A5014887952- Cardiac Arrhythmias and Treatments
- Cardiac electrophysiology and arrhythmias
- Cardiac pacing and defibrillation studies
- Atrial Fibrillation Management and Outcomes
- ECG Monitoring and Analysis
- Microbial Inactivation Methods
- Cardiomyopathy and Myosin Studies
- Electrostatic Discharge in Electronics
- Cardiovascular Effects of Exercise
- Cardiovascular Function and Risk Factors
- Ion channel regulation and function
- Venous Thromboembolism Diagnosis and Management
- Toxin Mechanisms and Immunotoxins
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Neuroscience and Neural Engineering
- Heart Rate Variability and Autonomic Control
- Cardiac Imaging and Diagnostics
- Sarcoidosis and Beryllium Toxicity Research
- Pericarditis and Cardiac Tamponade
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Tissue Engineering and Regenerative Medicine
- Pain Management and Treatment
- 3D Printing in Biomedical Research
- Congenital Heart Disease Studies
- Phonocardiography and Auscultation Techniques
Mayo Clinic
2015-2025
WinnMed
2015-2025
Hospital of the University of Pennsylvania
2021-2025
Mayo Clinic in Arizona
2015-2024
Mayo Clinic Hospital
2024
University of Pennsylvania
2021-2023
Mayo Clinic in Florida
2015-2022
Jacksonville College
2022
Amsterdam UMC Location University of Amsterdam
2019
Ben-Gurion University of the Negev
2016-2017
Background: Reentrant ventricular arrhythmias are a major cause of sudden death in patients with structural heart disease. Current treatments focus on electrically homogenizing regions scar contributing to arrhythmia ablation or altering conductive properties using antiarrhythmic drugs. The high conductivity carbon nanotubes may allow restoration conduction where impaired electrical results functional abnormalities. We propose new concept for treatment stretchable, flexible biopatch attempt...
Background The Purkinje network appears to play a pivotal role in the triggering as well maintenance of ventricular fibrillation. Irreversible electroporation ( IRE ) using direct current has shown promise nonthermal ablation modality heart, but its ability target and ablate tissue is undefined. Our aim was investigate potential for selective Purkinje/fascicular fibers . Methods Results In an ex vivo Langendorff model canine heart (n=8), delivered unipolar manner at various dosages from 750...
Current thermal ablation methods for atrial fibrillation, including radiofrequency and cryoablation, have a suboptimal success rate. To avoid pulmonary vein (PV) stenosis, is performed outside of the PV, despite importance triggers inside vein. We previously reported on acute effects novel direct current electroporation approach with balloon catheter to create lesions
Background: Right ventricular systolic dysfunction (RVD) often coexists with various cardiopulmonary diseases. However, the association between RVD and risk of sudden cardiac death (SCD) has not been well studied. This study examined SCD associated in patients heterogeneous underlying Methods: The Mayo Clinic care unit database included 5463 consecutive complete echocardiographic evaluation to assess right function severity. Prospective surveillance follow-up was obtained for all patients....
Dofetilide is an effective antiarrhythmic medication for rhythm control in atrial fibrillation, but carries a significant risk of pro-arrhythmia and requires meticulous dosing monitoring. The cornerstone this monitoring, measurement the QT/QTc interval, imperfect surrogate plasma concentration, efficacy, pro-arrhythmic potential.The aim our study was to test application deep learning approach (using convolutional neural network) assess morphological changes on surface ECG (beyond QT...
Abstract Background Endocardial radiofrequency ablation of epicardial ganglionic plexus (GP) for atrial fibrillation (AF) is complicated by myocardial damage. Objectives We hypothesized that an approach with a novel nitinol catheter system capable causing irreversible electroporation (IRE) direct current (DC) could selectively and permanently destroy GP without collateral injury. Methods Acute studies medium‐term terminal (mean survival, 1137 days) were performed seven dogs. In the acute...