heart Disease Studies
- Cardiomyopathy and Myosin Studies
- Cardiac Structural Anomalies and Repair
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Cardiovascular Effects of Exercise
- Viral Infections and Immunology Research
- Blood Pressure and Hypertension Studies
- Microbial Inactivation Methods
- Advanced MRI Techniques and Applications
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Cardiac Valve Diseases and Treatments
- Obstructive Sleep Apnea Research
- Cardiovascular Health and Risk Factors
- Pulmonary Hypertension Research and Treatments
- Health Systems, Economic Evaluations, Quality of Life
Mayo Clinic in Arizona
2016-2025
Mayo Clinic
2015-2024
WinnMed
2009-2024
Mayo Clinic in Florida
2009-2024
Mayo Clinic Hospital
2024
University of Minnesota
2021
E Ink (South Korea)
2020
London School of Hygiene & Tropical Medicine
2020
Amsterdam UMC Location University of Amsterdam
2009-2019
University of Pennsylvania
2009-2018
Background— Genetic testing for long-QT syndrome (LQTS) has diagnostic, prognostic, and therapeutic implications. Hundreds of causative mutations in 12 known LQTS-susceptibility genes have been identified. that includes the 3 most commonly mutated is available clinically. Distinguishing pathogenic from innocuous rare variants critical to interpretation test results. We sought quantify value mutation type gene/protein region determining probability pathogenicity mutations. Methods Results—...
Sex and age have long been known to affect the ECG. Several biologic variables anatomic factors may contribute sex age-related differences on We hypothesized that a convolutional neural network (CNN) could be trained through process called deep learning predict person's self-reported using only 12-lead ECG signals. further discrepancies between CNN-predicted chronological serve as physiological measure of health.We CNNs 10-second samples signals from 499 727 patients age. The networks were...
Deep learning algorithms derived in homogeneous populations may be poorly generalizable and have the potential to reflect, perpetuate, even exacerbate racial/ethnic disparities health care. In this study, we aimed (1) assess whether performance of a deep algorithm designed detect low left ventricular ejection fraction using 12-lead ECG varies by race/ethnicity (2) determine its is determined derivation population or racial variation ECG.We performed retrospective cohort analysis that...
Criteria have not been established for identifying LA scar using electroanatomic mapping (EAM). It is also unclear if voltage criteria EAM may assist in areas of pulmonary vein (PV) reconnection patients undergoing repeat AF ablation.To characterize left atrial (LA) fibrillation (AF) ablation.An shell was created and bipolar amplitude (in mV) at each point measured. The divided into 8 regions. Bipolar values lower than the 95% sampled points used as upper cutoff value. Delayed enhancement...
Abstract Objectives We sought to validate a deep learning algorithm designed predict an ejection fraction (EF) less than or equal 35% based on the 12‐lead electrocardiogram (ECG) in large prospective cohort. Background Patients undergoing routine ECG may have undetected left ventricular (LV) dysfunction that warrants further echocardiographic assessment. However, identification of these patients can be challenging. Methods applied all ECGs interpreted by Mayo Clinic laboratory September...
Background— Although the vast majority of mitral valve prolapse (MVP) is benign, a small subset patients, predominantly women, with bileaflet prolapse, complex ventricular ectopy (VE), and abnormal T waves comprise recently described MVP syndrome. We compared findings on electrophysiological study in syndrome patients without cardiac arrest to identify factors that may predispose malignant arrhythmia. Methods Results— Fourteen consecutive (n=13 women; median [limits], age at index ablation,...
Percutaneous stellate ganglion blockade (SGB) has been used for drug-refractory electrical storm due to ventricular arrhythmia (VA); however, the effects and long-term outcomes have not well studied. This study included 30 consecutive patients who had underwent percutaneous SGB between October 1, 2013, March 31, 2018. Bupivacaine, alone or combined with lidocaine, was injected into neck good local anesthetic spread in vicinity of left (n=15) both ganglia (n=15). Data were collected patient...
Assessing Arrhythmia Burden After Ablation Introduction monitoring in patients undergoing atrial fibrillation (AF) ablation is challenging. Transtelephonic monitors (TTMs) are cumbersome to use and provide limited temporal assessment. Implantable loop recorders (ILRs) may overcome these limitations. We sought evaluate the utility of ILRs versus conventional (CM) AF ablation. Methods Results Forty‐four received CM (30‐day TTM at discharge months 5 11 postablation). Over initial 6 months,...
Coupling between the ablation catheter and myocardium is critical to resistively heat tissue with radiofrequency ablation. The objective of this study was evaluate whether a novel local impedance (LI) measurement on an identifies catheter-tissue coupling predictive lesion formation.LI studied in explanted hearts (n=10 swine) vivo (n=10; 50-70 kg using investigational electroanatomic mapping system that measures from mini-electrodes incorporated distal electrode (Rhythmia IntellaNav MiFi OI,...
Containment, the key strategy in quickly halting an epidemic, requires rapid identification and quarantine of infected individuals, determination whom they have had close contact with previous days weeks, decontamination locations individual has visited. Achieving containment demands accurate timely collection individual's location history. Traditionally, this process is labor intensive, susceptible to memory errors, fraught privacy concerns. With recent almost ubiquitous availability smart...
Background The prognosis of left ventricular noncompaction (LVNC) remains elusive despite its recognition as a clinical entity for >30 years. We sought to identify and imaging characteristics risk factors mortality in patients with LVNC. Methods Results 339 adults LVNC seen between 2000 2016 were identified. was defined end-systolic noncompacted compacted myocardial ratio >2 (Jenni criteria) end-diastolic trough trabeculation-to-epicardium (X):peak (Y) <0.5 (Chin by echocardiography;...