A5023850643- Cardiac Arrhythmias and Treatments
- Atrial Fibrillation Management and Outcomes
- Cardiac pacing and defibrillation studies
- Cardiac electrophysiology and arrhythmias
- Cardiac Imaging and Diagnostics
- Cardiomyopathy and Myosin Studies
- Advanced MRI Techniques and Applications
- Cardiovascular Syncope and Autonomic Disorders
- Cardiac tumors and thrombi
- Cardiovascular Effects of Exercise
- Cardiovascular Function and Risk Factors
- Heart Rate Variability and Autonomic Control
- ECG Monitoring and Analysis
- Cardiac Valve Diseases and Treatments
- Cardiac Structural Anomalies and Repair
- Pain Management and Treatment
- Pericarditis and Cardiac Tamponade
- Neurological disorders and treatments
- Sarcoidosis and Beryllium Toxicity Research
- Cardiovascular Issues in Pregnancy
- Viral Infections and Immunology Research
- Aortic Disease and Treatment Approaches
- Cardiovascular Disease and Adiposity
- Infective Endocarditis Diagnosis and Management
- Acute Myocardial Infarction Research
Mayo Clinic
2020-2025
Mayo Clinic in Arizona
2020-2024
WinnMed
2020-2024
Mayo Clinic Hospital
2023
Mayo Clinic in Florida
2022
University of Connecticut
2013-2021
Virginia Commonwealth University
2017-2021
University of Vermont
2021
Lamar University
2020
University Health System
2018
Abstract Ventricular electrical storm (VES) is a clinical scenario characterized by the clustering of multiple episodes sustained ventricular arrhythmias (VA) over short duration. Patients with VES are prone to psychological disorders, heart failure decompensation, and increased mortality. Studies have shown that 10–28% patients secondary prevention ICDs can sustain VES. The triad susceptible electrophysiologic substrate, triggers, autonomic dysregulation govern pathogenesis rate VA,...
Cardiovascular disease (CVD) is a major contributor to longterm mortality after liver transplantation (LT) necessitating aggressive modification of CVD risk. However, it unclear how coronary artery (CAD) and the development dyslipidemia following LT impacts clinical outcomes management these factors may impact survival. Patients undergoing at Virginia Commonwealth University from January 2007 2017 were included (n = 495). CAD risk in all potential recipients (LTRs) over age 50 years...
BACKGROUND: Power-controlled radiofrequency ablation with irrigated-tip catheters has been the norm for ventricular almost 2 decades. New catheter technology recently integrated more accurate tissue temperature sensing enabling temperature-controlled irrigated ablation. We aimed to investigate in vivo parameters and lesion formation characteristics myocardium using a novel catheter. METHODS: Twenty canines were divided into 3 groups: 4 noninfarcted, acute (phase I); 8 chronic II); infarcted,...
ABSTRACT Background Mitral annular disjunction (MAD) carries an increased risk of complex ventricular arrhythmias, which can lead to sudden cardiac death. Many these patients undergo implantable cardioverter defibrillator (ICD) implantation, but their ICD outcomes are not known. Objective The aim this study was assess the implantation and predictors appropriate therapies in with MAD. Methods included MAD who underwent implantation. Clinical, electrocardiographic, imaging, device therapy data...
Heart block requiring permanent pacemaker (PPM) implantation is a relatively frequent complication of transcatheter aortic valve replacement (TAVR).The purpose this study was to perform contemporary meta-analysis provide an updated assessment clinically useful predictors PPM post-TAVR.Medline and EMBASE searches were performed include all studies reporting post-TAVR between 2015 2020. Pertinent data extracted from the for further analysis. RevMan used create forest plots calculate risk...
Unfortunately, some patients with long QT syndrome (LQTS) experience breakthrough cardiac events (BCEs) despite maximal therapy. Small studies have shown that refractory LQTS cases may benefit from intentional permanent atrial pacing (IPAP). As such, we sought to determine the genotype-specific utilization and efficacy of IPAP in a single-center registry.In this retrospective study, electronic medical records 1065 diagnosed were used identify individuals received IPAP. Pre- post-IPAP heart...
The MicraTM transcatheter pacing system (TPS) (Medtronic) is the only leadless pacemaker that promotes atrioventricular (AV) synchrony via accelerometer-based atrial sensing. Data regarding real-world experience with this novel are scarce. We sought to characterize patients undergoing -AV implants, describe percentage AV achieved, and analyze causes for suboptimal synchrony.In retrospective cohort study, electronic medical records from 56 consecutive implants at Mayo Clinic sites in...
Cardiac sarcoidosis (CS) is a nonischemic cardiomyopathy (NICM) characterized by infiltration of noncaseating granulomas involving the heart with highly variable clinical manifestations that can include conduction abnormalities and systolic failure. resynchronization therapy (CRT) has shown significant promise in NICM, though little known about its efficacy patients CS.To determine if CRT improved cardiac remodeling CS.We retrospectively reviewed all or histological diagnosis CS who...
Frequent premature ventricular contractions (PVCs) can cause cardiomyopathy (CM). Postextrasystolic potentiation (PESP) and irregularity have been in implicated as triggers of PVC-CM. Because both phenomena also be found atrial (PACs), it is speculated that frequent PACs similar consequences.A single-center, retrospective study included all consecutive patients undergoing a 14-day Holter monitors (November 2014 to October 2016). Patients were divided into four groups by ectopy burden group 1...
High premature ventricular contractions (PVCs) burden does not always predict the development of PVC-cardiomyopathy (CM). We sought to evaluate post-extrasystolic potentiation (PESP) left ejection fraction (LVEF) severity PVC-CM in an animal model.
BackgroundTachycardia and heart rate irregularity are proposed triggers of premature ventricular contraction–induced cardiomyopathy (PVC-cardiomyopathy). Bigeminal atrial contractions (PACs PVCs) increase result in rhythm irregularities but differ their effects on synchrony. Comparing chronic bigeminal PACs with PVCs would provide insights into mechanisms PVC-cardiomyopathy.ObjectiveTo compare the impact hemodynamics, structure, function.MethodsPacemakers were implanted 27 canines to...
Abstract Background Atrial fibrillation (AF) is relatively less frequent in younger patients (age < 50). Recently, studies have suggested that early restoration of sinus rhythm may lead to improved outcomes compared with rate control, however the efficacy catheter ablation for AF young scarce. Methods We included all hospitalized between 18 and 50 years a diagnosis from Nationwide Readmission Database 2016–2017 Healthcare Cost Utilization Project. Demographic comorbidity data were...
Strain imaging has been suggested as a tool to detect early left ventricular (LV) dysfunction due frequent premature contractions (PVCs) in patients with preserved LV ejection fraction (EF). However, the progression of intraventricular dyssynchrony (IVD), radial, and circumferential strain (RS, CS) PVC-cardiomyopathy (CM) are unknown. The aim this study was elucidate patterns CS, IVD, electro-mechanical latency (EML) PVC-CM. Pacemakers were implanted 20 canines reproduce bigeminy at 200ms...