- Cardiac Arrhythmias and Treatments
- Cardiac pacing and defibrillation studies
- Atrial Fibrillation Management and Outcomes
- Cardiac electrophysiology and arrhythmias
- Cardiovascular Issues in Pregnancy
- Cardiomyopathy and Myosin Studies
- Cardiovascular and Diving-Related Complications
- Cardiovascular Function and Risk Factors
- Electrostatic Discharge in Electronics
- Neuroscience and Neural Engineering
- Cardiovascular Syncope and Autonomic Disorders
- Cardiac Structural Anomalies and Repair
- Microbial Inactivation Methods
- Neurogenetic and Muscular Disorders Research
- Venous Thromboembolism Diagnosis and Management
- Cardiovascular Effects of Exercise
- Cardiac Valve Diseases and Treatments
- Cardiac Imaging and Diagnostics
- Analytical Chemistry and Chromatography
- Toxin Mechanisms and Immunotoxins
- Neurological disorders and treatments
- Muscle activation and electromyography studies
- ECG Monitoring and Analysis
- Analytical Methods in Pharmaceuticals
- Congenital Heart Disease Studies
Mayo Clinic in Arizona
2015-2024
Mayo Clinic
2013-2024
Mayo Clinic Health System
2021-2024
Smt. Kashibai Navale Medical College and General hospital
2023
Mayo Clinic in Florida
2013-2022
WinnMed
2013-2021
E Ink (South Korea)
2020
Rosalind Franklin University of Medicine and Science
2018
Stanford University
2017
University of Washington
2017
Background The prognosis of left ventricular noncompaction (LVNC) remains elusive despite its recognition as a clinical entity for >30 years. We sought to identify and imaging characteristics risk factors mortality in patients with LVNC. Methods Results 339 adults LVNC seen between 2000 2016 were identified. was defined end-systolic noncompacted compacted myocardial ratio >2 (Jenni criteria) end-diastolic trough trabeculation-to-epicardium (X):peak (Y) <0.5 (Chin by echocardiography;...
A patent foramen ovale (PFO) may permit arterial embolization of thrombi that accumulate on the leads cardiac implantable electronic devices in right-sided chambers. We sought to determine whether a PFO increases risk stroke/transient ischemic attack (TIA) patients with endocardial leads.We retrospectively evaluated all who had implanted between January 1, 2000, and October 25, 2010, at Mayo Clinic Rochester. Echocardiography was used establish definite non-PFO cohorts. The primary end point...
Background: Reentrant ventricular arrhythmias are a major cause of sudden death in patients with structural heart disease. Current treatments focus on electrically homogenizing regions scar contributing to arrhythmia ablation or altering conductive properties using antiarrhythmic drugs. The high conductivity carbon nanotubes may allow restoration conduction where impaired electrical results functional abnormalities. We propose new concept for treatment stretchable, flexible biopatch attempt...
BackgroundThe outcomes of left bundle branch pacing (LBBP) and ventricular septal (LVSP) in patients with heart failure remain to be learned.ObjectiveThe objective this study was assess the echocardiographic clinical LBBP, LVSP, deep (DSP).MethodsThis retrospective included who met criteria for cardiac resynchronization therapy (CRT) underwent attempted LBBP 5 Mayo centers. Clinical, electrocardiographic, data were collected at baseline follow-up.ResultsA total 91 consecutive study. 52 had...
Bileaflet mitral valve prolapse (biMVP) is associated with frequent ventricular ectopy (VE) and malignant arrhythmia. We examined the effect of (MV) surgery on VE burden in biMVP patients.We included 32 consecutive patients undergoing MV for regurgitation secondary to between 1993 2012 at Mayo Clinic who had available pre- post-operative Holter monitoring data. Characteristics a significant reduction postoperative (group A, defined as >10% compared baseline) were rest study B).In overall...
Current thermal ablation methods for atrial fibrillation, including radiofrequency and cryoablation, have a suboptimal success rate. To avoid pulmonary vein (PV) stenosis, is performed outside of the PV, despite importance triggers inside vein. We previously reported on acute effects novel direct current electroporation approach with balloon catheter to create lesions
An increasing number of catheter ablations involve the mitral annular region and valve apparatus, risk interaction with (MV) complex. We review our experience ablation-related MV injury resulting in severe regurgitation (MR) to delineate mechanisms outcomes.We searched Mayo Clinic surgical database over a 19-year period (1993-2012) electrophysiologic procedures 23-year (1990-2013) identified 9 patients ablation related requiring clinical intervention.Indications for included atrial...
Cardiac implantable electronic devices (CIEDs) are commonly associated with transvenous lead-related thrombi that can cause pulmonary embolism (PE). We retrospectively evaluated all patients CIED leads implanted at Mayo Clinic Rochester between 1 January 2000, and 25 October 2010. Pulmonary outcomes during follow-up were screened using diagnosis codes confirmed imaging study reports. Of 5646 (age 67.3 ± 16.3 years, 64% men, mean 4.69 years) 88 developed PE (1.6%), incidence 3.32 [95%...
Arrhythmogenic Substrate of Ventricular Arrhythmias at the AMC Introduction Catheter ablation ventricular arrhythmia (VA) fibrous aortic mitral continuity (AMC) has been described, yet nature arrhythmogenic substrate remains unknown. Methods Procedural records 528 consecutive patients undergoing VA Mayo Clinic, Rochester, MN, were reviewed. The electrocardiographic and electrophysiologic characteristics with successful analyzed to characterize underlying substrate. Results Of 21 (mean age...
Leadless cardiac pacing (LCP) has emerged as a new modality for permanent pacing. We sought to describe comparative outcomes between LCP and transvenous pacemakers.Patients receiving (Micra [Medtronic, Minneapolis, MN, USA] Nanostim [St. Jude Medical/Abbott Laboratories, Chicago, IL, USA]) 2014 2017 at the Mayo Clinic Heart Rhythm Enterprise practice (Rochester, USA; Jacksonville, FL, Scottsdale, AZ, USA) were identified. identified 1:1 age- sex-matched controls single-chamber ventricular...
Introduction The application of brief high voltage electrical pulses to tissue can lead an irreversible or reversible electroporation effect in a cell-specific manner. In the management ventricular arrhythmias, ability target different types, specifically cardiac conduction (His-Purkinje System) vs. myocardium would be advantageous. We hypothesize that pulsed electric fields (PEFs) applied safely beating heart through catheter-based approach, and we tested whether superficial Purkinje cells...
Mitral annular disjunction (MAD) has recently been recognized as an arrhythmogenic entity. Data on the electrophysiological substrate well outcomes of catheter ablation ventricular arrhythmias in patients with MAD is limited.Forty (mean age 47±15 years; 70% female) underwent for arrhythmias. Detailed clinical, electrocardiographic, cardiac imaging, and procedural data were collected. Clinical compared between who had modification area those did not.Twenty-three (57.5%) premature...