- Sarcoidosis and Beryllium Toxicity Research
- Cardiovascular Issues in Pregnancy
- Heart Failure Treatment and Management
- Cardiovascular Function and Risk Factors
- Cardiac Structural Anomalies and Repair
- Palliative Care and End-of-Life Issues
- Cardiac Valve Diseases and Treatments
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Family and Patient Care in Intensive Care Units
- Pulmonary Hypertension Research and Treatments
- Infective Endocarditis Diagnosis and Management
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Cardiac Arrhythmias and Treatments
- Cardiac pacing and defibrillation studies
- Cardiac Imaging and Diagnostics
- Vasculitis and related conditions
- Cardiac electrophysiology and arrhythmias
- Atrial Fibrillation Management and Outcomes
- Viral Infections and Immunology Research
- S100 Proteins and Annexins
- Congenital heart defects research
- Infectious Diseases and Tuberculosis
- Healthcare Decision-Making and Restraints
- Parathyroid Disorders and Treatments
- Peripheral Neuropathies and Disorders
Mayo Clinic in Arizona
2016-2025
Duke University
2025
Mayo Clinic
2016-2024
Cliniques Universitaires Saint-Luc
2023
Agostino Gemelli University Polyclinic
2023
WinnMed
2016-2022
Mayo Clinic in Florida
2021-2022
University of Nebraska Medical Center
2014
Objective Malondialdehyde‐acetaldehyde (MAA) adducts are a product of oxidative stress associated with tolerance loss in several disease states. This study was undertaken to investigate the presence MAA and circulating anti‐MAA antibodies patients rheumatoid arthritis (RA). Methods Synovial tissue from RA osteoarthritis (OA) were examined for MAA‐modified citrullinated proteins. Anti‐MAA antibody isotypes measured (n = 1,720) healthy controls 80) by enzyme‐linked immunosorbent assay....
<h3>Importance</h3> Spontaneous coronary artery dissection (SCAD) is a notable cause of acute syndrome in women childbearing age. <h3>Objective</h3> To test the hypothesis that pregnancy after SCAD associated with recurrent SCAD. <h3>Design, Setting, and Participants</h3> Three study designs were implemented: case series SCAD; nested case-control comparing patients to matched controls without cohort study. Women who potential enrolled into Mayo Clinic Registry from August 30, 2011, April 4,...
The 22q11.2 chromosome deletion syndrome occurs at a frequency of 1 in 4000 live births. Fluorescent situ hybridization is reliable means testing for this genetic abnormality.To describe the otolaryngologic manifestations to improve recognition and management these disorders.A retrospective medical record review 102 patients with 22q 11.2 deletions confirmed by fluorescent hybridization.A multidisciplinary clinic an academic children's hospital.All problems were recorded, including facial...
Cardiomyopathy is a leading cause of pregnancy-related mortality and the number one death in late postpartum period. Delay diagnosis associated with severe adverse outcomes.
Background: The aims of this study are to evaluate the rate progression preclinical (Stage A and B) heart failure, identify associated characteristics, long-term outcomes. Methods: Retrospective review Olmsted County Heart Function Study. Individuals categorized as Stage or B failure at initial visit that returned for a second 4 years later were included. Logistic regression analyses evaluated group differences with adjustment age sex. Results: At 1, 413 (32%) individuals classified B. By 2,...
Background A high prevalence of preclinical heart failure (HF) (Stages and B) has previously been shown. The aim this study was to explore factors associated with the incidence HF in a community population. Methods Results Retrospective review 393 healthy individuals aged ≥45 years from Olmsted County Heart Function Study that returned for 2 visits, 4 apart. At visit 2, remained normal were compared those developed HF. By second visit, 191 (49%) (12.1 cases per 100 person-years follow-up);...
Severe tricuspid regurgitation (TR) is associated with considerable morbidity/mortality in an elderly population multiple comorbidities. There interest transcatheter interventions to manage severe TR. Understanding complex right heart (RH) geometry and valve shape size has implications for patient/device selection intervention. We characterized RH anatomy by computed tomography patients symptomatic TR considered intervention.The retrospective Mayo Clinic study included 29 echocardiogram...
Women with congenital heart disease (CHD) are at risk of pregnancy-related adverse outcomes (PRAO). The purpose this study was to assess temporal changes in cardiac structure and function (cardiac remodelling) during pregnancy, the association PRAO women CHD.
Abstract Cardiomyopathy occurring during pregnancy or postpartum represents a leading cause of maternal mortality. An overlap between pregnancy-associated symptoms and cardiomyopathy contributes to delays in diagnosis. To address the need for screening improve diagnosis pregnancy-related cardiomyopathy, we sought evaluate association cardiovascular symptoms, an adapted version 12-item Kansas City Questionnaire (KCCQ-P) left ventricular systolic dysfunction (LVSD). We conducted single-arm...
Introduction: Cardiac sarcoidosis (CS) often results in systolic heart failure (HF) and responds favorably to guideline directed medical therapy (GDMT). A multidisciplinary team approach HF care is recommended but few published examples exist CS patients. Methods: We queried an institutional registry of 599 patients (2000-2023) for with index LVEF < 50% (within 90 d evaluation) follow-up TTE within 11-36 months. In our medication management (MTM) program (started 1/8/2019), pharmacists...
Background A multidisciplinary approach improves guideline‐directed medical therapy (GDMT) in systolic heart failure (HF), but its efficacy patients with HF due to cardiac sarcoidosis (CS) is unreported. Methods and Results In a retrospective cohort study, we reviewed 848 from our institutional CS clinics, identifying those diagnosis, (LVEF < 50%) at index evaluation, echocardiograms within 90 days 11‐36 months. Patients were stratified by participation pharmacist‐led medication...
Background: Syncope is a common presenting complaint in the outpatient setting and requires thoughtful meticulous approach to history-taking skills. This crucial discerning cardiac versus non-cardiac etiologies, underscoring pivotal role of healthcare professionals diagnostic process. Case Report: case 76-year-old male who presented primary care clinic following an episode syncope with abrupt loss consciousness. Given presentation, there was high suspicion etiology, further testing pursued....