A5077181880- Cardiomyopathy and Myosin Studies
- Cardiovascular Effects of Exercise
- Cardiac electrophysiology and arrhythmias
- Cardiac Arrhythmias and Treatments
- Atrial Fibrillation Management and Outcomes
- Cardiovascular Function and Risk Factors
- Cardiac pacing and defibrillation studies
- Cardiac Valve Diseases and Treatments
- Cardiac Imaging and Diagnostics
- Viral Infections and Immunology Research
- Obstructive Sleep Apnea Research
- Sarcoidosis and Beryllium Toxicity Research
- Cardiac Structural Anomalies and Repair
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Congenital Heart Disease Studies
- Neuroscience of respiration and sleep
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Cardiac Arrest and Resuscitation
- COVID-19 Clinical Research Studies
- Epilepsy research and treatment
- Cardiovascular Disease and Adiposity
- Long-Term Effects of COVID-19
- Heart Rate Variability and Autonomic Control
- Vasculitis and related conditions
- Heart Failure Treatment and Management
Mayo Clinic
2016-2025
British Heart Foundation
2022-2025
Mayo Clinic in Arizona
2016-2025
Barts Health NHS Trust
2019-2025
WellSpan Health
2021-2025
Mayo Clinic in Florida
2017-2025
William Harvey Research Institute
2020-2025
Queen Mary University of London
2020-2025
St Bartholomew's Hospital
2020-2025
University of Birmingham
2025
Early studies suggest that coronavirus disease 2019 (COVID-19) is associated with a high incidence of cardiac arrhythmias. Severe acute respiratory syndrome 2 infection may cause injury to myocytes and increase arrhythmia risk.The purpose this study was evaluate the risk arrest arrhythmias including incident atrial fibrillation (AF), bradyarrhythmias, nonsustained ventricular tachycardia (NSVT) in large urban population hospitalized for COVID-19. We also evaluated correlations between...
Excessive daytime sleepiness (EDS), a common symptom among patients with sleep-disordered breathing, is closely associated the development of cardiovascular diseases, but its long-term prognostic value not completely understood. The aim this study was to investigate whether EDS would be an independent factor after myocardial infarction.We prospectively recruited 112 post-myocardial infarction patients. Epworth Sleepiness Scale completed before polysomnography, and defined as score ≥11. After...
Arrhythmogenic cardiomyopathy (ACM) is a primary disease of the myocardium, predominantly caused by genetic defects in proteins cardiac intercalated disc, particularly, desmosomes. Transmission mostly autosomal dominant with incomplete penetrance. ACM also has wide phenotype variability, ranging from premature ventricular contractions to sudden death and heart failure. Among other drivers modulators phenotype, inflammation response viral infection immune triggers have been postulated be an...
Background: There is a paucity of data regarding the phenotype dilated cardiomyopathy (DCM) gene variants in general population. We aimed to determine frequency and penetrance DCM-associated putative pathogenic adult population, with focus on expression clinical subclinical phenotype, including structural, functional, arrhythmic disease features. Methods: UK Biobank participants who had undergone whole exome sequencing, ECG, cardiovascular magnetic resonance imaging were selected for study....
Out of hospital cardiac arrest (OHCA) outcomes can be improved by strengthened the chain survival, namely prompt cardiopulmonary resuscitation (CPR) and automated external defibrillator (AED). However, provision bystander CPR AED use remains low due to individual patient factors ranging from lack education socioeconomic barriers resources such as limited availability AEDs in community. Although impact health inequalities on survival OHCA is documented, it imperative that we identify...
Injury by contaminated sharp instruments and needles constitutes a major occupational hazard for healthcare workers. In confidential survey at district general hospital, 300 professionals were asked about their personal experience of needle-stick injury attitudes to reporting. 279 individuals responded, whom 38% had experienced least one (mean 1.8) in the past year 74% sustained such an during careers 3.0). Although 80% respondents aware that incidents should be notified, only 51% those...
Background Obstructive sleep apnea ( OSA ) is an important risk factor for the development of cardiovascular diseases including myocardial infarction MI ). The aim this study was to investigate effects on prognosis after , and determine which specific measures severity best predicted outcomes. Methods Results We performed a prospective study, in 112 patients without prior diagnosis underwent comprehensive polysomnography within median 7 days . Patients were followed up at 6‐monthly intervals...
Abstract Background As the availability of genomic testing grows, variant interpretation will increasingly be performed by generalists, rather than domain-specific experts. Demand is rising for laboratories to accurately classify variants in inherited cardiac condition (ICC) genes, including secondary findings. Methods We analyse evidence inheritance patterns, allelic requirement, disease mechanism and disease-relevant classes 65 ClinGen-curated ICC gene-disease pairs. present this...