Snigdha Karnakoti

ORCID: 0000-0002-9415-5323
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About
Contact & Profiles
Research Areas
  • Congenital Heart Disease Studies
  • Pulmonary Hypertension Research and Treatments
  • Cardiac Valve Diseases and Treatments
  • Cardiovascular Issues in Pregnancy
  • Cardiac Structural Anomalies and Repair
  • Aortic Disease and Treatment Approaches
  • Mycobacterium research and diagnosis
  • Cardiovascular Function and Risk Factors
  • Tuberculosis Research and Epidemiology
  • Coronary Artery Anomalies
  • Diabetes Treatment and Management
  • Hyperglycemia and glycemic control in critically ill and hospitalized patients
  • Cardiac Arrhythmias and Treatments
  • Pancreatic function and diabetes
  • Amyotrophic Lateral Sclerosis Research
  • Vascular anomalies and interventions
  • Mesenchymal stem cell research
  • Pharmacological Effects of Natural Compounds
  • Potassium and Related Disorders
  • Mechanical Circulatory Support Devices
  • Tissue Engineering and Regenerative Medicine
  • Celiac Disease Research and Management
  • Cardiovascular Disease and Adiposity
  • Botulinum Toxin and Related Neurological Disorders
  • Cardiomyopathy and Myosin Studies

Mayo Clinic
2023-2025

Mayo Clinic in Arizona
2023-2024

Cardiovascular Research Associates
2024

WinnMed
2023-2024

Mayo Clinic in Florida
2023-2024

Nanjing Medical University
2022

Bharati Vidyapeeth Deemed University
2022

Mahatma Gandhi Memorial Medical College
2022

Guntur Medical College
2022

Institute of Medical Sciences
2022

The sodium-glucose cotransporter 2 inhibitor (SGLT2i) is one of the cornerstones guideline-directed medical therapy for heart failure and has been shown to reduce risk mortality hospitalization, improve functional status quality life in patients with failure.1McMurray J.J.V. Solomon S.D. Inzucchi S.E. et al.Dapagliflozin reduced ejection fraction.N Engl J Med. 2019; 381: 1995-2008Crossref PubMed Scopus (3851) Google Scholar However, there are limited data about safety clinical benefits (or...

10.1016/j.cjcpc.2024.02.001 article EN cc-by CJC Pediatric and Congenital Heart Disease 2024-02-17

Active tuberculosis (TB) is caused by Mycobacterium (Mtb) bacteria and characterized multiple phases of infection, leading to difficulty in diagnosing treating infected individuals. Patients with latent infection (LTBI) can reactivate the active phase following perturbation dynamic bacterial immunological equilibrium, which potentially lead further Mtb transmission. However, current diagnostics often lack specificity for LTBI do not inform on TB reactivation risk. We hypothesized that immune...

10.1371/journal.pone.0316648 article EN cc-by PLoS ONE 2025-04-09

Aging is associated with acquired comorbidities that potentially influence the natural history and outcomes of adults congenital heart disease (CHD). The purpose this study was to compare clinical characteristics, as well incidence correlates all-cause mortality between different age groups. Adults CHD were categorized into 3 groups based on at baseline encounter: Group 1 (age 18–40 years); 2 41–65 years), >65 years). Of 5930 patients 37 ± 15 3009 (51%), 2422 (41%), 499 (8%) in Groups 1, 3,...

10.1016/j.ijcchd.2024.100499 article EN cc-by-nc-nd International Journal of Cardiology Congenital Heart Disease 2024-02-15

Clinical prediction of nontuberculous mycobacteria lung disease (NTM-LD) progression remains challenging. We aimed to evaluate antigen-specific immunoprofiling utilizing flow cytometry (FC) activation-induced markers (AIM) and IFN-γ enzyme-linked immune absorbent spot assay (ELISpot) accurately identifies patients with NTM-LD, differentiate those progressive from nonprogressive NTM-LD. A Prospective, single-center, laboratory technician-blinded pilot study was conducted the FC ELISpot based...

10.1371/journal.pone.0301659 article EN cc-by PLoS ONE 2024-04-19

The purpose of this study was to describe the correlates and outcomes in adults with unrepaired partial anomalous pulmonary venous return intact atrial septum (PAPVR-IAS).

10.1161/jaha.124.036403 article EN cc-by-nc-nd Journal of the American Heart Association 2024-08-27

Right ventricular (RV) systolic dysfunction and pulmonary hypertension are associated with mortality in adults coarctation of aorta (COA). The tricuspid annular plane excursion/RV pressure (TAPSE/RVSP) ratio is a validated noninvasive tool for the assessment RV-pulmonary arterial (RV-PA) coupling patients PA hypertension, but similar data lacking COA. purpose this study was to assess relationship between TAPSE/RVSP outcomes population.

10.1016/j.cjcpc.2023.05.001 article EN cc-by-nc-nd CJC Pediatric and Congenital Heart Disease 2023-05-05

Aortic valve disease is common in adults with coarctation of aorta. However, no systematic comparative analyses have been performed the clinical course aortic for male vs female patients this population. The purpose study was to compare cardiac remodelling, onset symptoms, and incidence replacement (AVR) patients.

10.1016/j.cjco.2024.08.006 article EN cc-by-nc-nd CJC Open 2024-08-23
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