A5057065254- Heart Failure Treatment and Management
- Telemedicine and Telehealth Implementation
- COVID-19 and healthcare impacts
- Health Systems, Economic Evaluations, Quality of Life
- Venous Thromboembolism Diagnosis and Management
- Pharmaceutical Practices and Patient Outcomes
- Lipoproteins and Cardiovascular Health
- Mobile Health and mHealth Applications
- Chemotherapy-induced cardiotoxicity and mitigation
- Cardiac Health and Mental Health
- Cardiovascular Function and Risk Factors
- Healthcare Systems and Technology
- Cardiac Valve Diseases and Treatments
- Cardiac Imaging and Diagnostics
- Diversity and Career in Medicine
- Cardiac, Anesthesia and Surgical Outcomes
- Pharmaceutical Economics and Policy
- Primary Care and Health Outcomes
- Cardiovascular Health and Risk Factors
- COVID-19 Clinical Research Studies
- Pulmonary Hypertension Research and Treatments
- Blood Pressure and Hypertension Studies
- Cardiac Structural Anomalies and Repair
- Clinical practice guidelines implementation
- Atrial Fibrillation Management and Outcomes
University of Pennsylvania
2016-2025
CVS Health (United States)
2022-2025
Hospital of the University of Pennsylvania
2017-2023
College of the Holy Cross
2023
Penn Center for AIDS Research
2020-2023
Southwestern Medical Center
2023
The University of Texas Southwestern Medical Center
2023
University of Pennsylvania Health System
2020-2022
Office of Chief Medical Examiner
2020-2022
Philadelphia VA Medical Center
2022
The coronavirus disease 2019 (COVID-19) pandemic has required a shift in health care delivery platforms, necessitating new reliance on telemedicine.To evaluate whether inequities are present telemedicine use and video visit for visits during the COVID-19 pandemic.In this cohort study, retrospective medical record review was conducted from March 16 to May 11, 2020, of all patients scheduled primary specialty ambulatory clinics at large academic system. Age, race/ethnicity, sex, language,...
Early studies suggest that coronavirus disease 2019 (COVID-19) is associated with a high incidence of cardiac arrhythmias. Severe acute respiratory syndrome 2 infection may cause injury to myocytes and increase arrhythmia risk.The purpose this study was evaluate the risk arrest arrhythmias including incident atrial fibrillation (AF), bradyarrhythmias, nonsustained ventricular tachycardia (NSVT) in large urban population hospitalized for COVID-19. We also evaluated correlations between...
<h3>Importance</h3> Sodium-glucose cotransporter 2 (SGLT2) inhibitors significantly reduce deaths from cardiovascular conditions, hospitalizations for heart failure, and progression of kidney disease among patients with type diabetes. Black individuals have a disproportionate burden chronic (CKD). Adoption novel therapeutics has been slower female low socioeconomic status than White or male higher status. <h3>Objective</h3> To assess whether inequities based on race/ethnicity, gender, exist...
Randomized clinical trials have shown that glucagon-like peptide-1 receptor agonists (GLP-1 RAs) cause significant weight loss and reduce cardiovascular events in patients with type 2 diabetes (T2D). Black a disproportionate burden of obesity disease higher rate cardiovascular-related mortality. Racial ethnic disparities health outcomes are largely attributable to the pervasiveness structural racism, who marginalized by racism less access novel therapeutics.To evaluate GLP-1 RA uptake among...
Background Regular physical activity reduces the risk of cardiovascular events, but most ischemic heart disease ( IHD ) patients do not obtain enough. Methods and Results ACTIVE REWARD (A Clinical Trial Investigating Effects a Randomized Evaluation Wearable Activity Trackers with Financial Rewards) was 24‐week home‐based, remotely monitored, randomized trial 16‐week intervention (8‐week ramp‐up incentive phase 8‐week maintenance phase) an follow‐up. Patients used wearable devices to track...
Background: Beginning in 2012, direct oral anticoagulants (DOACs) were approved for treatment and prevention of venous thromboembolism. Prior investigations have demonstrated slow rates adoption novel therapeutics black patients. We assessed the association racial/ethnic socioeconomic factors with DOAC use among commercially insured thromboembolism Methods Results: performed a retrospective cohort analysis adult patients an incident diagnosis between January 2010 December 2016 using...
Statins reduce the risk of major adverse cardiovascular events, but less than one-half individuals in America who meet guideline criteria for a statin are actively prescribed this medication.To evaluate whether nudges to clinicians, patients, or both increase initiation prescribing during primary care visits.This cluster randomized clinical trial evaluated 158 clinicians from 28 practices including 4131 patients. The design included 12-month preintervention period and 6-month intervention...
This quality improvement study assesses referral rates for cardiac rehabilitation after a default opt-out option is added to the decision pathway in electronic medical record.
<h3>Importance</h3> Statin therapy is underused for many patients who could benefit. <h3>Objective</h3> To evaluate the effect of passive choice and active interventions in electronic health record (EHR) to promote guideline-directed statin therapy. <h3>Design, Setting, Participants</h3> Three-arm randomized clinical trial with a 6-month preintervention period intervention. Randomization conducted at cardiologist level 16 cardiology practices Pennsylvania New Jersey. The study included 82...
Despite statins' benefit in preventing major adverse cardiovascular events, most patients with an indication for statin therapy are not appropriately treated. Clinicians' limited time and lack of systematic efforts to address preventive care likely contribute gaps prescribing. To determine the effect on prescribing 2 interventions refer appropriate a pharmacist lipid management. These pragmatic cluster randomized clinical trials were conducted among 12 total primary practices community...
Catheter-directed thrombolysis (CDT) and systemic (ST) are used to treat intermediate/high-risk pulmonary embolism (PE) in the absence of comparative safety effectiveness data. We utilized a large administrative database perform analysis catheter-directed versus thrombolysis. From Optum ® Clinformatics Data Mart private-payer insurance claims database, we identified 100,744 patients hospitalized with PE between 2004 2014. extracted demographic characteristics, high-risk features, components...
Background Current atherosclerotic cardiovascular disease (ASCVD) predictive models have limitations; thus, efforts are underway to improve the discriminatory power of ASCVD models. Objective We sought evaluate social media posts predict 10-year risk for as compared that pooled cohort equations (PCEs). Methods consented patients receiving care in an urban academic emergency department share access their Facebook and electronic medical records (EMRs). retrieved status updates up 5 years prior...
Background PCSK9 (proprotein convertase subtilisin/kexin type 9) inhibitors represent a promising class of lipid-lowering therapy, although their use has been limited by cost concerns. Methods and Results A retrospective cohort study was conducted using nationwide commercial claims database comprising patients with atherosclerotic cardiovascular disease (ASCVD), aged 18 to 64 years. We identified the number ASCVD started on inhibitor from dates US Food Drug Administration approval in quarter...
Objective: To understand how differences in primary care appointment completion rates between Black and non-Black patients changed 2020 within the context of COVID-19 pandemic when telemedicine utilization peaked. Materials Methods: We conducted a retrospective cohort study using electronic health record from January 1 to December 31, 2020, among all adults scheduled for large academic medical center. used mixed-effects logistic regression estimate adjusted compared with those as 2019 four...