- Cardiomyopathy and Myosin Studies
- Congenital Heart Disease Studies
- Cardiovascular Function and Risk Factors
- Blood Pressure and Hypertension Studies
- Neuroscience of respiration and sleep
- Cardiac Structural Anomalies and Repair
- Children's Physical and Motor Development
- Cardiovascular Syncope and Autonomic Disorders
- Obstructive Sleep Apnea Research
- Cardiac Arrhythmias and Treatments
- Pancreatic and Hepatic Oncology Research
- Spaceflight effects on biology
- Heart rate and cardiovascular health
- Dietary Effects on Health
- Diet and metabolism studies
- Eating Disorders and Behaviors
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Cardiac electrophysiology and arrhythmias
- Gallbladder and Bile Duct Disorders
- Cardiovascular Health and Disease Prevention
- Glycogen Storage Diseases and Myoclonus
- Schizophrenia research and treatment
- Sleep and Wakefulness Research
- Vascular Procedures and Complications
- Cardiac pacing and defibrillation studies
William Harvey Research Institute
2023-2025
Queen Mary University of London
2025
Mayo Clinic in Arizona
2020-2025
Mayo Clinic
2020-2024
King Abdulaziz University
2024
WinnMed
2020-2022
Mayo Clinic in Florida
2020
University of Manchester
2018
Manchester University
2018
Extremely low diastolic blood pressure has been reported to be associated with increased adverse cardiovascular events (ie, the J-shape phenomenon); however, current US guidelines recommend an intensive target of less than 130/80 mm Hg without mentioning lower limits pressure.
Cancer frequently develops resistance to the majority of chemotherapy treatments.This study aimed examine synergistic cytotoxic and antitumor effects SGLT2 inhibitors, specifically Canagliflozin (CAN), Dapagliflozin (DAP), Empagliflozin (EMP), Doxorubicin (DOX), using in vitro experimentation.The precise combination CAN+DOX has been found greatly enhance doxorubicin (DOX) MCF-7 cells.Interestingly, it was shown that cancer cells exhibit an increased demand for glucose ATP order support their...
HomeCirculation: Cardiovascular InterventionsVol. 11, No. 7Novel Distal Left Radial Artery Access in Anatomical Snuffbox for Recanalization of Proximal Total Occlusion and Percutaneous Coronary Intervention Through Internal Mammary Free AccessCase ReportPDF/EPUBAboutView PDFView EPUBSections ToolsAdd to favoritesDownload citationsTrack citationsPermissionsDownload Articles + Supplements ShareShare onFacebookTwitterLinked InMendeleyReddit Jump toSupplementary MaterialsFree ReportPDF/EPUBNovel...
Aims Endoscopic ultrasound-guided fine-needle biopsy (EUS-FNB) is a technique used for tissue acquisition providing the higher diagnostic accuracy solid pancreatic and gastrointestinal lesions. Rapid onsite evaluation (ROSE) us eful firsthand technique. Because of its expensive technical requirement, macroscopic (MOSE) desired method to assess visual characteristics/features sample/specimen positive hist opathological output. However, adequate size requirement. What should we have...
Background: Sleep disordered breathing (SDB) is frequently observed in patients with cardiovascular disease, and associated intermittent hypoxia, sympathetic activation, oxidative stress, endothelial dysfunction, all of which may facilitate the development progression disease. Objectives: We sought to determine prevalence, subtypes, clinical implications comorbid SDB hypertrophic cardiomyopathy (HCM). Methods: In this prospective observational study, HCM without prior diagnosis were...
Abstract Introduction Cardiopulmonary exercise testing (CPET) has an established role in the clinical evaluation of intolerance and risk stratification patients with heart failure. There is limited data assessing its prognostic utility Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC). The predisposition ARVC for ventricular arrhythmias sudden cardiac death led to recommendations restrictions limits our understanding how impairment oxygen extraction output impact disease progression...
Introduction: During sixth decade of this century Beta adrenoceptor antagonists were developed for the treatment cardiac arrhythmias and angina pectoris. It was discovered later on that long term with beta blockers caused decrease in arterial blood pressure. adrenergic blocking drugs can be characterized by their pharmacokinetic properties. One property is lipophilic or hydrophilic. Bisoprolol takes an intermediate position between hydrophilic properties blockers. readily Conclusion: This...
<h3>Background</h3> Hypertrophic cardiomyopathy (HCM) represents the most common inherited characterized by otherwise unexplained left ventricular hypertrophy. Sleep disordered breathing (SDB) (including both central and obstructive sleep apnea) is considered to be an important potentially reversible cause of cardiovascular disease progression. This prospective trial aims define prevalence SDB within patients diagnosed with HCM using gold standard polysomnography (PSG). Previous studies have...
<h3>Background</h3> Hypertrophic cardiomyopathy (HCM) and obstructive sleep apnoea (OSA) are independently associated with increased risk of arrhythmic events. Oximetry based studies suggest a high prevalence OSA in HCM. Signal Average ECG (SAECG) is non-invasive method detecting late ventricular potentials which low-amplitude, high-frequency signals occurring the terminal portion QRS complex, analysis may aid predicting reentry arrhythmias sudden cardiac death. SAECG parameter profiles HCM...